Novel motif:59

name:	motif59_NCWCCARNR

Association to promoter expression in human samples<b>Summary:</b>Significance of the correlation with CAGE expression, human <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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Association to promoter expression in mouse samples <b>Summary:</b>Significance of the correlation with CAGE expression, mouse <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

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GREAT analysis results for human <b>Summary:</b>Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon<br><br>link to source dataset <br>data

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GO ID	GO Term	p-value
GO:0032526	response to retinoic acid	2.609589e-15
GO:0060351	cartilage development involved in endochondral bone morphogenesis	5.346251e-15
GO:0035814	negative regulation of renal sodium excretion	1.223747e-14
GO:0071300	cellular response to retinoic acid	1.870068e-14
GO:0034505	tooth mineralization	3.854085e-14
GO:0071299	cellular response to vitamin A	4.820250e-13
GO:0060346	bone trabecula formation	7.098297e-13
GO:0002149	hypochlorous acid biosynthetic process	7.228875e-13
GO:0044130	negative regulation of growth of symbiont in host	1.436921e-12
GO:0031670	cellular response to nutrient	2.533134e-12
GO:0002923	regulation of humoral immune response mediated by circulating immunoglobulin	4.118366e-12
GO:0048873	homeostasis of number of cells within a tissue	4.441792e-12
GO:0010718	positive regulation of epithelial to mesenchymal transition	1.002205e-11
GO:0010717	regulation of epithelial to mesenchymal transition	1.236815e-11
GO:0043903	regulation of symbiosis, encompassing mutualism through parasitism	1.337875e-11
GO:0006959	humoral immune response	1.437259e-11
GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II	1.547443e-11
GO:0006927	transformed cell apoptosis	2.485054e-11
GO:0010770	positive regulation of cell morphogenesis involved in differentiation	2.588332e-11
GO:0060124	positive regulation of growth hormone secretion	5.148628e-11
GO:0002679	respiratory burst involved in defense response	6.885544e-11
GO:0001957	intramembranous ossification	1.620324e-10
GO:0033209	tumor necrosis factor-mediated signaling pathway	2.538095e-10
GO:0044062	regulation of excretion	5.984364e-10
GO:0033189	response to vitamin A	6.277611e-10
GO:0002925	positive regulation of humoral immune response mediated by circulating immunoglobulin	6.478758e-10
GO:0060343	trabecula formation	8.190565e-10
GO:0035691	macrophage migration inhibitory factor signaling pathway	1.047739e-9
GO:0042542	response to hydrogen peroxide	1.058984e-9
GO:0071295	cellular response to vitamin	1.129172e-9
GO:0007586	digestion	1.395049e-9
GO:0061383	trabecula morphogenesis	1.556585e-9
GO:0006768	biotin metabolic process	1.780476e-9
GO:0008078	mesodermal cell migration	1.786232e-9
GO:0002876	positive regulation of chronic inflammatory response to antigenic stimulus	2.626533e-9
GO:0019884	antigen processing and presentation of exogenous antigen	3.965260e-9
GO:0019276	UDP-N-acetylgalactosamine metabolic process	4.491654e-9
GO:0051956	negative regulation of amino acid transport	4.835694e-9
GO:0007162	negative regulation of cell adhesion	6.043908e-9
GO:0042488	positive regulation of odontogenesis of dentine-containing tooth	7.013274e-9
GO:0019883	antigen processing and presentation of endogenous antigen	7.430104e-9
GO:0051488	activation of anaphase-promoting complex activity	8.623501e-9
GO:0002443	leukocyte mediated immunity	1.064061e-8
GO:0030198	extracellular matrix organization	1.347263e-8
GO:0000302	response to reactive oxygen species	1.444244e-8
GO:0030277	maintenance of gastrointestinal epithelium	1.450506e-8
GO:0002037	negative regulation of L-glutamate transport	1.495525e-8
GO:0045994	positive regulation of translational initiation by iron	1.495525e-8
GO:0002920	regulation of humoral immune response	1.556507e-8
GO:0035813	regulation of renal sodium excretion	1.564148e-8
GO:0010985	negative regulation of lipoprotein particle clearance	1.616259e-8
GO:0000389	nuclear mRNA 3'-splice site recognition	1.661723e-8
GO:0006447	regulation of translational initiation by iron	1.723149e-8
GO:0002449	lymphocyte mediated immunity	1.781039e-8
GO:2000343	positive regulation of chemokine (C-X-C motif) ligand 2 production	1.927149e-8
GO:0031536	positive regulation of exit from mitosis	1.944321e-8
GO:0046730	induction of host immune response by virus	1.944321e-8
GO:0060611	mammary gland fat development	2.049597e-8
GO:0033273	response to vitamin	2.066963e-8
GO:0010916	negative regulation of very-low-density lipoprotein particle clearance	2.320263e-8
GO:0035854	eosinophil fate commitment	2.330988e-8
GO:0030222	eosinophil differentiation	2.330988e-8
GO:0060444	branching involved in mammary gland duct morphogenesis	2.484385e-8
GO:0002478	antigen processing and presentation of exogenous peptide antigen	2.580480e-8
GO:0043901	negative regulation of multi-organism process	3.110329e-8
GO:0042790	transcription of nuclear large rRNA transcript from RNA polymerase I promoter	3.155531e-8
GO:0019724	B cell mediated immunity	3.201054e-8
GO:0002830	positive regulation of type 2 immune response	5.526638e-8
GO:0002718	regulation of cytokine production involved in immune response	5.584966e-8
GO:0016064	immunoglobulin mediated immune response	6.795909e-8
GO:0030851	granulocyte differentiation	7.026701e-8
GO:0050832	defense response to fungus	7.619502e-8
GO:0021879	forebrain neuron differentiation	7.680328e-8
GO:0042696	menarche	7.842984e-8
GO:0045630	positive regulation of T-helper 2 cell differentiation	8.176929e-8
GO:0001894	tissue homeostasis	8.429143e-8
GO:0051241	negative regulation of multicellular organismal process	8.522587e-8
GO:0043586	tongue development	9.527007e-8
GO:0048708	astrocyte differentiation	1.065080e-7
GO:0060014	granulosa cell differentiation	1.068782e-7
GO:0046732	active induction of host immune response by virus	1.512719e-7
GO:0070208	protein heterotrimerization	1.602406e-7
GO:0002712	regulation of B cell mediated immunity	1.756723e-7
GO:0009651	response to salt stress	1.817048e-7
GO:0022408	negative regulation of cell-cell adhesion	1.853715e-7
GO:0032964	collagen biosynthetic process	1.890279e-7
GO:0002460	adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	1.894937e-7
GO:0042321	negative regulation of circadian sleep/wake cycle, sleep	2.121848e-7
GO:0048872	homeostasis of number of cells	2.210755e-7
GO:0042503	tyrosine phosphorylation of Stat3 protein	2.364867e-7
GO:0045651	positive regulation of macrophage differentiation	2.391137e-7
GO:0002074	extraocular skeletal muscle development	2.913232e-7
GO:0032689	negative regulation of interferon-gamma production	3.078333e-7
GO:0002016	regulation of blood volume by renin-angiotensin	3.102576e-7
GO:0030206	chondroitin sulfate biosynthetic process	3.190404e-7
GO:0002889	regulation of immunoglobulin mediated immune response	3.282231e-7
GO:0030852	regulation of granulocyte differentiation	3.735557e-7
GO:0042506	tyrosine phosphorylation of Stat5 protein	3.833596e-7
GO:0043542	endothelial cell migration	3.864763e-7
GO:0032673	regulation of interleukin-4 production	3.969889e-7
GO:0045059	positive thymic T cell selection	4.050751e-7
GO:0003073	regulation of systemic arterial blood pressure	4.385521e-7
GO:0043206	fibril organization	4.688651e-7
GO:0061048	negative regulation of branching involved in lung morphogenesis	4.909427e-7
GO:0010900	negative regulation of phosphatidylcholine catabolic process	4.909427e-7
GO:0002678	positive regulation of chronic inflammatory response	5.023695e-7
GO:0045649	regulation of macrophage differentiation	5.031282e-7
GO:0002455	humoral immune response mediated by circulating immunoglobulin	5.162423e-7
GO:0007617	mating behavior	5.550256e-7
GO:0071356	cellular response to tumor necrosis factor	5.628010e-7
GO:0045835	negative regulation of meiosis	5.893357e-7
GO:0021892	cerebral cortex GABAergic interneuron differentiation	7.352627e-7
GO:0031297	replication fork processing	8.524718e-7
GO:0007509	mesoderm migration involved in gastrulation	8.875092e-7
GO:0001990	regulation of systemic arterial blood pressure by hormone	9.958984e-7
GO:0030826	regulation of cGMP biosynthetic process	1.008267e-6
GO:0032753	positive regulation of interleukin-4 production	1.009744e-6
GO:0006958	complement activation, classical pathway	1.037154e-6
GO:0009605	response to external stimulus	1.050420e-6
GO:0003417	growth plate cartilage development	1.134058e-6
GO:2000021	regulation of ion homeostasis	1.198773e-6
GO:0006956	complement activation	1.236583e-6
GO:0002828	regulation of type 2 immune response	1.356987e-6
GO:0003044	regulation of systemic arterial blood pressure mediated by a chemical signal	1.368759e-6
GO:0002339	B cell selection	1.545229e-6
GO:0051533	positive regulation of NFAT protein import into nucleus	1.594645e-6
GO:0048341	paraxial mesoderm formation	1.659375e-6
GO:0007589	body fluid secretion	1.690020e-6
GO:0010984	regulation of lipoprotein particle clearance	1.789818e-6
GO:0042074	cell migration involved in gastrulation	1.909590e-6
GO:0002761	regulation of myeloid leukocyte differentiation	1.974287e-6
GO:0051798	positive regulation of hair follicle development	2.119515e-6
GO:0030037	actin filament reorganization involved in cell cycle	2.170790e-6
GO:0035793	positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway	2.171818e-6
GO:0042363	fat-soluble vitamin catabolic process	2.218189e-6
GO:0060419	heart growth	2.322177e-6
GO:0002906	negative regulation of mature B cell apoptosis	2.479643e-6
GO:0050868	negative regulation of T cell activation	2.481795e-6
GO:0021872	forebrain generation of neurons	2.502332e-6
GO:0045005	maintenance of fidelity involved in DNA-dependent DNA replication	2.505939e-6
GO:0048771	tissue remodeling	2.548089e-6
GO:0051291	protein heterooligomerization	2.838356e-6
GO:0002579	positive regulation of antigen processing and presentation	2.905937e-6
GO:0070670	response to interleukin-4	3.178365e-6
GO:0010669	epithelial structure maintenance	3.186539e-6
GO:0060160	negative regulation of dopamine receptor signaling pathway	3.562995e-6
GO:0002252	immune effector process	3.567038e-6
GO:0048145	regulation of fibroblast proliferation	3.701148e-6
GO:0070345	negative regulation of fat cell proliferation	3.741989e-6
GO:0003009	skeletal muscle contraction	3.742802e-6
GO:0043029	T cell homeostasis	3.958685e-6
GO:0055017	cardiac muscle tissue growth	4.116340e-6
GO:0021542	dentate gyrus development	4.182604e-6
GO:0042744	hydrogen peroxide catabolic process	4.371286e-6
GO:0045123	cellular extravasation	4.418579e-6
GO:0002250	adaptive immune response	4.526726e-6
GO:0045581	negative regulation of T cell differentiation	4.537790e-6
GO:0002344	B cell affinity maturation	4.654120e-6
GO:0055070	copper ion homeostasis	5.012529e-6
GO:0002861	regulation of inflammatory response to antigenic stimulus	5.022457e-6
GO:0006551	leucine metabolic process	5.072583e-6
GO:0045684	positive regulation of epidermis development	5.298095e-6
GO:0006878	cellular copper ion homeostasis	5.371022e-6
GO:0032862	activation of Rho GTPase activity	5.529163e-6
GO:0045112	integrin biosynthetic process	5.753790e-6
GO:0045061	thymic T cell selection	5.783928e-6
GO:0010994	free ubiquitin chain polymerization	6.151561e-6
GO:0045580	regulation of T cell differentiation	6.223682e-6
GO:0042703	menstruation	6.229503e-6
GO:0019101	female somatic sex determination	6.229503e-6
GO:0060350	endochondral bone morphogenesis	6.537810e-6
GO:0060430	lung saccule development	6.640578e-6
GO:0008217	regulation of blood pressure	6.785898e-6
GO:0002922	positive regulation of humoral immune response	6.852085e-6
GO:0032736	positive regulation of interleukin-13 production	7.028991e-6
GO:0003416	endochondral bone growth	7.047226e-6
GO:0006884	cell volume homeostasis	7.356015e-6
GO:0060123	regulation of growth hormone secretion	7.379186e-6
GO:0007584	response to nutrient	8.051744e-6
GO:0019098	reproductive behavior	8.137688e-6
GO:0021759	globus pallidus development	9.353015e-6
GO:0002495	antigen processing and presentation of peptide antigen via MHC class II	9.448842e-6
GO:0032863	activation of Rac GTPase activity	9.448842e-6
GO:0002891	positive regulation of immunoglobulin mediated immune response	9.987423e-6
GO:0051788	response to misfolded protein	1.011996e-5
GO:0048730	epidermis morphogenesis	1.090888e-5
GO:0048298	positive regulation of isotype switching to IgA isotypes	1.145613e-5
GO:0051955	regulation of amino acid transport	1.163948e-5
GO:0035572	N-terminal peptidyl-serine dimethylation	1.243425e-5
GO:0035573	N-terminal peptidyl-serine trimethylation	1.243425e-5
GO:0018016	N-terminal peptidyl-proline dimethylation	1.243425e-5
GO:0018012	N-terminal peptidyl-alanine trimethylation	1.243425e-5
GO:0050909	sensory perception of taste	1.256389e-5
GO:0032720	negative regulation of tumor necrosis factor production	1.284800e-5
GO:0042476	odontogenesis	1.298945e-5
GO:0009817	defense response to fungus, incompatible interaction	1.310333e-5
GO:0051280	negative regulation of release of sequestered calcium ion into cytosol	1.310333e-5
GO:0030952	establishment or maintenance of cytoskeleton polarity	1.372211e-5
GO:0002700	regulation of production of molecular mediator of immune response	1.470539e-5
GO:0001878	response to yeast	1.531811e-5
GO:0090218	positive regulation of lipid kinase activity	1.534073e-5
GO:0031667	response to nutrient levels	1.540759e-5
GO:0030322	stabilization of membrane potential	1.666922e-5
GO:0071316	cellular response to nicotine	1.682374e-5
GO:0034616	response to laminar fluid shear stress	1.685676e-5
GO:0050902	leukocyte adhesive activation	1.725556e-5
GO:0051041	positive regulation of calcium-independent cell-cell adhesion	1.725556e-5
GO:0002019	regulation of renal output by angiotensin	1.725556e-5
GO:0015760	glucose-6-phosphate transport	1.728892e-5
GO:0060557	positive regulation of vitamin D biosynthetic process	1.817517e-5
GO:2000107	negative regulation of leukocyte apoptosis	1.886590e-5
GO:0045619	regulation of lymphocyte differentiation	1.896663e-5
GO:0048384	retinoic acid receptor signaling pathway	2.025206e-5
GO:0046543	development of secondary female sexual characteristics	2.133216e-5
GO:0042482	positive regulation of odontogenesis	2.157545e-5
GO:0002921	negative regulation of humoral immune response	2.157545e-5
GO:0060251	regulation of glial cell proliferation	2.348587e-5
GO:0009235	cobalamin metabolic process	2.414603e-5
GO:0085018	maintenance of symbiont-containing vacuole via substance secreted by host	2.500105e-5
GO:0035378	carbon dioxide transmembrane transport	2.500105e-5
GO:0035377	transepithelial water transport	2.500105e-5
GO:0030950	establishment or maintenance of actin cytoskeleton polarity	2.500105e-5
GO:0035265	organ growth	2.581099e-5
GO:0002026	regulation of the force of heart contraction	2.637847e-5
GO:0045060	negative thymic T cell selection	2.648785e-5
GO:0045338	farnesyl diphosphate metabolic process	2.677141e-5
GO:0001974	blood vessel remodeling	2.741943e-5
GO:0051591	response to cAMP	2.874847e-5
GO:0045109	intermediate filament organization	3.051853e-5
GO:0042487	regulation of odontogenesis of dentine-containing tooth	3.053429e-5
GO:0022010	central nervous system myelination	3.198713e-5
GO:0071529	cementum mineralization	3.281612e-5
GO:0071803	positive regulation of podosome assembly	3.436371e-5
GO:0071071	regulation of phospholipid biosynthetic process	3.485846e-5
GO:0009303	rRNA transcription	3.513883e-5
GO:0061153	trachea gland development	3.527514e-5
GO:0002903	negative regulation of B cell apoptosis	3.815632e-5
GO:0042743	hydrogen peroxide metabolic process	3.838603e-5
GO:0007635	chemosensory behavior	3.899212e-5
GO:0071732	cellular response to nitric oxide	4.008251e-5
GO:0090361	regulation of platelet-derived growth factor production	4.454115e-5
GO:0007009	plasma membrane organization	4.532080e-5
GO:0045655	regulation of monocyte differentiation	4.537075e-5
GO:0021877	forebrain neuron fate commitment	4.807267e-5
GO:0042391	regulation of membrane potential	4.918027e-5
GO:0006066	alcohol metabolic process	4.939929e-5
GO:0060349	bone morphogenesis	5.052690e-5
GO:0010719	negative regulation of epithelial to mesenchymal transition	5.105034e-5
GO:0002676	regulation of chronic inflammatory response	5.329121e-5
GO:0009225	nucleotide-sugar metabolic process	5.337330e-5
GO:0040018	positive regulation of multicellular organism growth	5.410312e-5
GO:0010388	cullin deneddylation	5.763739e-5
GO:0071072	negative regulation of phospholipid biosynthetic process	5.920106e-5
GO:0008544	epidermis development	5.925392e-5
GO:0031282	regulation of guanylate cyclase activity	6.121205e-5
GO:0002036	regulation of L-glutamate transport	6.159115e-5
GO:0044070	regulation of anion transport	6.170501e-5
GO:0035048	splicing factor protein import into nucleus	6.233200e-5
GO:0034653	retinoic acid catabolic process	6.270737e-5
GO:0045657	positive regulation of monocyte differentiation	6.287806e-5
GO:0043526	neuroprotection	6.358398e-5
GO:0017148	negative regulation of translation	6.371567e-5
GO:0046325	negative regulation of glucose import	6.534340e-5
GO:0035419	activation of MAPK activity involved in innate immune response	6.535223e-5
GO:0022600	digestive system process	6.655298e-5
GO:0060133	somatotropin secreting cell development	7.108128e-5
GO:0014002	astrocyte development	7.327179e-5
GO:0002902	regulation of B cell apoptosis	7.327179e-5
GO:0060664	epithelial cell proliferation involved in salivary gland morphogenesis	7.610561e-5
GO:0045637	regulation of myeloid cell differentiation	7.821407e-5
GO:0022601	menstrual cycle phase	7.835253e-5
GO:0051156	glucose 6-phosphate metabolic process	7.939340e-5
GO:0009416	response to light stimulus	8.011392e-5
GO:0014806	smooth muscle hyperplasia	8.201661e-5
GO:0055069	zinc ion homeostasis	8.546468e-5
GO:0002522	leukocyte migration involved in immune response	8.555470e-5
GO:0006244	pyrimidine nucleotide catabolic process	8.572848e-5
GO:0045662	negative regulation of myoblast differentiation	8.818988e-5
GO:0001976	neurological system process involved in regulation of systemic arterial blood pressure	8.847886e-5
GO:0046339	diacylglycerol metabolic process	9.333803e-5
GO:0000712	resolution of meiotic recombination intermediates	9.415356e-5
GO:0008065	establishment of blood-nerve barrier	9.523703e-5
GO:0010624	regulation of Schwann cell proliferation	9.542619e-5
GO:0045414	regulation of interleukin-8 biosynthetic process	1.002213e-4
GO:0044154	histone H3-K14 acetylation	1.019256e-4
GO:0002573	myeloid leukocyte differentiation	1.019681e-4
GO:0051148	negative regulation of muscle cell differentiation	1.025750e-4
GO:0043368	positive T cell selection	1.036631e-4
GO:0002209	behavioral defense response	1.051562e-4
GO:0042538	hyperosmotic salinity response	1.071912e-4
GO:0048469	cell maturation	1.082103e-4
GO:0051270	regulation of cellular component movement	1.109662e-4
GO:0072109	glomerular mesangium development	1.111419e-4
GO:0021984	adenohypophysis development	1.128678e-4
GO:0033081	regulation of T cell differentiation in thymus	1.131996e-4
GO:0001818	negative regulation of cytokine production	1.146134e-4
GO:0010511	regulation of phosphatidylinositol biosynthetic process	1.151716e-4
GO:0048382	mesendoderm development	1.153524e-4
GO:0048340	paraxial mesoderm morphogenesis	1.178437e-4
GO:0033327	Leydig cell differentiation	1.196730e-4
GO:0072365	regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter	1.206337e-4
GO:0009191	ribonucleoside diphosphate catabolic process	1.206337e-4
GO:0006285	base-excision repair, AP site formation	1.206337e-4
GO:0009298	GDP-mannose biosynthetic process	1.219245e-4
GO:0001826	inner cell mass cell differentiation	1.219245e-4
GO:0060396	growth hormone receptor signaling pathway	1.239627e-4
GO:0045556	positive regulation of TRAIL biosynthetic process	1.240171e-4
GO:0046032	ADP catabolic process	1.248117e-4
GO:0046709	IDP catabolic process	1.248117e-4
GO:0010771	negative regulation of cell morphogenesis involved in differentiation	1.248970e-4
GO:0060591	chondroblast differentiation	1.253973e-4
GO:0006829	zinc ion transport	1.273411e-4
GO:0043627	response to estrogen stimulus	1.274987e-4
GO:0043585	nose morphogenesis	1.292882e-4
GO:0032754	positive regulation of interleukin-5 production	1.379737e-4
GO:0045638	negative regulation of myeloid cell differentiation	1.386102e-4
GO:0022407	regulation of cell-cell adhesion	1.386106e-4
GO:0050650	chondroitin sulfate proteoglycan biosynthetic process	1.394412e-4
GO:0002863	positive regulation of inflammatory response to antigenic stimulus	1.394412e-4
GO:0060038	cardiac muscle cell proliferation	1.399283e-4
GO:0016264	gap junction assembly	1.399547e-4
GO:0001649	osteoblast differentiation	1.404590e-4
GO:0035307	positive regulation of protein dephosphorylation	1.423738e-4
GO:0060213	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening	1.466287e-4
GO:0060456	positive regulation of digestive system process	1.527283e-4
GO:0010742	macrophage derived foam cell differentiation	1.527283e-4
GO:0039020	pronephric nephron tubule development	1.540437e-4
GO:0035565	regulation of pronephros size	1.540437e-4
GO:0045948	positive regulation of translational initiation	1.541998e-4
GO:0051272	positive regulation of cellular component movement	1.558429e-4
GO:0001662	behavioral fear response	1.601519e-4
GO:0008643	carbohydrate transport	1.622137e-4
GO:0002513	tolerance induction to self antigen	1.655073e-4
GO:0045471	response to ethanol	1.671652e-4
GO:0060763	mammary duct terminal end bud growth	1.675974e-4
GO:0022614	membrane to membrane docking	1.676393e-4
GO:0051438	regulation of ubiquitin-protein ligase activity	1.687355e-4
GO:0009264	deoxyribonucleotide catabolic process	1.699075e-4
GO:0050863	regulation of T cell activation	1.701456e-4
GO:0032088	negative regulation of NF-kappaB transcription factor activity	1.705850e-4
GO:0034405	response to fluid shear stress	1.724494e-4
GO:0045136	development of secondary sexual characteristics	1.749857e-4
GO:0060751	branch elongation involved in mammary gland duct branching	1.803998e-4
GO:0052565	response to defense-related host nitric oxide production	1.824686e-4
GO:0030334	regulation of cell migration	1.831630e-4
GO:0001906	cell killing	1.832977e-4
GO:0051764	actin crosslink formation	1.838956e-4
GO:0033002	muscle cell proliferation	1.873568e-4
GO:0060693	regulation of branching involved in salivary gland morphogenesis	1.895043e-4
GO:0002504	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II	1.895043e-4
GO:0018350	protein esterification	1.901639e-4
GO:0044258	intestinal lipid catabolic process	1.901639e-4
GO:0042093	T-helper cell differentiation	1.914389e-4
GO:0010512	negative regulation of phosphatidylinositol biosynthetic process	1.936375e-4
GO:0035313	wound healing, spreading of epidermal cells	1.949584e-4
GO:0043266	regulation of potassium ion transport	1.962860e-4
GO:0042508	tyrosine phosphorylation of Stat1 protein	1.963122e-4
GO:0009620	response to fungus	1.980010e-4
GO:0045582	positive regulation of T cell differentiation	2.001557e-4
GO:0010812	negative regulation of cell-substrate adhesion	2.032509e-4
GO:0044281	small molecule metabolic process	2.052862e-4
GO:0071577	zinc ion transmembrane transport	2.074160e-4
GO:0032321	positive regulation of Rho GTPase activity	2.102518e-4
GO:0003100	regulation of systemic arterial blood pressure by endothelin	2.148764e-4
GO:0071474	cellular hyperosmotic response	2.176223e-4
GO:0033239	negative regulation of cellular amine metabolic process	2.176223e-4
GO:0032780	negative regulation of ATPase activity	2.213252e-4
GO:0009226	nucleotide-sugar biosynthetic process	2.213252e-4
GO:0060603	mammary gland duct morphogenesis	2.222504e-4
GO:0045475	locomotor rhythm	2.231862e-4
GO:0021528	commissural neuron differentiation in spinal cord	2.231862e-4
GO:0032425	positive regulation of mismatch repair	2.252735e-4
GO:0006515	misfolded or incompletely synthesized protein catabolic process	2.278215e-4
GO:0021548	pons development	2.300946e-4
GO:0043551	regulation of phosphatidylinositol 3-kinase activity	2.353226e-4
GO:0060179	male mating behavior	2.360478e-4
GO:0021754	facial nucleus development	2.390386e-4
GO:0003058	hormonal regulation of the force of heart contraction	2.390386e-4
GO:0032900	negative regulation of neurotrophin production	2.399979e-4
GO:0032244	positive regulation of nucleoside transport	2.399979e-4
GO:0043932	ossification involved in bone remodeling	2.427598e-4
GO:0007159	leukocyte cell-cell adhesion	2.508577e-4
GO:0051017	actin filament bundle assembly	2.547389e-4
GO:0044259	multicellular organismal macromolecule metabolic process	2.612746e-4
GO:0045838	positive regulation of membrane potential	2.717559e-4
GO:0048320	axial mesoderm formation	2.771342e-4
GO:0043552	positive regulation of phosphatidylinositol 3-kinase activity	2.818035e-4
GO:0022604	regulation of cell morphogenesis	2.826339e-4
GO:0003081	regulation of systemic arterial blood pressure by renin-angiotensin	2.837806e-4
GO:0050862	positive regulation of T cell receptor signaling pathway	2.841068e-4
GO:0034224	cellular response to zinc ion starvation	2.884381e-4
GO:0061088	regulation of sequestering of zinc ion	2.919255e-4
GO:0010935	regulation of macrophage cytokine production	3.046600e-4
GO:0009991	response to extracellular stimulus	3.047145e-4
GO:0043587	tongue morphogenesis	3.059850e-4
GO:0030237	female sex determination	3.153617e-4
GO:0016056	rhodopsin mediated signaling pathway	3.153617e-4
GO:0043647	inositol phosphate metabolic process	3.165663e-4
GO:0046849	bone remodeling	3.208574e-4
GO:0042501	serine phosphorylation of STAT protein	3.264889e-4
GO:0032963	collagen metabolic process	3.314746e-4
GO:0060087	relaxation of vascular smooth muscle	3.350303e-4
GO:0051016	barbed-end actin filament capping	3.353100e-4
GO:0030520	estrogen receptor signaling pathway	3.414158e-4
GO:0007512	adult heart development	3.444114e-4
GO:0032656	regulation of interleukin-13 production	3.473049e-4
GO:0002682	regulation of immune system process	3.474584e-4
GO:0021612	facial nerve structural organization	3.488735e-4
GO:0035306	positive regulation of dephosphorylation	3.503287e-4
GO:0030853	negative regulation of granulocyte differentiation	3.535148e-4
GO:0006414	translational elongation	3.574302e-4
GO:2000145	regulation of cell motility	3.594016e-4
GO:0019885	antigen processing and presentation of endogenous peptide antigen via MHC class I	3.740358e-4
GO:0010536	positive regulation of activation of Janus kinase activity	3.740358e-4
GO:0060078	regulation of postsynaptic membrane potential	3.780914e-4
GO:0032674	regulation of interleukin-5 production	3.793510e-4
GO:0051005	negative regulation of lipoprotein lipase activity	3.844336e-4
GO:0051048	negative regulation of secretion	4.037834e-4
GO:0035967	cellular response to topologically incorrect protein	4.060345e-4
GO:0006955	immune response	4.065868e-4
GO:0051023	regulation of immunoglobulin secretion	4.075660e-4
GO:0015817	histidine transport	4.110647e-4
GO:0043268	positive regulation of potassium ion transport	4.142076e-4
GO:0018293	protein-FAD linkage	4.193494e-4
GO:0006121	mitochondrial electron transport, succinate to ubiquinone	4.193494e-4
GO:0043588	skin development	4.221401e-4
GO:0002606	positive regulation of dendritic cell antigen processing and presentation	4.223620e-4
GO:2000147	positive regulation of cell motility	4.319623e-4
GO:0070228	regulation of lymphocyte apoptosis	4.359300e-4
GO:0051444	negative regulation of ubiquitin-protein ligase activity	4.363756e-4
GO:0018993	somatic sex determination	4.393564e-4
GO:0042088	T-helper 1 type immune response	4.453488e-4
GO:0014909	smooth muscle cell migration	4.477506e-4
GO:0061370	testosterone biosynthetic process	4.545160e-4
GO:0050756	fractalkine metabolic process	4.545160e-4
GO:0033595	response to genistein	4.545160e-4
GO:0072364	regulation of cellular ketone metabolic process by regulation of transcription from RNA polymerase II promoter	4.548542e-4
GO:0072262	metanephric glomerular mesangial cell proliferation involved in metanephros development	4.596977e-4
GO:0043128	positive regulation of 1-phosphatidylinositol 4-kinase activity	4.596977e-4
GO:0007595	lactation	4.758115e-4
GO:0032355	response to estradiol stimulus	4.885704e-4
GO:0071899	negative regulation of estrogen receptor binding	5.016373e-4
GO:0050710	negative regulation of cytokine secretion	5.046906e-4
GO:0045416	positive regulation of interleukin-8 biosynthetic process	5.126278e-4
GO:0001909	leukocyte mediated cytotoxicity	5.198387e-4
GO:0061049	cell growth involved in cardiac muscle cell development	5.208906e-4
GO:0014873	response to muscle activity involved in regulation of muscle adaptation	5.208906e-4
GO:0003331	positive regulation of extracellular matrix constituent secretion	5.208906e-4
GO:0001998	angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure	5.208906e-4
GO:0046148	pigment biosynthetic process	5.271778e-4
GO:0046632	alpha-beta T cell differentiation	5.337074e-4
GO:0043088	regulation of Cdc42 GTPase activity	5.371202e-4
GO:0048146	positive regulation of fibroblast proliferation	5.493104e-4
GO:0006754	ATP biosynthetic process	5.549256e-4
GO:0007096	regulation of exit from mitosis	5.632249e-4
GO:0034504	protein localization to nucleus	5.644698e-4
GO:0030335	positive regulation of cell migration	5.712868e-4
GO:0007260	tyrosine phosphorylation of STAT protein	5.715876e-4
GO:0010959	regulation of metal ion transport	5.731133e-4
GO:0033141	positive regulation of peptidyl-serine phosphorylation of STAT protein	5.768712e-4
GO:0019388	galactose catabolic process	5.768712e-4
GO:0010523	negative regulation of calcium ion transport into cytosol	5.802297e-4
GO:0045453	bone resorption	5.861685e-4
GO:0010873	positive regulation of cholesterol esterification	5.908042e-4
GO:0003099	positive regulation of the force of heart contraction by chemical signal	5.921890e-4
GO:0048386	positive regulation of retinoic acid receptor signaling pathway	6.092886e-4
GO:0060708	spongiotrophoblast differentiation	6.103237e-4
GO:0042592	homeostatic process	6.109341e-4
GO:0045065	cytotoxic T cell differentiation	6.221809e-4
GO:0021570	rhombomere 4 development	6.221809e-4
GO:0048339	paraxial mesoderm development	6.228119e-4
GO:0048147	negative regulation of fibroblast proliferation	6.354005e-4
GO:0030099	myeloid cell differentiation	6.361495e-4
GO:0006855	drug transmembrane transport	6.363467e-4
GO:0051891	positive regulation of cardioblast differentiation	6.512707e-4
GO:0060394	negative regulation of pathway-restricted SMAD protein phosphorylation	6.540438e-4
GO:0045806	negative regulation of endocytosis	6.609155e-4
GO:0060033	anatomical structure regression	6.676972e-4
GO:0046415	urate metabolic process	6.676972e-4
GO:0009181	purine ribonucleoside diphosphate catabolic process	6.799806e-4
GO:0043400	cortisol secretion	6.802939e-4
GO:0031669	cellular response to nutrient levels	6.804426e-4
GO:0051461	positive regulation of corticotropin secretion	7.028378e-4
GO:0002924	negative regulation of humoral immune response mediated by circulating immunoglobulin	7.028378e-4
GO:0032696	negative regulation of interleukin-13 production	7.216329e-4
GO:0032803	regulation of low-density lipoprotein particle receptor catabolic process	7.370189e-4
GO:0072181	mesonephric duct formation	7.386028e-4
GO:0071733	transcriptional activation by promoter-enhancer looping	7.386028e-4
GO:0002438	acute inflammatory response to antigenic stimulus	7.386028e-4
GO:0010724	regulation of definitive erythrocyte differentiation	7.386028e-4
GO:0051873	killing by host of symbiont cells	7.410828e-4
GO:0032796	uropod organization	7.410828e-4
GO:0018963	phthalate metabolic process	7.410828e-4
GO:0050878	regulation of body fluid levels	7.534844e-4
GO:0007263	nitric oxide mediated signal transduction	7.591426e-4
GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway	7.678188e-4
GO:0060135	maternal process involved in female pregnancy	7.681458e-4
GO:0048871	multicellular organismal homeostasis	7.721096e-4
GO:0072376	protein activation cascade	7.769375e-4
GO:0006552	leucine catabolic process	7.774865e-4

GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon <br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0045940	positive regulation of steroid metabolic process	2.735468e-15
GO:0001957	intramembranous ossification	5.113595e-13
GO:0016064	immunoglobulin mediated immune response	1.448146e-12
GO:0070245	positive regulation of thymocyte apoptosis	2.375476e-12
GO:0019724	B cell mediated immunity	5.100873e-12
GO:0002449	lymphocyte mediated immunity	9.572203e-12
GO:0070234	positive regulation of T cell apoptosis	1.513278e-11
GO:0010873	positive regulation of cholesterol esterification	7.419960e-11
GO:0019218	regulation of steroid metabolic process	2.633143e-10
GO:0010872	regulation of cholesterol esterification	2.753603e-10
GO:0045834	positive regulation of lipid metabolic process	2.762419e-10
GO:0070208	protein heterotrimerization	3.083388e-10
GO:0033700	phospholipid efflux	4.016514e-10
GO:0044236	multicellular organismal metabolic process	4.224710e-10
GO:0002579	positive regulation of antigen processing and presentation	4.543222e-10
GO:0071417	cellular response to organic nitrogen	8.389771e-10
GO:0002443	leukocyte mediated immunity	8.433901e-10
GO:0070243	regulation of thymocyte apoptosis	8.836210e-10
GO:0016126	sterol biosynthetic process	2.186411e-9
GO:0060346	bone trabecula formation	3.261929e-9
GO:0071418	cellular response to amine stimulus	4.391875e-9
GO:0090023	positive regulation of neutrophil chemotaxis	5.283163e-9
GO:0070228	regulation of lymphocyte apoptosis	7.775800e-9
GO:0070232	regulation of T cell apoptosis	9.882451e-9
GO:0070230	positive regulation of lymphocyte apoptosis	1.437051e-8
GO:0031017	exocrine pancreas development	1.571925e-8
GO:0010916	negative regulation of very-low-density lipoprotein particle clearance	1.587090e-8
GO:0001516	prostaglandin biosynthetic process	2.134309e-8
GO:0007620	copulation	2.332556e-8
GO:0002460	adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	2.393451e-8
GO:0035691	macrophage migration inhibitory factor signaling pathway	3.524559e-8
GO:0009303	rRNA transcription	3.659404e-8
GO:0033085	negative regulation of T cell differentiation in thymus	4.777145e-8
GO:0006693	prostaglandin metabolic process	4.781020e-8
GO:0034505	tooth mineralization	5.046276e-8
GO:2000106	regulation of leukocyte apoptosis	5.590990e-8
GO:0019216	regulation of lipid metabolic process	5.932786e-8
GO:0071230	cellular response to amino acid stimulus	6.485899e-8
GO:0070508	cholesterol import	6.705885e-8
GO:0044259	multicellular organismal macromolecule metabolic process	7.050354e-8
GO:0010985	negative regulation of lipoprotein particle clearance	7.263502e-8
GO:0030818	negative regulation of cAMP biosynthetic process	7.681002e-8
GO:0032963	collagen metabolic process	8.089569e-8
GO:0014044	Schwann cell development	8.124312e-8
GO:0046890	regulation of lipid biosynthetic process	9.048341e-8
GO:0002577	regulation of antigen processing and presentation	9.479566e-8
GO:0046889	positive regulation of lipid biosynthetic process	1.332051e-7
GO:0046885	regulation of hormone biosynthetic process	1.419196e-7
GO:0015844	monoamine transport	1.678724e-7
GO:0050921	positive regulation of chemotaxis	1.742900e-7
GO:0006633	fatty acid biosynthetic process	1.790716e-7
GO:0071229	cellular response to acid	1.963043e-7
GO:0030595	leukocyte chemotaxis	1.963043e-7
GO:0034382	chylomicron remnant clearance	2.009503e-7
GO:0051004	regulation of lipoprotein lipase activity	2.480914e-7
GO:0045980	negative regulation of nucleotide metabolic process	2.692854e-7
GO:0046886	positive regulation of hormone biosynthetic process	2.697773e-7
GO:0002455	humoral immune response mediated by circulating immunoglobulin	2.850556e-7
GO:0019884	antigen processing and presentation of exogenous antigen	3.562043e-7
GO:0002478	antigen processing and presentation of exogenous peptide antigen	3.821588e-7
GO:0050900	leukocyte migration	4.391693e-7
GO:0033344	cholesterol efflux	4.581963e-7
GO:0070328	triglyceride homeostasis	5.126350e-7
GO:0050994	regulation of lipid catabolic process	5.646826e-7
GO:0010893	positive regulation of steroid biosynthetic process	5.825244e-7
GO:0031960	response to corticosteroid stimulus	6.301919e-7
GO:0002606	positive regulation of dendritic cell antigen processing and presentation	6.714869e-7
GO:0010984	regulation of lipoprotein particle clearance	6.956739e-7
GO:0002250	adaptive immune response	6.972823e-7
GO:0070206	protein trimerization	7.533988e-7
GO:0002886	regulation of myeloid leukocyte mediated immunity	8.231640e-7
GO:0048545	response to steroid hormone stimulus	8.508437e-7
GO:0016125	sterol metabolic process	8.703901e-7
GO:0010901	regulation of very-low-density lipoprotein particle remodeling	8.961309e-7
GO:0048771	tissue remodeling	9.023254e-7
GO:0006695	cholesterol biosynthetic process	9.180410e-7
GO:0051347	positive regulation of transferase activity	1.000027e-6
GO:0032103	positive regulation of response to external stimulus	1.068310e-6
GO:0071874	cellular response to norepinephrine stimulus	1.103195e-6
GO:0046456	icosanoid biosynthetic process	1.266283e-6
GO:0006952	defense response	1.328883e-6
GO:0042790	transcription of nuclear large rRNA transcript from RNA polymerase I promoter	1.453385e-6
GO:0043691	reverse cholesterol transport	1.613646e-6
GO:0090030	regulation of steroid hormone biosynthetic process	1.704508e-6
GO:0090022	regulation of neutrophil chemotaxis	1.922597e-6
GO:0010243	response to organic nitrogen	1.998503e-6
GO:0050920	regulation of chemotaxis	2.099867e-6
GO:0048148	behavioral response to cocaine	2.107030e-6
GO:0050713	negative regulation of interleukin-1 beta secretion	2.184115e-6
GO:0014037	Schwann cell differentiation	2.453513e-6
GO:0002821	positive regulation of adaptive immune response	2.483308e-6
GO:0060191	regulation of lipase activity	2.515973e-6
GO:0006636	unsaturated fatty acid biosynthetic process	2.616951e-6
GO:0038028	insulin receptor signaling pathway via phosphatidylinositol 3-kinase cascade	2.651070e-6
GO:0006690	icosanoid metabolic process	2.994291e-6
GO:0090031	positive regulation of steroid hormone biosynthetic process	3.126590e-6
GO:0030865	cortical cytoskeleton organization	3.148268e-6
GO:0060213	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening	3.209052e-6
GO:0032352	positive regulation of hormone metabolic process	3.218372e-6
GO:0042304	regulation of fatty acid biosynthetic process	3.237273e-6
GO:0042415	norepinephrine metabolic process	3.268179e-6
GO:0046628	positive regulation of insulin receptor signaling pathway	3.380565e-6
GO:0000305	response to oxygen radical	3.486448e-6
GO:0019430	removal of superoxide radicals	3.504280e-6
GO:0014075	response to amine stimulus	3.548248e-6
GO:0002718	regulation of cytokine production involved in immune response	3.854152e-6
GO:0032964	collagen biosynthetic process	3.915407e-6
GO:0033081	regulation of T cell differentiation in thymus	4.002115e-6
GO:0033275	actin-myosin filament sliding	4.052700e-6
GO:0022011	myelination in peripheral nervous system	4.090380e-6
GO:0050995	negative regulation of lipid catabolic process	4.099619e-6
GO:2000108	positive regulation of leukocyte apoptosis	4.561853e-6
GO:0042149	cellular response to glucose starvation	4.652086e-6
GO:0006707	cholesterol catabolic process	5.072981e-6
GO:0033674	positive regulation of kinase activity	5.140178e-6
GO:0050810	regulation of steroid biosynthetic process	5.217455e-6
GO:0021782	glial cell development	5.218525e-6
GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II	5.339205e-6
GO:0050872	white fat cell differentiation	6.018154e-6
GO:0002642	positive regulation of immunoglobulin biosynthetic process	6.294479e-6
GO:0006694	steroid biosynthetic process	6.665031e-6
GO:0000303	response to superoxide	7.308633e-6
GO:0033505	floor plate morphogenesis	8.183418e-6
GO:0043031	negative regulation of macrophage activation	8.204654e-6
GO:0044243	multicellular organismal catabolic process	8.288519e-6
GO:0032488	Cdc42 protein signal transduction	8.540489e-6
GO:0045860	positive regulation of protein kinase activity	8.779099e-6
GO:0061001	regulation of dendritic spine morphogenesis	8.937152e-6
GO:0032094	response to food	9.094424e-6
GO:0051005	negative regulation of lipoprotein lipase activity	1.025497e-5
GO:0043085	positive regulation of catalytic activity	1.054121e-5
GO:0006833	water transport	1.128313e-5
GO:0060343	trabecula formation	1.146278e-5
GO:0061077	chaperone-mediated protein folding	1.215009e-5
GO:0072376	protein activation cascade	1.268147e-5
GO:0015850	organic alcohol transport	1.268401e-5
GO:0051937	catecholamine transport	1.331316e-5
GO:0045907	positive regulation of vasoconstriction	1.334981e-5
GO:0007493	endodermal cell fate determination	1.369890e-5
GO:0010765	positive regulation of sodium ion transport	1.373907e-5
GO:0070252	actin-mediated cell contraction	1.417481e-5
GO:0050865	regulation of cell activation	1.435923e-5
GO:0044341	sodium-dependent phosphate transport	1.441550e-5
GO:0090342	regulation of cell aging	1.488649e-5
GO:0043300	regulation of leukocyte degranulation	1.622600e-5
GO:0007320	insemination	1.686732e-5
GO:0001974	blood vessel remodeling	1.744403e-5
GO:0002251	organ or tissue specific immune response	1.746465e-5
GO:0010903	negative regulation of very-low-density lipoprotein particle remodeling	1.802397e-5
GO:0007614	short-term memory	1.860368e-5
GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	1.864325e-5
GO:0009628	response to abiotic stimulus	1.878455e-5
GO:0008203	cholesterol metabolic process	1.975306e-5
GO:0045581	negative regulation of T cell differentiation	2.027664e-5
GO:0007522	visceral muscle development	2.078473e-5
GO:0032369	negative regulation of lipid transport	2.161221e-5
GO:0002385	mucosal immune response	2.172459e-5
GO:0002252	immune effector process	2.318026e-5
GO:0070741	response to interleukin-6	2.381848e-5
GO:0002690	positive regulation of leukocyte chemotaxis	2.467289e-5
GO:0008211	glucocorticoid metabolic process	2.523283e-5
GO:0045760	positive regulation of action potential	2.689188e-5
GO:0035307	positive regulation of protein dephosphorylation	2.701961e-5
GO:0032374	regulation of cholesterol transport	2.783580e-5
GO:0002694	regulation of leukocyte activation	2.821033e-5
GO:0050432	catecholamine secretion	3.005844e-5
GO:0031424	keratinization	3.053358e-5
GO:0042487	regulation of odontogenesis of dentine-containing tooth	3.115074e-5
GO:0044240	multicellular organismal lipid catabolic process	3.244991e-5
GO:0002344	B cell affinity maturation	3.333487e-5
GO:0001985	negative regulation of heart rate involved in baroreceptor response to increased systemic arterial blood pressure	3.411262e-5
GO:0046394	carboxylic acid biosynthetic process	3.490613e-5
GO:0006956	complement activation	3.684219e-5
GO:0035306	positive regulation of dephosphorylation	3.811832e-5
GO:0030049	muscle filament sliding	4.029900e-5
GO:0050706	regulation of interleukin-1 beta secretion	4.079308e-5
GO:0090343	positive regulation of cell aging	4.177189e-5
GO:0045725	positive regulation of glycogen biosynthetic process	4.294859e-5
GO:0008340	determination of adult lifespan	4.437961e-5
GO:0060192	negative regulation of lipase activity	4.461806e-5
GO:0045087	innate immune response	4.587758e-5
GO:0009719	response to endogenous stimulus	4.868140e-5
GO:0030199	collagen fibril organization	4.897780e-5
GO:0051085	chaperone mediated protein folding requiring cofactor	4.974295e-5
GO:0002906	negative regulation of mature B cell apoptosis	5.304953e-5
GO:0016925	protein sumoylation	5.586551e-5
GO:0048242	epinephrine secretion	5.593238e-5
GO:0007422	peripheral nervous system development	5.600355e-5
GO:0032350	regulation of hormone metabolic process	5.814618e-5
GO:0043200	response to amino acid stimulus	5.817345e-5
GO:0032375	negative regulation of cholesterol transport	6.051230e-5
GO:0002864	regulation of acute inflammatory response to antigenic stimulus	6.051230e-5
GO:0046847	filopodium assembly	6.212925e-5
GO:0015724	formate transport	6.313509e-5
GO:0002442	serotonin secretion involved in inflammatory response	6.320079e-5
GO:0006378	mRNA polyadenylation	6.431067e-5
GO:0002673	regulation of acute inflammatory response	6.504378e-5
GO:0048739	cardiac muscle fiber development	6.538569e-5
GO:0010741	negative regulation of intracellular protein kinase cascade	6.565759e-5
GO:0043535	regulation of blood vessel endothelial cell migration	6.633373e-5
GO:0002740	negative regulation of cytokine secretion involved in immune response	6.839721e-5
GO:0035249	synaptic transmission, glutamatergic	6.928053e-5
GO:0006954	inflammatory response	6.983733e-5
GO:0050711	negative regulation of interleukin-1 secretion	7.231952e-5
GO:0042104	positive regulation of activated T cell proliferation	7.595210e-5
GO:0019217	regulation of fatty acid metabolic process	7.660814e-5
GO:0001935	endothelial cell proliferation	8.338305e-5
GO:0010906	regulation of glucose metabolic process	8.358078e-5
GO:0010565	regulation of cellular ketone metabolic process	8.364762e-5
GO:0002688	regulation of leukocyte chemotaxis	8.384015e-5
GO:0006958	complement activation, classical pathway	8.427515e-5
GO:0033003	regulation of mast cell activation	8.520214e-5
GO:2000772	regulation of cellular senescence	8.560522e-5
GO:0002604	regulation of dendritic cell antigen processing and presentation	9.045849e-5
GO:0030035	microspike assembly	9.196900e-5
GO:0050790	regulation of catalytic activity	9.366737e-5
GO:0045937	positive regulation of phosphate metabolic process	9.499492e-5
GO:0008610	lipid biosynthetic process	9.874702e-5
GO:0051338	regulation of transferase activity	1.024037e-4
GO:0070875	positive regulation of glycogen metabolic process	1.029566e-4
GO:0043503	skeletal muscle fiber adaptation	1.037412e-4
GO:0001826	inner cell mass cell differentiation	1.037412e-4
GO:0007512	adult heart development	1.076770e-4
GO:0048644	muscle organ morphogenesis	1.095079e-4
GO:0010900	negative regulation of phosphatidylcholine catabolic process	1.102891e-4
GO:0055009	atrial cardiac muscle tissue morphogenesis	1.105142e-4
GO:0044093	positive regulation of molecular function	1.108031e-4
GO:0031440	regulation of mRNA 3'-end processing	1.108119e-4
GO:0045922	negative regulation of fatty acid metabolic process	1.157646e-4
GO:0017157	regulation of exocytosis	1.184118e-4
GO:0043549	regulation of kinase activity	1.196899e-4
GO:0071495	cellular response to endogenous stimulus	1.222780e-4
GO:0042044	fluid transport	1.250668e-4
GO:0014738	regulation of muscle hyperplasia	1.259470e-4
GO:0005979	regulation of glycogen biosynthetic process	1.266474e-4
GO:0045859	regulation of protein kinase activity	1.275695e-4
GO:0002697	regulation of immune effector process	1.311077e-4
GO:0045620	negative regulation of lymphocyte differentiation	1.328718e-4
GO:0007418	ventral midline development	1.377456e-4
GO:0002115	store-operated calcium entry	1.394758e-4
GO:0050730	regulation of peptidyl-tyrosine phosphorylation	1.402627e-4
GO:0060696	regulation of phospholipid catabolic process	1.402946e-4
GO:0001817	regulation of cytokine production	1.461381e-4
GO:0002883	regulation of hypersensitivity	1.491547e-4
GO:0018149	peptide cross-linking	1.495998e-4
GO:0006547	histidine metabolic process	1.544757e-4
GO:0030301	cholesterol transport	1.557485e-4
GO:0002827	positive regulation of T-helper 1 type immune response	1.579389e-4
GO:0043067	regulation of programmed cell death	1.588470e-4
GO:0002554	serotonin secretion by platelet	1.635255e-4
GO:2000467	positive regulation of glycogen (starch) synthase activity	1.657584e-4
GO:0050863	regulation of T cell activation	1.671871e-4
GO:0002381	immunoglobulin production involved in immunoglobulin mediated immune response	1.693944e-4
GO:0034369	plasma lipoprotein particle remodeling	1.704348e-4
GO:0051345	positive regulation of hydrolase activity	1.761282e-4
GO:0044255	cellular lipid metabolic process	1.763709e-4
GO:2000343	positive regulation of chemokine (C-X-C motif) ligand 2 production	1.767126e-4
GO:0050778	positive regulation of immune response	1.786524e-4
GO:0050704	regulation of interleukin-1 secretion	1.807757e-4
GO:0043467	regulation of generation of precursor metabolites and energy	1.825744e-4
GO:0006066	alcohol metabolic process	1.828730e-4
GO:0060299	negative regulation of sarcomere organization	1.848997e-4
GO:0060307	regulation of ventricular cardiomyocyte membrane repolarization	1.848997e-4
GO:0042703	menstruation	1.848997e-4
GO:0019101	female somatic sex determination	1.848997e-4
GO:0031442	positive regulation of mRNA 3'-end processing	1.896075e-4
GO:0006669	sphinganine-1-phosphate biosynthetic process	1.943694e-4
GO:0002687	positive regulation of leukocyte migration	1.973257e-4
GO:0043462	regulation of ATPase activity	1.990002e-4
GO:0006826	iron ion transport	2.003028e-4
GO:0072365	regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter	2.038550e-4
GO:0009991	response to extracellular stimulus	2.050978e-4
GO:0051384	response to glucocorticoid stimulus	2.087131e-4
GO:0002739	regulation of cytokine secretion involved in immune response	2.095091e-4
GO:0002504	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II	2.221750e-4
GO:0070873	regulation of glycogen metabolic process	2.252104e-4
GO:0055088	lipid homeostasis	2.264130e-4
GO:0033136	serine phosphorylation of STAT3 protein	2.274065e-4
GO:0021508	floor plate formation	2.274065e-4
GO:0042981	regulation of apoptosis	2.286831e-4
GO:0061383	trabecula morphogenesis	2.315539e-4
GO:0015914	phospholipid transport	2.382047e-4
GO:0071827	plasma lipoprotein particle organization	2.449742e-4
GO:0048935	peripheral nervous system neuron development	2.486578e-4
GO:0002495	antigen processing and presentation of peptide antigen via MHC class II	2.492810e-4
GO:0033504	floor plate development	2.562703e-4
GO:0050776	regulation of immune response	2.631873e-4
GO:0002440	production of molecular mediator of immune response	2.667571e-4
GO:0006706	steroid catabolic process	2.710909e-4
GO:0002576	platelet degranulation	2.713769e-4
GO:0010987	negative regulation of high-density lipoprotein particle clearance	2.750965e-4
GO:0010897	negative regulation of triglyceride catabolic process	2.750965e-4
GO:0015684	ferrous iron transport	2.804267e-4
GO:0010288	response to lead ion	2.825321e-4
GO:0002903	negative regulation of B cell apoptosis	2.825321e-4
GO:0006548	histidine catabolic process	2.899779e-4
GO:0032516	positive regulation of phosphoprotein phosphatase activity	2.901070e-4
GO:0002027	regulation of heart rate	2.919927e-4
GO:0002885	positive regulation of hypersensitivity	2.929098e-4
GO:0045723	positive regulation of fatty acid biosynthetic process	2.944116e-4
GO:0051084	'de novo' posttranslational protein folding	2.945583e-4
GO:0006629	lipid metabolic process	3.087388e-4
GO:0010896	regulation of triglyceride catabolic process	3.091037e-4
GO:0070887	cellular response to chemical stimulus	3.093130e-4
GO:0071732	cellular response to nitric oxide	3.136907e-4
GO:0009725	response to hormone stimulus	3.226463e-4
GO:0046006	regulation of activated T cell proliferation	3.231779e-4
GO:0060627	regulation of vesicle-mediated transport	3.232210e-4
GO:0006941	striated muscle contraction	3.232580e-4
GO:0001932	regulation of protein phosphorylation	3.331919e-4
GO:0043518	negative regulation of DNA damage response, signal transduction by p53 class mediator	3.339811e-4
GO:0019220	regulation of phosphate metabolic process	3.428358e-4
GO:0042632	cholesterol homeostasis	3.496457e-4
GO:0002700	regulation of production of molecular mediator of immune response	3.540998e-4
GO:0051291	protein heterooligomerization	3.595334e-4
GO:0015837	amine transport	3.632302e-4
GO:0050651	dermatan sulfate proteoglycan biosynthetic process	3.686873e-4
GO:0009103	lipopolysaccharide biosynthetic process	3.720282e-4
GO:0048241	epinephrine transport	3.955505e-4
GO:0033131	regulation of glucokinase activity	3.975684e-4
GO:0051591	response to cAMP	4.019198e-4
GO:0031016	pancreas development	4.127616e-4
GO:0030300	regulation of intestinal cholesterol absorption	4.185555e-4
GO:0010907	positive regulation of glucose metabolic process	4.198303e-4
GO:0045740	positive regulation of DNA replication	4.226363e-4
GO:0071731	response to nitric oxide	4.311375e-4
GO:0042137	sequestering of neurotransmitter	4.373335e-4
GO:0042661	regulation of mesodermal cell fate specification	4.411715e-4
GO:0001101	response to acid	4.437437e-4
GO:0090201	negative regulation of release of cytochrome c from mitochondria	4.462252e-4
GO:0042325	regulation of phosphorylation	4.776740e-4
GO:0030240	skeletal muscle thin filament assembly	4.824856e-4
GO:0030866	cortical actin cytoskeleton organization	4.891904e-4
GO:0000105	histidine biosynthetic process	5.053492e-4
GO:0010936	negative regulation of macrophage cytokine production	5.132775e-4
GO:0002026	regulation of the force of heart contraction	5.271399e-4
GO:0032733	positive regulation of interleukin-10 production	5.295234e-4
GO:0016310	phosphorylation	5.589741e-4
GO:0046069	cGMP catabolic process	5.594763e-4
GO:0065009	regulation of molecular function	5.662329e-4
GO:0002866	positive regulation of acute inflammatory response to antigenic stimulus	5.681561e-4
GO:0050795	regulation of behavior	5.940435e-4
GO:0006109	regulation of carbohydrate metabolic process	6.058080e-4
GO:0032287	peripheral nervous system myelin maintenance	6.149451e-4
GO:0031399	regulation of protein modification process	6.172115e-4
GO:0009134	nucleoside diphosphate catabolic process	6.212721e-4
GO:0008366	axon ensheathment	6.216517e-4
GO:0002377	immunoglobulin production	6.406455e-4
GO:0032912	negative regulation of transforming growth factor beta2 production	6.698679e-4
GO:0034435	cholesterol esterification	6.965038e-4
GO:0040017	positive regulation of locomotion	7.280910e-4
GO:0034380	high-density lipoprotein particle assembly	7.345886e-4
GO:0050685	positive regulation of mRNA processing	7.573664e-4
GO:0070665	positive regulation of leukocyte proliferation	7.620792e-4
GO:0016338	calcium-independent cell-cell adhesion	7.766561e-4
GO:0032878	regulation of establishment or maintenance of cell polarity	7.809442e-4
GO:0002407	dendritic cell chemotaxis	7.876490e-4
GO:0022010	central nervous system myelination	7.881147e-4
GO:0071702	organic substance transport	7.886421e-4
GO:0021936	regulation of cerebellar granule cell precursor proliferation	7.994723e-4
GO:0007009	plasma membrane organization	8.006938e-4
GO:0055072	iron ion homeostasis	8.141989e-4
GO:0097035	regulation of membrane lipid distribution	8.157757e-4
GO:0014049	positive regulation of glutamate secretion	8.256757e-4
GO:0010675	regulation of cellular carbohydrate metabolic process	8.382831e-4
GO:0043084	penile erection	8.492896e-4
GO:0042501	serine phosphorylation of STAT protein	8.492896e-4
GO:0010812	negative regulation of cell-substrate adhesion	8.505219e-4
GO:0051272	positive regulation of cellular component movement	8.678040e-4
GO:0015749	monosaccharide transport	8.925689e-4
GO:0021819	layer formation in cerebral cortex	8.947420e-4
GO:2000107	negative regulation of leukocyte apoptosis	9.010299e-4
GO:0042327	positive regulation of phosphorylation	9.013107e-4
GO:0050871	positive regulation of B cell activation	9.034465e-4
GO:0071622	regulation of granulocyte chemotaxis	9.068707e-4
GO:0010614	negative regulation of cardiac muscle hypertrophy	9.077003e-4
GO:0006760	folic acid-containing compound metabolic process	9.102553e-4
GO:0070305	response to cGMP	9.114654e-4
GO:0035264	multicellular organism growth	9.344540e-4
GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway	9.589911e-4
GO:0060326	cell chemotaxis	9.648011e-4
GO:0042552	myelination	9.666680e-4
GO:0001934	positive regulation of protein phosphorylation	9.694045e-4
GO:0051182	coenzyme transport	9.727091e-4
GO:2000178	negative regulation of neural precursor cell proliferation	9.828588e-4
GO:0006796	phosphate-containing compound metabolic process	9.828768e-4
GO:0006360	transcription from RNA polymerase I promoter	9.859234e-4
GO:0032368	regulation of lipid transport	9.973567e-4
GO:0043304	regulation of mast cell degranulation	9.978218e-4
GO:0032946	positive regulation of mononuclear cell proliferation	1.007072e-3
GO:0060415	muscle tissue morphogenesis	1.007168e-3
GO:0015791	polyol transport	1.009494e-3
GO:0001819	positive regulation of cytokine production	1.012737e-3
GO:0000492	box C/D snoRNP assembly	1.013972e-3
GO:0032530	regulation of microvillus organization	1.031028e-3
GO:0002074	extraocular skeletal muscle development	1.031028e-3
GO:0006487	protein N-linked glycosylation	1.054467e-3
GO:0043405	regulation of MAP kinase activity	1.064580e-3
GO:0002830	positive regulation of type 2 immune response	1.076614e-3
GO:0001820	serotonin secretion	1.076614e-3
GO:0031427	response to methotrexate	1.083767e-3
GO:0043217	myelin maintenance	1.104417e-3
GO:0002685	regulation of leukocyte migration	1.104498e-3
GO:0030239	myofibril assembly	1.110463e-3
GO:0002824	positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	1.116001e-3
GO:0060620	regulation of cholesterol import	1.122081e-3
GO:0045717	negative regulation of fatty acid biosynthetic process	1.124243e-3
GO:0030593	neutrophil chemotaxis	1.126779e-3
GO:0072539	T-helper 17 cell differentiation	1.153882e-3
GO:0006545	glycine biosynthetic process	1.153882e-3
GO:0015876	acetyl-CoA transport	1.159017e-3
GO:0031579	membrane raft organization	1.161948e-3
GO:0010823	negative regulation of mitochondrion organization	1.161948e-3
GO:0043525	positive regulation of neuron apoptosis	1.164030e-3
GO:0071705	nitrogen compound transport	1.167967e-3
GO:0071593	lymphocyte aggregation	1.168725e-3
GO:0006668	sphinganine-1-phosphate metabolic process	1.168725e-3
GO:0010989	negative regulation of low-density lipoprotein particle clearance	1.189130e-3
GO:0060426	lung vasculature development	1.190505e-3
GO:0051249	regulation of lymphocyte activation	1.199899e-3
GO:0007586	digestion	1.200089e-3
GO:2001021	negative regulation of response to DNA damage stimulus	1.225558e-3
GO:0030826	regulation of cGMP biosynthetic process	1.235910e-3
GO:0035304	regulation of protein dephosphorylation	1.237832e-3
GO:0051270	regulation of cellular component movement	1.239858e-3
GO:0042711	maternal behavior	1.246430e-3
GO:0045103	intermediate filament-based process	1.285278e-3
GO:0050710	negative regulation of cytokine secretion	1.285641e-3
GO:0002861	regulation of inflammatory response to antigenic stimulus	1.288881e-3
GO:0015920	lipopolysaccharide transport	1.302113e-3
GO:0010982	regulation of high-density lipoprotein particle clearance	1.302113e-3
GO:0045840	positive regulation of mitosis	1.314085e-3
GO:0007517	muscle organ development	1.332689e-3
GO:0006631	fatty acid metabolic process	1.348242e-3
GO:0044283	small molecule biosynthetic process	1.350269e-3
GO:0055010	ventricular cardiac muscle tissue morphogenesis	1.361781e-3
GO:0031032	actomyosin structure organization	1.375535e-3
GO:0060621	negative regulation of cholesterol import	1.383543e-3
GO:0060052	neurofilament cytoskeleton organization	1.389008e-3
GO:0031295	T cell costimulation	1.389699e-3
GO:0010259	multicellular organismal aging	1.405418e-3
GO:0071299	cellular response to vitamin A	1.424070e-3
GO:0009416	response to light stimulus	1.434073e-3
GO:0002684	positive regulation of immune system process	1.463680e-3
GO:0006959	humoral immune response	1.499442e-3
GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I	1.500245e-3
GO:0042136	neurotransmitter biosynthetic process	1.500245e-3
GO:0002426	immunoglobulin production in mucosal tissue	1.500245e-3
GO:0006879	cellular iron ion homeostasis	1.509726e-3
GO:0002376	immune system process	1.512771e-3
GO:0009100	glycoprotein metabolic process	1.533004e-3
GO:0071385	cellular response to glucocorticoid stimulus	1.535067e-3
GO:0007618	mating	1.545733e-3
GO:0043270	positive regulation of ion transport	1.562210e-3
GO:0048261	negative regulation of receptor-mediated endocytosis	1.570720e-3
GO:0046604	positive regulation of mitotic centrosome separation	1.585789e-3
GO:0043252	sodium-independent organic anion transport	1.585789e-3
GO:0002561	basophil degranulation	1.585789e-3
GO:0032532	regulation of microvillus length	1.585789e-3
GO:0031124	mRNA 3'-end processing	1.596613e-3
GO:0003229	ventricular cardiac muscle tissue development	1.631145e-3
GO:0007602	phototransduction	1.646771e-3
GO:2000189	positive regulation of cholesterol homeostasis	1.669470e-3
GO:0050861	positive regulation of B cell receptor signaling pathway	1.669470e-3
GO:0048320	axial mesoderm formation	1.669470e-3
GO:0050671	positive regulation of lymphocyte proliferation	1.671250e-3
GO:0032515	negative regulation of phosphoprotein phosphatase activity	1.674968e-3
GO:0046655	folic acid metabolic process	1.679527e-3
GO:0008016	regulation of heart contraction	1.699944e-3
GO:0051336	regulation of hydrolase activity	1.717496e-3
GO:0035094	response to nicotine	1.719516e-3
GO:0048520	positive regulation of behavior	1.728041e-3
GO:0001993	regulation of systemic arterial blood pressure by norepinephrine-epinephrine	1.734682e-3
GO:0010935	regulation of macrophage cytokine production	1.734682e-3
GO:0045924	regulation of female receptivity	1.746501e-3
GO:0060351	cartilage development involved in endochondral bone morphogenesis	1.794052e-3
GO:0003044	regulation of systemic arterial blood pressure mediated by a chemical signal	1.794052e-3
GO:0043589	skin morphogenesis	1.810700e-3
GO:0006641	triglyceride metabolic process	1.812845e-3
GO:0008645	hexose transport	1.814278e-3
GO:2000147	positive regulation of cell motility	1.824085e-3
GO:2000273	positive regulation of receptor activity	1.843714e-3
GO:0010976	positive regulation of neuron projection development	1.866851e-3
GO:0010941	regulation of cell death	1.871033e-3
GO:2000465	regulation of glycogen (starch) synthase activity	1.902771e-3
GO:0071383	cellular response to steroid hormone stimulus	1.919016e-3
GO:0071453	cellular response to oxygen levels	1.943281e-3
GO:2000412	positive regulation of thymocyte migration	1.947963e-3
GO:0031998	regulation of fatty acid beta-oxidation	1.954401e-3
GO:0014051	gamma-aminobutyric acid secretion	1.960486e-3
GO:0010460	positive regulation of heart rate	1.983240e-3
GO:0006013	mannose metabolic process	1.999132e-3
GO:0071300	cellular response to retinoic acid	2.030868e-3
GO:0002125	maternal aggressive behavior	2.032280e-3
GO:0060709	glycogen cell development involved in embryonic placenta development	2.032280e-3
GO:0072011	glomerular endothelium development	2.032280e-3
GO:0018993	somatic sex determination	2.032280e-3
GO:0031214	biomineral tissue development	2.050324e-3
GO:0043502	regulation of muscle adaptation	2.054010e-3
GO:0006555	methionine metabolic process	2.077714e-3