Novel motif:55

name:	motif55_CGTTATAGCC

Association to promoter expression in human samples<b>Summary:</b>Significance of the correlation with CAGE expression, human <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

---

Association to promoter expression in mouse samples <b>Summary:</b>Significance of the correlation with CAGE expression, mouse <br><b>Analyst:</b> Michiel de Hoon<br><br>link to source dataset <br>data

---

GREAT analysis results for human <b>Summary:</b>Genomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon<br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0044140	negative regulation of growth of symbiont on or near host surface	5.201796e-10
GO:0043316	cytotoxic T cell degranulation	8.446866e-10
GO:0016202	regulation of striated muscle tissue development	1.396210e-9
GO:0090129	positive regulation of synapse maturation	2.652190e-9
GO:0090128	regulation of synapse maturation	6.297832e-9
GO:0048634	regulation of muscle organ development	7.030134e-9
GO:0014912	negative regulation of smooth muscle cell migration	1.780607e-8
GO:0015820	leucine transport	3.143717e-8
GO:0051883	killing of cells in other organism involved in symbiotic interaction	4.693843e-8
GO:0035886	vascular smooth muscle cell differentiation	4.941103e-8
GO:0003310	pancreatic A cell differentiation	5.770018e-8
GO:0045663	positive regulation of myoblast differentiation	7.803909e-8
GO:0015827	tryptophan transport	8.709426e-8
GO:0031053	primary miRNA processing	9.731054e-8
GO:0050927	positive regulation of positive chemotaxis	9.795331e-8
GO:0051873	killing by host of symbiont cells	1.050824e-7
GO:0070493	thrombin receptor signaling pathway	1.061514e-7
GO:0018192	enzyme active site formation via L-cysteine persulfide	1.075059e-7
GO:0050926	regulation of positive chemotaxis	2.718712e-7
GO:0015801	aromatic amino acid transport	6.607240e-7
GO:0010226	response to lithium ion	7.037490e-7
GO:0071285	cellular response to lithium ion	1.266530e-6
GO:0033561	regulation of water loss via skin	1.397744e-6
GO:0035048	splicing factor protein import into nucleus	2.087558e-6
GO:0032909	regulation of transforming growth factor beta2 production	2.604056e-6
GO:0021678	third ventricle development	3.412400e-6
GO:0070368	positive regulation of hepatocyte differentiation	4.104182e-6
GO:0007183	SMAD protein complex assembly	4.812689e-6
GO:0015870	acetylcholine transport	4.952796e-6
GO:0009414	response to water deprivation	5.178714e-6
GO:0050775	positive regulation of dendrite morphogenesis	5.247046e-6
GO:0042363	fat-soluble vitamin catabolic process	5.900499e-6
GO:0008291	acetylcholine metabolic process	6.074876e-6
GO:0060155	platelet dense granule organization	7.053484e-6
GO:0043503	skeletal muscle fiber adaptation	7.646332e-6
GO:0001756	somitogenesis	1.164612e-5
GO:0060662	salivary gland cavitation	1.292257e-5
GO:0060356	leucine import	1.327632e-5
GO:0032790	ribosome disassembly	1.327632e-5
GO:0061053	somite development	1.345665e-5
GO:0048660	regulation of smooth muscle cell proliferation	1.881421e-5
GO:0031627	telomeric loop formation	1.951599e-5
GO:0043320	natural killer cell degranulation	1.982941e-5
GO:0021592	fourth ventricle development	1.982941e-5
GO:0015804	neutral amino acid transport	2.110679e-5
GO:0002051	osteoblast fate commitment	2.128250e-5
GO:0001933	negative regulation of protein phosphorylation	2.266469e-5
GO:0003308	negative regulation of Wnt receptor signaling pathway involved in heart development	2.277379e-5
GO:0090082	positive regulation of heart induction by negative regulation of canonical Wnt receptor signaling pathway	2.311239e-5
GO:0060947	cardiac vascular smooth muscle cell differentiation	2.493611e-5
GO:0048075	positive regulation of eye pigmentation	2.622813e-5
GO:0006313	transposition, DNA-mediated	2.622813e-5
GO:0035196	production of miRNAs involved in gene silencing by miRNA	2.637595e-5
GO:0048565	digestive tract development	3.050940e-5
GO:0003002	regionalization	3.095102e-5
GO:0032988	ribonucleoprotein complex disassembly	3.107703e-5
GO:0031640	killing of cells of other organism	3.292579e-5
GO:0060043	regulation of cardiac muscle cell proliferation	3.382977e-5
GO:0003099	positive regulation of the force of heart contraction by chemical signal	3.410681e-5
GO:0032910	regulation of transforming growth factor beta3 production	3.588186e-5
GO:0055024	regulation of cardiac muscle tissue development	3.952174e-5
GO:0003329	pancreatic PP cell fate commitment	4.160535e-5
GO:0003326	pancreatic A cell fate commitment	4.160535e-5
GO:0050702	interleukin-1 beta secretion	4.306227e-5
GO:0010922	positive regulation of phosphatase activity	4.591908e-5
GO:0006930	substrate-dependent cell migration, cell extension	4.593244e-5
GO:0042088	T-helper 1 type immune response	4.755637e-5
GO:0070918	production of small RNA involved in gene silencing by RNA	4.784357e-5
GO:0042310	vasoconstriction	4.826839e-5
GO:0003058	hormonal regulation of the force of heart contraction	4.927867e-5
GO:0031848	protection from non-homologous end joining at telomere	5.410601e-5
GO:0060045	positive regulation of cardiac muscle cell proliferation	5.703170e-5
GO:0071918	urea transmembrane transport	5.967481e-5
GO:0048662	negative regulation of smooth muscle cell proliferation	6.509824e-5
GO:0006884	cell volume homeostasis	6.519687e-5
GO:0003307	regulation of Wnt receptor signaling pathway involved in heart development	6.597401e-5
GO:0014910	regulation of smooth muscle cell migration	6.783189e-5
GO:0055021	regulation of cardiac muscle tissue growth	7.368459e-5
GO:0000422	mitochondrion degradation	7.741088e-5
GO:0048642	negative regulation of skeletal muscle tissue development	7.833600e-5
GO:0032976	release of matrix enzymes from mitochondria	8.936423e-5
GO:0048597	post-embryonic camera-type eye morphogenesis	8.936423e-5
GO:0046674	induction of retinal programmed cell death	8.936423e-5
GO:0001777	T cell homeostatic proliferation	8.936423e-5
GO:0002352	B cell negative selection	8.936423e-5
GO:0009234	menaquinone biosynthetic process	8.936423e-5
GO:0043654	recognition of apoptotic cell	9.009340e-5
GO:0014829	vascular smooth muscle contraction	9.133287e-5
GO:0070366	regulation of hepatocyte differentiation	9.212531e-5
GO:0008292	acetylcholine biosynthetic process	9.212531e-5
GO:0048073	regulation of eye pigmentation	9.212531e-5
GO:0031558	induction of apoptosis in response to chemical stimulus	9.376679e-5
GO:0006383	transcription from RNA polymerase III promoter	1.000768e-4
GO:0090081	regulation of heart induction by regulation of canonical Wnt receptor signaling pathway	1.017025e-4
GO:0019348	dolichol metabolic process	1.020753e-4
GO:0048641	regulation of skeletal muscle tissue development	1.116086e-4
GO:0035269	protein O-linked mannosylation	1.144344e-4
GO:0032611	interleukin-1 beta production	1.235313e-4
GO:0045425	positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process	1.287022e-4
GO:0001867	complement activation, lectin pathway	1.331732e-4
GO:0009952	anterior/posterior pattern specification	1.383545e-4
GO:0031557	induction of programmed cell death in response to chemical stimulus	1.385475e-4
GO:0045661	regulation of myoblast differentiation	1.403284e-4
GO:0002030	inhibitory G-protein coupled receptor phosphorylation	1.408234e-4
GO:0045423	regulation of granulocyte macrophage colony-stimulating factor biosynthetic process	1.442994e-4
GO:0042127	regulation of cell proliferation	1.453592e-4
GO:0090263	positive regulation of canonical Wnt receptor signaling pathway	1.695064e-4
GO:0007231	osmosensory signaling pathway	1.761777e-4
GO:0060319	primitive erythrocyte differentiation	1.761777e-4
GO:0002575	basophil chemotaxis	1.761777e-4
GO:0001906	cell killing	1.770127e-4
GO:0046689	response to mercury ion	1.778306e-4
GO:0030240	skeletal muscle thin filament assembly	1.896434e-4
GO:0046641	positive regulation of alpha-beta T cell proliferation	1.983467e-4
GO:0032214	negative regulation of telomere maintenance via semi-conservative replication	1.991373e-4
GO:0070079	histone H4-R3 demethylation	1.991373e-4
GO:0070078	histone H3-R2 demethylation	1.991373e-4
GO:0060633	negative regulation of transcription initiation from RNA polymerase II promoter	1.991373e-4
GO:0001309	age-dependent telomere shortening	1.991373e-4
GO:0003360	brainstem development	1.991373e-4
GO:0018395	peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine	1.991373e-4
GO:0046655	folic acid metabolic process	2.012392e-4
GO:0046670	positive regulation of retinal cell programmed cell death	2.186661e-4
GO:0050930	induction of positive chemotaxis	2.335333e-4
GO:0019049	evasion of host defenses by virus	2.364826e-4
GO:0007340	acrosome reaction	2.531495e-4
GO:0060420	regulation of heart growth	2.544604e-4
GO:0000173	inactivation of MAPK activity involved in osmosensory signaling pathway	2.596333e-4
GO:0046640	regulation of alpha-beta T cell proliferation	2.634270e-4
GO:0000088	mitotic prophase	2.668468e-4
GO:0006998	nuclear envelope organization	2.826435e-4
GO:0042593	glucose homeostasis	3.039197e-4
GO:0055123	digestive system development	3.083518e-4
GO:0071635	negative regulation of transforming growth factor beta production	3.175802e-4
GO:0060059	embryonic retina morphogenesis in camera-type eye	3.218834e-4
GO:0021612	facial nerve structural organization	3.222394e-4
GO:0006922	cleavage of lamin	3.226217e-4
GO:0051488	activation of anaphase-promoting complex activity	3.354073e-4
GO:0033363	secretory granule organization	3.466128e-4
GO:0014733	regulation of skeletal muscle adaptation	3.531738e-4
GO:0006422	aspartyl-tRNA aminoacylation	3.531738e-4
GO:0001983	baroreceptor response to increased systemic arterial blood pressure	3.596259e-4
GO:0097084	vascular smooth muscle cell development	3.608371e-4
GO:0034645	cellular macromolecule biosynthetic process	3.654527e-4
GO:0045086	positive regulation of interleukin-2 biosynthetic process	3.663892e-4
GO:0046690	response to tellurium ion	3.767716e-4
GO:0009645	response to low light intensity stimulus	3.767716e-4
GO:0030177	positive regulation of Wnt receptor signaling pathway	3.826174e-4
GO:0001975	response to amphetamine	3.911325e-4
GO:0009059	macromolecule biosynthetic process	3.915017e-4
GO:0043501	skeletal muscle adaptation	4.017988e-4
GO:0042369	vitamin D catabolic process	4.026193e-4
GO:0018126	protein hydroxylation	4.107044e-4
GO:2000178	negative regulation of neural precursor cell proliferation	4.130762e-4
GO:0001994	norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure	4.188606e-4
GO:0060623	regulation of chromosome condensation	4.280582e-4
GO:0051987	positive regulation of attachment of spindle microtubules to kinetochore	4.280582e-4
GO:0071283	cellular response to iron(III) ion	4.280582e-4
GO:0050983	deoxyhypusine biosynthetic process from spermidine, using deoxyhypusine synthase	4.280582e-4
GO:0021512	spinal cord anterior/posterior patterning	4.280582e-4
GO:0046680	response to DDT	4.280582e-4
GO:0061030	epithelial cell differentiation involved in mammary gland alveolus development	4.280992e-4
GO:0016233	telomere capping	4.469255e-4
GO:0006412	translation	4.770768e-4
GO:0032916	positive regulation of transforming growth factor beta3 production	4.860573e-4
GO:0071340	skeletal muscle nicotinic acetylcholine receptor clustering	5.156222e-4
GO:0006669	sphinganine-1-phosphate biosynthetic process	5.156222e-4
GO:0031943	regulation of glucocorticoid metabolic process	5.304886e-4
GO:0015824	proline transport	5.463988e-4
GO:0016926	protein desumoylation	5.546500e-4
GO:0035282	segmentation	5.763931e-4
GO:0045687	positive regulation of glial cell differentiation	6.027135e-4
GO:0015842	synaptic vesicle amine transport	6.064249e-4
GO:0003057	regulation of the force of heart contraction by chemical signal	6.204936e-4
GO:0048814	regulation of dendrite morphogenesis	6.257658e-4
GO:0032912	negative regulation of transforming growth factor beta2 production	6.581029e-4
GO:0007338	single fertilization	6.711162e-4
GO:0007389	pattern specification process	6.844653e-4
GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity	6.879038e-4
GO:0014866	skeletal myofibril assembly	7.052137e-4
GO:0000281	cytokinesis after mitosis	7.240977e-4
GO:0060580	ventral spinal cord interneuron fate determination	7.333315e-4
GO:0003327	type B pancreatic cell fate commitment	7.333315e-4
GO:0042984	regulation of amyloid precursor protein biosynthetic process	7.378264e-4
GO:0090224	regulation of spindle organization	7.616836e-4
GO:0031400	negative regulation of protein modification process	7.692998e-4
GO:0035194	posttranscriptional gene silencing by RNA	7.754481e-4
GO:0009566	fertilization	7.903962e-4
GO:0044403	symbiosis, encompassing mutualism through parasitism	8.103774e-4
GO:0003018	vascular process in circulatory system	8.136623e-4
GO:0048268	clathrin coat assembly	8.516607e-4
GO:0072592	oxygen metabolic process	8.718748e-4
GO:0048711	positive regulation of astrocyte differentiation	8.912332e-4
GO:0030327	prenylated protein catabolic process	8.958807e-4
GO:0060290	transdifferentiation	8.990240e-4
GO:0000712	resolution of meiotic recombination intermediates	9.102146e-4
GO:0031946	regulation of glucocorticoid biosynthetic process	9.382822e-4
GO:0048505	regulation of timing of cell differentiation	9.649427e-4
GO:0071681	cellular response to indole-3-methanol	9.668114e-4
GO:0032328	alanine transport	9.720569e-4
GO:0051149	positive regulation of muscle cell differentiation	9.943215e-4
GO:0090304	nucleic acid metabolic process	1.024637e-3
GO:0019242	methylglyoxal biosynthetic process	1.045283e-3
GO:0051823	regulation of synapse structural plasticity	1.057640e-3
GO:0007498	mesoderm development	1.084851e-3
GO:0038027	apolipoprotein A-I-mediated signaling pathway	1.090188e-3
GO:0048665	neuron fate specification	1.098348e-3
GO:0032984	macromolecular complex disassembly	1.110985e-3
GO:0001840	neural plate development	1.118943e-3
GO:0031444	slow-twitch skeletal muscle fiber contraction	1.125709e-3
GO:0034621	cellular macromolecular complex subunit organization	1.133491e-3
GO:0045936	negative regulation of phosphate metabolic process	1.141343e-3
GO:0006499	N-terminal protein myristoylation	1.145280e-3
GO:0071169	establishment of protein localization to chromatin	1.148378e-3
GO:0006430	lysyl-tRNA aminoacylation	1.148378e-3
GO:0046947	hydroxylysine biosynthetic process	1.148378e-3
GO:0006948	induction by virus of host cell-cell fusion	1.148378e-3
GO:0045234	protein palmitoleylation	1.148378e-3
GO:0021569	rhombomere 3 development	1.192281e-3
GO:0016576	histone dephosphorylation	1.237120e-3
GO:0071875	adrenergic receptor signaling pathway	1.273990e-3
GO:0050701	interleukin-1 secretion	1.273990e-3
GO:0051702	interaction with symbiont	1.274949e-3
GO:0071634	regulation of transforming growth factor beta production	1.350324e-3
GO:0031577	spindle checkpoint	1.352163e-3
GO:0035195	gene silencing by miRNA	1.386626e-3
GO:0030433	ER-associated protein catabolic process	1.394856e-3
GO:0003161	cardiac conduction system development	1.405431e-3
GO:0034120	positive regulation of erythrocyte aggregation	1.439536e-3
GO:0016556	mRNA modification	1.440383e-3
GO:0006498	N-terminal protein lipidation	1.446094e-3
GO:0009438	methylglyoxal metabolic process	1.446094e-3
GO:0003148	outflow tract septum morphogenesis	1.475279e-3
GO:2000177	regulation of neural precursor cell proliferation	1.509762e-3
GO:0001561	fatty acid alpha-oxidation	1.551622e-3
GO:0031018	endocrine pancreas development	1.560319e-3
GO:0048663	neuron fate commitment	1.575532e-3
GO:0071985	multivesicular body sorting pathway	1.602704e-3
GO:0021570	rhombomere 4 development	1.640158e-3
GO:0031047	gene silencing by RNA	1.650322e-3
GO:0060749	mammary gland alveolus development	1.668198e-3
GO:0006924	activation-induced cell death of T cells	1.684016e-3
GO:0010834	telomere maintenance via telomere shortening	1.684201e-3
GO:0002042	cell migration involved in sprouting angiogenesis	1.702996e-3
GO:0031077	post-embryonic camera-type eye development	1.754761e-3
GO:0007339	binding of sperm to zona pellucida	1.754761e-3
GO:0060644	mammary gland epithelial cell differentiation	1.763353e-3
GO:0001547	antral ovarian follicle growth	1.778164e-3
GO:0034470	ncRNA processing	1.792108e-3
GO:0030048	actin filament-based movement	1.792108e-3
GO:0046015	regulation of transcription by glucose	1.794755e-3
GO:2000008	regulation of protein localization at cell surface	1.822614e-3
GO:0006325	chromatin organization	1.845372e-3
GO:0003321	positive regulation of blood pressure by epinephrine-norepinephrine	1.869391e-3
GO:0042110	T cell activation	1.900047e-3
GO:0002541	activation of plasma proteins involved in acute inflammatory response	1.949834e-3
GO:0010921	regulation of phosphatase activity	2.006630e-3
GO:0045823	positive regulation of heart contraction	2.014308e-3
GO:0051657	maintenance of organelle location	2.025148e-3
GO:0009263	deoxyribonucleotide biosynthetic process	2.025148e-3
GO:0001839	neural plate morphogenesis	2.028421e-3
GO:0042116	macrophage activation	2.055326e-3
GO:0002286	T cell activation involved in immune response	2.055326e-3
GO:0042985	negative regulation of amyloid precursor protein biosynthetic process	2.060713e-3
GO:0048520	positive regulation of behavior	2.076099e-3
GO:0048747	muscle fiber development	2.152040e-3
GO:0071174	mitotic cell cycle spindle checkpoint	2.219309e-3
GO:0032288	myelin assembly	2.236707e-3
GO:0050921	positive regulation of chemotaxis	2.239609e-3
GO:0051496	positive regulation of stress fiber assembly	2.248104e-3
GO:0045627	positive regulation of T-helper 1 cell differentiation	2.267977e-3
GO:0042326	negative regulation of phosphorylation	2.278291e-3
GO:0009912	auditory receptor cell fate commitment	2.311343e-3
GO:0032612	interleukin-1 production	2.347053e-3
GO:0060345	spleen trabecula formation	2.358077e-3
GO:0043933	macromolecular complex subunit organization	2.363863e-3
GO:0032911	negative regulation of transforming growth factor beta1 production	2.436741e-3
GO:0010739	positive regulation of protein kinase A signaling cascade	2.440885e-3
GO:0006497	protein lipidation	2.443580e-3
GO:0001993	regulation of systemic arterial blood pressure by norepinephrine-epinephrine	2.453721e-3
GO:0048617	embryonic foregut morphogenesis	2.507555e-3
GO:0016568	chromatin modification	2.511531e-3
GO:0034660	ncRNA metabolic process	2.514774e-3
GO:0071248	cellular response to metal ion	2.533799e-3
GO:0009062	fatty acid catabolic process	2.544435e-3
GO:0090169	regulation of spindle assembly	2.557903e-3
GO:0090234	regulation of kinetochore assembly	2.557903e-3
GO:2000143	negative regulation of transcription initiation, DNA-dependent	2.570952e-3
GO:0030901	midbrain development	2.665296e-3
GO:0031297	replication fork processing	2.675942e-3
GO:0051281	positive regulation of release of sequestered calcium ion into cytosol	2.702178e-3
GO:0021555	midbrain-hindbrain boundary morphogenesis	2.711364e-3
GO:0006901	vesicle coating	2.769596e-3
GO:0045076	regulation of interleukin-2 biosynthetic process	2.789011e-3
GO:0002011	morphogenesis of an epithelial sheet	2.818965e-3
GO:0070306	lens fiber cell differentiation	2.825024e-3
GO:0009953	dorsal/ventral pattern formation	2.825404e-3
GO:0009880	embryonic pattern specification	2.827951e-3
GO:0046184	aldehyde biosynthetic process	2.837820e-3
GO:0048713	regulation of oligodendrocyte differentiation	2.849120e-3
GO:0021610	facial nerve morphogenesis	2.897256e-3
GO:0043179	rhythmic excitation	2.898707e-3
GO:0043114	regulation of vascular permeability	2.922139e-3
GO:0042246	tissue regeneration	2.968326e-3
GO:0021978	telencephalon regionalization	2.979362e-3
GO:0006398	histone mRNA 3'-end processing	3.140023e-3
GO:0045843	negative regulation of striated muscle tissue development	3.143095e-3
GO:0008216	spermidine metabolic process	3.144012e-3
GO:0030949	positive regulation of vascular endothelial growth factor receptor signaling pathway	3.174167e-3
GO:0042158	lipoprotein biosynthetic process	3.177953e-3
GO:0050821	protein stabilization	3.182592e-3
GO:0071241	cellular response to inorganic substance	3.257424e-3
GO:0090381	regulation of heart induction	3.275387e-3
GO:0017183	peptidyl-diphthamide biosynthetic process from peptidyl-histidine	3.324099e-3
GO:0090037	positive regulation of protein kinase C signaling cascade	3.325070e-3
GO:0010561	negative regulation of glycoprotein biosynthetic process	3.347972e-3
GO:0014015	positive regulation of gliogenesis	3.419413e-3
GO:0032774	RNA biosynthetic process	3.420025e-3
GO:0034623	cellular macromolecular complex disassembly	3.480456e-3
GO:0061031	endodermal digestive tract morphogenesis	3.504422e-3
GO:0019058	viral infectious cycle	3.513998e-3
GO:0009415	response to water	3.564465e-3
GO:0043206	fibril organization	3.611196e-3
GO:0035412	regulation of catenin import into nucleus	3.668262e-3
GO:0001978	regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback	3.669064e-3
GO:0042886	amide transport	3.669064e-3
GO:0021993	initiation of neural tube closure	3.721148e-3
GO:0015808	L-alanine transport	3.728576e-3
GO:0006413	translational initiation	3.826429e-3
GO:0046620	regulation of organ growth	3.851057e-3
GO:0071470	cellular response to osmotic stress	3.875792e-3
GO:0008286	insulin receptor signaling pathway	3.904161e-3
GO:0035036	sperm-egg recognition	3.915306e-3
GO:0021511	spinal cord patterning	3.954972e-3
GO:0018202	peptidyl-histidine modification	3.963802e-3
GO:0031016	pancreas development	4.037556e-3
GO:0045989	positive regulation of striated muscle contraction	4.037576e-3
GO:0048742	regulation of skeletal muscle fiber development	4.092377e-3
GO:0008156	negative regulation of DNA replication	4.110534e-3
GO:0021561	facial nerve development	4.123764e-3
GO:0051984	positive regulation of chromosome segregation	4.143193e-3
GO:0030264	nuclear fragmentation involved in apoptotic nuclear change	4.143193e-3
GO:0008635	activation of caspase activity by cytochrome c	4.210465e-3
GO:0051153	regulation of striated muscle cell differentiation	4.222847e-3
GO:0022007	convergent extension involved in neural plate elongation	4.223972e-3
GO:0001986	negative regulation of the force of heart contraction involved in baroreceptor response to increased systemic arterial blood pressure	4.223972e-3
GO:0030101	natural killer cell activation	4.282831e-3
GO:0001775	cell activation	4.300523e-3
GO:0022415	viral reproductive process	4.342022e-3
GO:0070286	axonemal dynein complex assembly	4.366035e-3
GO:0046013	regulation of T cell homeostatic proliferation	4.366035e-3
GO:0048050	post-embryonic eye morphogenesis	4.366035e-3
GO:0015884	folic acid transport	4.468935e-3
GO:0045321	leukocyte activation	4.479726e-3
GO:0061351	neural precursor cell proliferation	4.493598e-3
GO:0032488	Cdc42 protein signal transduction	4.560021e-3
GO:0043402	glucocorticoid mediated signaling pathway	4.560021e-3
GO:0043367	CD4-positive, alpha-beta T cell differentiation	4.612908e-3
GO:0048741	skeletal muscle fiber development	4.637325e-3
GO:0010467	gene expression	4.646229e-3
GO:0043378	positive regulation of CD8-positive, alpha-beta T cell differentiation	4.648342e-3
GO:0035509	negative regulation of myosin-light-chain-phosphatase activity	4.648342e-3
GO:0030819	positive regulation of cAMP biosynthetic process	4.684686e-3
GO:0002268	follicular dendritic cell differentiation	4.691920e-3
GO:0035372	protein localization to microtubule	4.733498e-3
GO:0021935	cerebellar granule cell precursor tangential migration	4.733498e-3
GO:0007224	smoothened signaling pathway	4.736521e-3
GO:0045005	maintenance of fidelity involved in DNA-dependent DNA replication	4.936806e-3
GO:0060215	primitive hemopoiesis	5.031070e-3
GO:0015840	urea transport	5.057554e-3
GO:0030816	positive regulation of cAMP metabolic process	5.058490e-3
GO:0046649	lymphocyte activation	5.203628e-3
GO:0031468	nuclear envelope reassembly	5.273120e-3
GO:0030042	actin filament depolymerization	5.273120e-3
GO:0070885	negative regulation of calcineurin-NFAT signaling pathway	5.285158e-3
GO:0007089	traversing start control point of mitotic cell cycle	5.444172e-3
GO:0060466	activation of meiosis involved in egg activation	5.481304e-3
GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	5.510147e-3
GO:0043534	blood vessel endothelial cell migration	5.521978e-3
GO:0045648	positive regulation of erythrocyte differentiation	5.636598e-3
GO:0061072	iris morphogenesis	5.688910e-3
GO:0060585	positive regulation of prostaglandin-endoperoxide synthase activity	5.715751e-3
GO:0030071	regulation of mitotic metaphase/anaphase transition	5.767096e-3
GO:0032516	positive regulation of phosphoprotein phosphatase activity	5.852323e-3
GO:0072329	monocarboxylic acid catabolic process	5.866208e-3
GO:0034633	retinol transport	5.872845e-3
GO:0071242	cellular response to ammonium ion	5.872845e-3
GO:0006409	tRNA export from nucleus	5.872845e-3
GO:0043331	response to dsRNA	5.969069e-3
GO:0008228	opsonization	6.046919e-3
GO:0007195	inhibition of adenylate cyclase activity by dopamine receptor signaling pathway	6.083579e-3
GO:0050764	regulation of phagocytosis	6.097055e-3
GO:0030049	muscle filament sliding	6.166677e-3
GO:0050769	positive regulation of neurogenesis	6.200658e-3
GO:0032007	negative regulation of TOR signaling cascade	6.238441e-3
GO:0007507	heart development	6.274656e-3
GO:0055001	muscle cell development	6.440652e-3
GO:0043241	protein complex disassembly	6.513667e-3
GO:0010107	potassium ion import	6.521990e-3
GO:0034227	tRNA thio-modification	6.521990e-3
GO:0002098	tRNA wobble uridine modification	6.521990e-3
GO:0021772	olfactory bulb development	6.537692e-3
GO:0061302	smooth muscle cell-matrix adhesion	6.570619e-3
GO:0043117	positive regulation of vascular permeability	6.644347e-3
GO:0071156	regulation of cell cycle arrest	6.711548e-3
GO:0010041	response to iron(III) ion	6.741329e-3
GO:0051685	maintenance of ER location	6.741329e-3
GO:0019083	viral transcription	6.878208e-3
GO:0001542	ovulation from ovarian follicle	6.899314e-3
GO:0003309	type B pancreatic cell differentiation	6.910998e-3
GO:0045091	regulation of retroviral genome replication	6.926336e-3
GO:0051647	nucleus localization	6.931900e-3
GO:0007420	brain development	6.961881e-3
GO:0031958	corticosteroid receptor signaling pathway	7.129141e-3
GO:0006900	membrane budding	7.129506e-3
GO:0021846	cell proliferation in forebrain	7.318145e-3
GO:0002274	myeloid leukocyte activation	7.413561e-3
GO:0042558	pteridine-containing compound metabolic process	7.520359e-3
GO:0042664	negative regulation of endodermal cell fate specification	7.601459e-3
GO:0060921	sinoatrial node cell differentiation	7.601459e-3
GO:0060975	cardioblast migration to the midline involved in heart field formation	7.601459e-3
GO:0035481	positive regulation of Notch signaling pathway involved in heart induction	7.601459e-3
GO:0003259	cardioblast anterior-lateral migration	7.601459e-3
GO:0003236	sinus venosus morphogenesis	7.601459e-3
GO:0003241	growth involved in heart morphogenesis	7.601459e-3
GO:0003210	cardiac atrium formation	7.601459e-3
GO:0007440	foregut morphogenesis	7.763336e-3
GO:0048715	negative regulation of oligodendrocyte differentiation	7.872118e-3
GO:0043001	Golgi to plasma membrane protein transport	7.913454e-3
GO:0002543	activation of blood coagulation via clotting cascade	7.948415e-3
GO:0048096	chromatin-mediated maintenance of transcription	8.039132e-3
GO:0070682	proteasome regulatory particle assembly	8.041441e-3
GO:0043148	mitotic spindle stabilization	8.041441e-3
GO:0034725	DNA replication-dependent nucleosome disassembly	8.041441e-3
GO:0071887	leukocyte apoptosis	8.149682e-3
GO:0048566	embryonic digestive tract development	8.184854e-3
GO:0035710	CD4-positive, alpha-beta T cell activation	8.226926e-3
GO:0021530	spinal cord oligodendrocyte cell fate specification	8.242828e-3
GO:0034653	retinoic acid catabolic process	8.245150e-3
GO:0008053	mitochondrial fusion	8.245150e-3
GO:0070252	actin-mediated cell contraction	8.323147e-3
GO:0071173	spindle assembly checkpoint	8.370911e-3
GO:0048710	regulation of astrocyte differentiation	8.573643e-3
GO:0035413	positive regulation of catenin import into nucleus	8.625695e-3
GO:0050920	regulation of chemotaxis	8.645755e-3
GO:0007186	G-protein coupled receptor protein signaling pathway	8.714174e-3
GO:0051276	chromosome organization	8.730481e-3
GO:0009642	response to light intensity	8.736947e-3
GO:0033344	cholesterol efflux	8.770477e-3
GO:0048469	cell maturation	8.780417e-3
GO:0060458	right lung development	8.798972e-3
GO:0060024	rhythmic synaptic transmission	8.798972e-3
GO:0030149	sphingolipid catabolic process	8.963792e-3
GO:0055015	ventricular cardiac muscle cell development	9.034737e-3
GO:0014826	vein smooth muscle contraction	9.094631e-3
GO:0042993	positive regulation of transcription factor import into nucleus	9.227381e-3
GO:0034380	high-density lipoprotein particle assembly	9.244801e-3
GO:0006268	DNA unwinding involved in replication	9.379578e-3
GO:0021537	telencephalon development	9.388012e-3
GO:0032868	response to insulin stimulus	9.512899e-3
GO:0070227	lymphocyte apoptosis	9.516879e-3
GO:0021903	rostrocaudal neural tube patterning	9.559170e-3
GO:0051856	adhesion to symbiont	9.586256e-3
GO:0003221	right ventricular cardiac muscle tissue morphogenesis	9.586256e-3
GO:0035871	protein K11-linked deubiquitination	9.690416e-3
GO:0015866	ADP transport	9.690416e-3
GO:0031915	positive regulation of synaptic plasticity	9.690759e-3
GO:0051439	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	9.691522e-3
GO:0009249	protein lipoylation	9.706929e-3
GO:0006108	malate metabolic process	9.706929e-3
GO:0001544	initiation of primordial ovarian follicle growth	9.843428e-3
GO:0071359	cellular response to dsRNA	1.009077e-2
GO:0045841	negative regulation of mitotic metaphase/anaphase transition	1.010723e-2
GO:0061003	positive regulation of dendritic spine morphogenesis	1.031333e-2
GO:0008612	peptidyl-lysine modification to hypusine	1.031333e-2
GO:0006706	steroid catabolic process	1.032893e-2
GO:0006139	nucleobase-containing compound metabolic process	1.048111e-2
GO:0045933	positive regulation of muscle contraction	1.048959e-2
GO:0016458	gene silencing	1.080872e-2
GO:0046836	glycolipid transport	1.082114e-2
GO:0060039	pericardium development	1.082416e-2
GO:0048664	neuron fate determination	1.087364e-2
GO:0007020	microtubule nucleation	1.087364e-2
GO:0008633	activation of pro-apoptotic gene products	1.090655e-2
GO:0006359	regulation of transcription from RNA polymerase III promoter	1.109108e-2
GO:0045625	regulation of T-helper 1 cell differentiation	1.109797e-2
GO:0002779	antibacterial peptide secretion	1.118816e-2
GO:0032269	negative regulation of cellular protein metabolic process	1.127065e-2
GO:0001556	oocyte maturation	1.129630e-2
GO:0048661	positive regulation of smooth muscle cell proliferation	1.130544e-2
GO:0010694	positive regulation of alkaline phosphatase activity	1.133958e-2
GO:0042631	cellular response to water deprivation	1.152152e-2
GO:0032980	keratinocyte activation	1.152152e-2
GO:0006775	fat-soluble vitamin metabolic process	1.159893e-2
GO:0032233	positive regulation of actin filament bundle assembly	1.178094e-2
GO:0010667	negative regulation of cardiac muscle cell apoptosis	1.179880e-2
GO:0022411	cellular component disassembly	1.183278e-2
GO:0045686	negative regulation of glial cell differentiation	1.185514e-2
GO:0060402	calcium ion transport into cytosol	1.185848e-2
GO:0042989	sequestering of actin monomers	1.198411e-2

GREAT analysis results for mouseGenomic Enrichment of Annotations Tool (GREAT, Nat Biotechnol. 2010 May;28(5):495-501) is used to identify, both in human and in mouse, the gene ontology terms of biological processes enriched given the predicted TFBSs, and evaluated the overlap in the top-500 gene ontology terms between human and mouse. For each novel motif, the P value for the overlap was then evaluated by calculating its relative rank with respect to this background distribution.<br>Analyst: Michiel de Hoon <br><br>link to source dataset <br>data

---

GO ID	GO Term	p-value
GO:0006890	retrograde vesicle-mediated transport, Golgi to ER	1.619685e-11
GO:0042339	keratan sulfate metabolic process	9.750005e-9
GO:0070358	actin polymerization-dependent cell motility	7.927815e-8
GO:0048193	Golgi vesicle transport	1.651008e-7
GO:0070060	'de novo' actin filament nucleation	1.700211e-7
GO:0001756	somitogenesis	2.027322e-7
GO:0051651	maintenance of location in cell	4.188541e-7
GO:0070079	histone H4-R3 demethylation	7.088974e-7
GO:0070078	histone H3-R2 demethylation	7.088974e-7
GO:0018192	enzyme active site formation via L-cysteine persulfide	7.088974e-7
GO:0018395	peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine	7.088974e-7
GO:0007219	Notch signaling pathway	1.003514e-6
GO:0090086	negative regulation of protein deubiquitination	1.014783e-6
GO:0034314	Arp2/3 complex-mediated actin nucleation	1.281601e-6
GO:0060683	regulation of branching involved in salivary gland morphogenesis by epithelial-mesenchymal signaling	2.217000e-6
GO:0032507	maintenance of protein location in cell	2.342871e-6
GO:0006928	cellular component movement	2.557292e-6
GO:0007020	microtubule nucleation	2.609751e-6
GO:0019344	cysteine biosynthetic process	2.756180e-6
GO:0006936	muscle contraction	3.425814e-6
GO:0061053	somite development	3.726259e-6
GO:0035814	negative regulation of renal sodium excretion	4.008385e-6
GO:0060427	lung connective tissue development	4.425294e-6
GO:0035269	protein O-linked mannosylation	8.301987e-6
GO:0051235	maintenance of location	9.571670e-6
GO:0000237	leptotene	1.146350e-5
GO:0031293	membrane protein intracellular domain proteolysis	1.332844e-5
GO:0018126	protein hydroxylation	1.437038e-5
GO:0045185	maintenance of protein location	1.714997e-5
GO:0090085	regulation of protein deubiquitination	2.391599e-5
GO:0090084	negative regulation of inclusion body assembly	2.391599e-5
GO:0043406	positive regulation of MAP kinase activity	2.692447e-5
GO:0009106	lipoate metabolic process	3.270334e-5
GO:0010458	exit from mitosis	3.467184e-5
GO:0060693	regulation of branching involved in salivary gland morphogenesis	3.484328e-5
GO:0042118	endothelial cell activation	3.815590e-5
GO:0048870	cell motility	3.907637e-5
GO:0048644	muscle organ morphogenesis	4.199665e-5
GO:0010512	negative regulation of phosphatidylinositol biosynthetic process	4.752753e-5
GO:0007621	negative regulation of female receptivity	4.764752e-5
GO:0007220	Notch receptor processing	5.341871e-5
GO:0048343	paraxial mesodermal cell fate commitment	5.767078e-5
GO:0019673	GDP-mannose metabolic process	5.870369e-5
GO:0042147	retrograde transport, endosome to Golgi	6.577356e-5
GO:0009107	lipoate biosynthetic process	6.713310e-5
GO:0050882	voluntary musculoskeletal movement	7.193927e-5
GO:0031581	hemidesmosome assembly	7.610502e-5
GO:0007041	lysosomal transport	8.121887e-5
GO:0003012	muscle system process	8.700504e-5
GO:0010511	regulation of phosphatidylinositol biosynthetic process	8.751198e-5
GO:0034453	microtubule anchoring	9.127439e-5
GO:0032060	bleb assembly	9.253117e-5
GO:0045188	regulation of circadian sleep/wake cycle, non-REM sleep	1.081449e-4
GO:0050901	leukocyte tethering or rolling	1.129117e-4
GO:0080164	regulation of nitric oxide metabolic process	1.174618e-4
GO:0016139	glycoside catabolic process	1.313225e-4
GO:0002642	positive regulation of immunoglobulin biosynthetic process	1.313225e-4
GO:0050881	musculoskeletal movement	1.447935e-4
GO:0019348	dolichol metabolic process	1.519919e-4
GO:0007258	JUN phosphorylation	1.585621e-4
GO:0042044	fluid transport	1.741412e-4
GO:0031023	microtubule organizing center organization	1.759581e-4
GO:0045820	negative regulation of glycolysis	1.795624e-4
GO:0046907	intracellular transport	2.043218e-4
GO:0006833	water transport	2.052979e-4
GO:0048333	mesodermal cell differentiation	2.187711e-4
GO:0034227	tRNA thio-modification	2.312575e-4
GO:0034498	early endosome to Golgi transport	2.342816e-4
GO:0006434	seryl-tRNA aminoacylation	2.342816e-4
GO:0051883	killing of cells in other organism involved in symbiotic interaction	2.777079e-4
GO:0031640	killing of cells of other organism	2.988854e-4
GO:0000097	sulfur amino acid biosynthetic process	3.018724e-4
GO:0006605	protein targeting	3.234784e-4
GO:0034113	heterotypic cell-cell adhesion	3.444355e-4
GO:0032808	lacrimal gland development	3.444704e-4
GO:0032915	positive regulation of transforming growth factor beta2 production	3.892762e-4
GO:0030970	retrograde protein transport, ER to cytosol	3.892762e-4
GO:0035793	positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway	3.906934e-4
GO:0019836	hemolysis by symbiont of host erythrocytes	3.923705e-4
GO:0001915	negative regulation of T cell mediated cytotoxicity	4.436225e-4
GO:0006012	galactose metabolic process	4.548470e-4
GO:0043654	recognition of apoptotic cell	4.691564e-4
GO:0035813	regulation of renal sodium excretion	4.801444e-4
GO:0060180	female mating behavior	4.820278e-4
GO:0035435	phosphate ion transmembrane transport	4.908925e-4
GO:0001692	histamine metabolic process	4.908925e-4
GO:0035282	segmentation	4.981012e-4
GO:0070861	regulation of protein exit from endoplasmic reticulum	5.331989e-4
GO:0071955	recycling endosome to Golgi transport	5.331989e-4
GO:0034499	late endosome to Golgi transport	5.331989e-4
GO:0030433	ER-associated protein catabolic process	5.350226e-4
GO:0060395	SMAD protein signal transduction	5.352584e-4
GO:0071284	cellular response to lead ion	5.603125e-4
GO:0048227	plasma membrane to endosome transport	5.603125e-4
GO:0018160	peptidyl-pyrromethane cofactor linkage	5.603125e-4
GO:0032298	positive regulation of DNA-dependent DNA replication initiation	5.603125e-4
GO:0043128	positive regulation of 1-phosphatidylinositol 4-kinase activity	5.603125e-4
GO:0016137	glycoside metabolic process	5.732993e-4
GO:0002098	tRNA wobble uridine modification	5.732993e-4
GO:0018198	peptidyl-cysteine modification	5.878431e-4
GO:0006886	intracellular protein transport	5.979384e-4
GO:0051188	cofactor biosynthetic process	6.220171e-4
GO:0016192	vesicle-mediated transport	6.453479e-4
GO:0031952	regulation of protein autophosphorylation	6.571104e-4
GO:0060621	negative regulation of cholesterol import	6.737578e-4
GO:0042249	establishment of planar polarity of embryonic epithelium	6.738071e-4
GO:0006983	ER overload response	6.811332e-4
GO:0048341	paraxial mesoderm formation	7.032460e-4
GO:0016477	cell migration	7.102750e-4
GO:0042987	amyloid precursor protein catabolic process	7.119359e-4
GO:0071673	positive regulation of smooth muscle cell chemotaxis	7.281040e-4
GO:0048034	heme O biosynthetic process	7.281040e-4
GO:0021870	Cajal-Retzius cell differentiation	7.523802e-4
GO:0071671	regulation of smooth muscle cell chemotaxis	7.523802e-4
GO:0051220	cytoplasmic sequestering of protein	7.643383e-4
GO:0031954	positive regulation of protein autophosphorylation	7.643383e-4
GO:0043405	regulation of MAP kinase activity	7.747973e-4
GO:0001946	lymphangiogenesis	7.815435e-4
GO:0050819	negative regulation of coagulation	7.939053e-4
GO:0050855	regulation of B cell receptor signaling pathway	8.245557e-4
GO:0010259	multicellular organismal aging	8.346229e-4
GO:0046010	positive regulation of circadian sleep/wake cycle, non-REM sleep	8.565896e-4
GO:0001911	negative regulation of leukocyte mediated cytotoxicity	9.182166e-4
GO:0051186	cofactor metabolic process	9.361730e-4
GO:0031468	nuclear envelope reassembly	9.578006e-4
GO:0007034	vacuolar transport	9.626054e-4
GO:0031342	negative regulation of cell killing	9.632639e-4
GO:0048646	anatomical structure formation involved in morphogenesis	9.669287e-4
GO:0016042	lipid catabolic process	1.034761e-3
GO:0042158	lipoprotein biosynthetic process	1.038083e-3
GO:0014034	neural crest cell fate commitment	1.058496e-3
GO:0090083	regulation of inclusion body assembly	1.099040e-3
GO:0060620	regulation of cholesterol import	1.099040e-3
GO:0030505	inorganic diphosphate transport	1.105803e-3
GO:0045924	regulation of female receptivity	1.108619e-3
GO:0007193	inhibition of adenylate cyclase activity by G-protein signaling pathway	1.131564e-3
GO:0048008	platelet-derived growth factor receptor signaling pathway	1.154401e-3
GO:0051597	response to methylmercury	1.166177e-3
GO:0014029	neural crest formation	1.232639e-3
GO:2000978	negative regulation of forebrain neuron differentiation	1.322578e-3
GO:2000227	negative regulation of pancreatic A cell differentiation	1.322578e-3
GO:0046331	lateral inhibition	1.322578e-3
GO:0061106	negative regulation of stomach neuroendocrine cell differentiation	1.322578e-3
GO:0070541	response to platinum ion	1.324642e-3
GO:0044062	regulation of excretion	1.352352e-3
GO:0007018	microtubule-based movement	1.363672e-3
GO:0002925	positive regulation of humoral immune response mediated by circulating immunoglobulin	1.407658e-3
GO:0010544	negative regulation of platelet activation	1.478432e-3
GO:0007224	smoothened signaling pathway	1.487944e-3
GO:0055108	Golgi to transport vesicle transport	1.496989e-3
GO:0044140	negative regulation of growth of symbiont on or near host surface	1.496989e-3
GO:0007032	endosome organization	1.534450e-3
GO:0002426	immunoglobulin production in mucosal tissue	1.537737e-3
GO:0071072	negative regulation of phospholipid biosynthetic process	1.537737e-3
GO:0003100	regulation of systemic arterial blood pressure by endothelin	1.569147e-3
GO:0061072	iris morphogenesis	1.592595e-3
GO:0042628	mating plug formation	1.592595e-3
GO:0006481	C-terminal protein methylation	1.606713e-3
GO:0006777	Mo-molybdopterin cofactor biosynthetic process	1.621346e-3
GO:0035335	peptidyl-tyrosine dephosphorylation	1.648278e-3
GO:0007509	mesoderm migration involved in gastrulation	1.710797e-3
GO:0044272	sulfur compound biosynthetic process	1.730773e-3
GO:0006022	aminoglycan metabolic process	1.751301e-3
GO:0010543	regulation of platelet activation	1.761335e-3
GO:2000059	negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process	1.809635e-3
GO:0032239	regulation of nucleobase-containing compound transport	1.847874e-3
GO:0001710	mesodermal cell fate commitment	1.877933e-3
GO:0034613	cellular protein localization	1.921154e-3
GO:0050818	regulation of coagulation	1.921526e-3
GO:0001914	regulation of T cell mediated cytotoxicity	1.954902e-3
GO:0051129	negative regulation of cellular component organization	1.974723e-3
GO:0001916	positive regulation of T cell mediated cytotoxicity	2.069151e-3
GO:0071071	regulation of phospholipid biosynthetic process	2.101986e-3
GO:0015705	iodide transport	2.161152e-3
GO:0070727	cellular macromolecule localization	2.189867e-3
GO:0032900	negative regulation of neurotrophin production	2.193562e-3
GO:0032244	positive regulation of nucleoside transport	2.193562e-3
GO:0070936	protein K48-linked ubiquitination	2.330884e-3
GO:0048304	positive regulation of isotype switching to IgG isotypes	2.390631e-3
GO:0007159	leukocyte cell-cell adhesion	2.463754e-3
GO:0021558	trochlear nerve development	2.511397e-3
GO:0019098	reproductive behavior	2.548073e-3
GO:0006497	protein lipidation	2.560863e-3
GO:0042074	cell migration involved in gastrulation	2.667071e-3
GO:0046640	regulation of alpha-beta T cell proliferation	2.759630e-3
GO:0009108	coenzyme biosynthetic process	2.783575e-3
GO:0060434	bronchus morphogenesis	2.901035e-3
GO:0035166	post-embryonic hemopoiesis	2.901035e-3
GO:0045608	negative regulation of auditory receptor cell differentiation	2.901035e-3
GO:0043268	positive regulation of potassium ion transport	2.908090e-3
GO:0023019	signal transduction involved in regulation of gene expression	2.956925e-3
GO:0042157	lipoprotein metabolic process	2.959177e-3
GO:0048505	regulation of timing of cell differentiation	2.978408e-3
GO:0002820	negative regulation of adaptive immune response	3.061067e-3
GO:0051775	response to redox state	3.061322e-3
GO:0006499	N-terminal protein myristoylation	3.061322e-3
GO:0016311	dephosphorylation	3.186509e-3
GO:0007194	negative regulation of adenylate cyclase activity	3.190967e-3
GO:0070995	NADPH oxidation	3.247139e-3
GO:0050951	sensory perception of temperature stimulus	3.247139e-3
GO:0019363	pyridine nucleotide biosynthetic process	3.313364e-3
GO:0060684	epithelial-mesenchymal cell signaling	3.458201e-3
GO:0002040	sprouting angiogenesis	3.542491e-3
GO:0002475	antigen processing and presentation via MHC class Ib	3.614765e-3
GO:0045833	negative regulation of lipid metabolic process	3.627107e-3
GO:0032682	negative regulation of chemokine production	3.659344e-3
GO:0001667	ameboidal cell migration	3.667544e-3
GO:0060613	fat pad development	3.697817e-3
GO:0021860	pyramidal neuron development	3.734455e-3
GO:0048710	regulation of astrocyte differentiation	3.850746e-3
GO:0002768	immune response-regulating cell surface receptor signaling pathway	3.866666e-3
GO:0060059	embryonic retina morphogenesis in camera-type eye	3.889121e-3
GO:0006732	coenzyme metabolic process	3.997297e-3
GO:0045010	actin nucleation	4.012390e-3
GO:0008078	mesodermal cell migration	4.012390e-3
GO:0040034	regulation of development, heterochronic	4.074442e-3
GO:0060606	tube closure	4.090810e-3
GO:0021861	forebrain radial glial cell differentiation	4.130018e-3
GO:0045123	cellular extravasation	4.278132e-3
GO:0050857	positive regulation of antigen receptor-mediated signaling pathway	4.285078e-3
GO:0042660	positive regulation of cell fate specification	4.363444e-3
GO:0070869	heterochromatin formation involved in chromatin silencing	4.363444e-3
GO:0006978	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator	4.382533e-3
GO:0060075	regulation of resting membrane potential	4.441444e-3
GO:0003009	skeletal muscle contraction	4.515302e-3
GO:0048339	paraxial mesoderm development	4.601700e-3
GO:0006493	protein O-linked glycosylation	4.601700e-3
GO:0006534	cysteine metabolic process	4.666296e-3
GO:0001843	neural tube closure	4.667242e-3
GO:0002710	negative regulation of T cell mediated immunity	4.732490e-3
GO:0010043	response to zinc ion	4.782238e-3
GO:0045938	positive regulation of circadian sleep/wake cycle, sleep	4.922558e-3
GO:0006200	ATP catabolic process	4.935199e-3
GO:0021797	forebrain anterior/posterior pattern specification	5.013480e-3
GO:0050732	negative regulation of peptidyl-tyrosine phosphorylation	5.189293e-3
GO:0051817	modification of morphology or physiology of other organism involved in symbiotic interaction	5.190182e-3
GO:0044242	cellular lipid catabolic process	5.230070e-3
GO:0051482	elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger	5.243365e-3
GO:0033058	directional locomotion	5.275014e-3
GO:0072141	renal interstitial cell development	5.525059e-3
GO:0009792	embryo development ending in birth or egg hatching	5.538067e-3
GO:0001988	positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure	5.565292e-3
GO:0010793	regulation of mRNA export from nucleus	5.565292e-3
GO:0060112	generation of ovulation cycle rhythm	5.565292e-3
GO:0006742	NADP catabolic process	5.565292e-3
GO:0051641	cellular localization	5.598120e-3
GO:0045588	positive regulation of gamma-delta T cell differentiation	5.765805e-3
GO:0014829	vascular smooth muscle contraction	5.933316e-3
GO:0040011	locomotion	5.970489e-3
GO:0060356	leucine import	6.033584e-3
GO:0033057	multicellular organismal reproductive behavior	6.163184e-3
GO:0050965	detection of temperature stimulus involved in sensory perception of pain	6.201811e-3
GO:0072215	regulation of metanephros development	6.468582e-3
GO:0006750	glutathione biosynthetic process	6.691147e-3
GO:0016577	histone demethylation	6.698967e-3
GO:0046477	glycosylceramide catabolic process	6.934680e-3
GO:0045590	negative regulation of regulatory T cell differentiation	7.008267e-3
GO:0021915	neural tube development	7.134203e-3
GO:0005976	polysaccharide metabolic process	7.285606e-3
GO:0060997	dendritic spine morphogenesis	7.528127e-3
GO:0007517	muscle organ development	7.606781e-3
GO:0006622	protein targeting to lysosome	7.628518e-3
GO:0006032	chitin catabolic process	7.725932e-3
GO:0061034	olfactory bulb mitral cell layer development	7.725932e-3
GO:0042772	DNA damage response, signal transduction resulting in transcription	8.038599e-3
GO:0042753	positive regulation of circadian rhythm	8.038599e-3
GO:0090161	Golgi ribbon formation	8.081443e-3
GO:0051639	actin filament network formation	8.081443e-3
GO:0045187	regulation of circadian sleep/wake cycle, sleep	8.256697e-3
GO:0048066	developmental pigmentation	8.334486e-3
GO:0042982	amyloid precursor protein metabolic process	8.427159e-3
GO:0046103	inosine biosynthetic process	8.461115e-3
GO:0051177	meiotic sister chromatid cohesion	8.461115e-3
GO:0006154	adenosine catabolic process	8.461115e-3
GO:0032241	positive regulation of nucleobase-containing compound transport	8.461115e-3
GO:0022029	telencephalon cell migration	8.537837e-3
GO:0002381	immunoglobulin production involved in immunoglobulin mediated immune response	8.553089e-3
GO:0097150	neuronal stem cell maintenance	8.577785e-3
GO:0045908	negative regulation of vasodilation	8.577785e-3
GO:0043009	chordate embryonic development	8.621295e-3
GO:0071902	positive regulation of protein serine/threonine kinase activity	8.627529e-3
GO:0060019	radial glial cell differentiation	8.652303e-3
GO:0060665	regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling	8.910148e-3
GO:0014020	primary neural tube formation	8.916820e-3
GO:0046641	positive regulation of alpha-beta T cell proliferation	9.025488e-3
GO:0002891	positive regulation of immunoglobulin mediated immune response	9.025488e-3
GO:0090104	pancreatic E cell differentiation	9.084274e-3
GO:0060629	regulation of homologous chromosome segregation	9.084274e-3
GO:0071105	response to interleukin-11	9.084274e-3
GO:0003311	pancreatic D cell differentiation	9.084274e-3
GO:0046079	dUMP catabolic process	9.084274e-3
GO:0051598	meiotic recombination checkpoint	9.084274e-3
GO:0002285	lymphocyte activation involved in immune response	9.125175e-3
GO:0051209	release of sequestered calcium ion into cytosol	9.125187e-3
GO:0070933	histone H4 deacetylation	9.177064e-3
GO:0003339	regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis	9.177064e-3
GO:0006784	heme a biosynthetic process	9.256897e-3
GO:0030203	glycosaminoglycan metabolic process	9.398193e-3
GO:0019853	L-ascorbic acid biosynthetic process	9.451139e-3
GO:0006482	protein demethylation	9.496555e-3
GO:0061061	muscle structure development	9.734052e-3
GO:0045685	regulation of glial cell differentiation	9.765071e-3
GO:0071236	cellular response to antibiotic	9.832123e-3
GO:0016090	prenol metabolic process	9.953133e-3
GO:0060541	respiratory system development	1.013913e-2
GO:0042098	T cell proliferation	1.017835e-2
GO:0060649	mammary gland bud elongation	1.033428e-2
GO:0060659	nipple sheath formation	1.033428e-2
GO:0032765	positive regulation of mast cell cytokine production	1.033428e-2
GO:0002431	Fc receptor mediated stimulatory signaling pathway	1.033428e-2
GO:0002286	T cell activation involved in immune response	1.043248e-2
GO:0045607	regulation of auditory receptor cell differentiation	1.047188e-2
GO:0044154	histone H3-K14 acetylation	1.053819e-2
GO:0002651	positive regulation of tolerance induction to self antigen	1.053819e-2
GO:0046888	negative regulation of hormone secretion	1.055695e-2
GO:0006783	heme biosynthetic process	1.065558e-2
GO:0042745	circadian sleep/wake cycle	1.071171e-2
GO:0002709	regulation of T cell mediated immunity	1.076084e-2
GO:0006548	histidine catabolic process	1.077472e-2
GO:0030240	skeletal muscle thin filament assembly	1.083583e-2
GO:0014821	phasic smooth muscle contraction	1.085799e-2
GO:0051054	positive regulation of DNA metabolic process	1.095274e-2
GO:0044003	modification by symbiont of host morphology or physiology	1.100237e-2
GO:0048302	regulation of isotype switching to IgG isotypes	1.110285e-2
GO:0007274	neuromuscular synaptic transmission	1.110285e-2
GO:0034375	high-density lipoprotein particle remodeling	1.134652e-2
GO:0060192	negative regulation of lipase activity	1.136590e-2
GO:0042149	cellular response to glucose starvation	1.136590e-2
GO:0071548	response to dexamethasone stimulus	1.151998e-2
GO:0021532	neural tube patterning	1.168397e-2
GO:0015827	tryptophan transport	1.192864e-2
GO:0002923	regulation of humoral immune response mediated by circulating immunoglobulin	1.204065e-2
GO:0009912	auditory receptor cell fate commitment	1.222574e-2
GO:0009635	response to herbicide	1.235107e-2
GO:2000224	regulation of testosterone biosynthetic process	1.242844e-2
GO:0015759	beta-glucoside transport	1.242844e-2
GO:0060695	negative regulation of cholesterol transporter activity	1.242844e-2
GO:0046102	inosine metabolic process	1.242844e-2
GO:0019509	L-methionine salvage from methylthioadenosine	1.242844e-2
GO:0032715	negative regulation of interleukin-6 production	1.246978e-2
GO:0001542	ovulation from ovarian follicle	1.246978e-2
GO:0046503	glycerolipid catabolic process	1.260345e-2
GO:0051179	localization	1.262208e-2
GO:0045416	positive regulation of interleukin-8 biosynthetic process	1.263352e-2
GO:0050853	B cell receptor signaling pathway	1.269273e-2
GO:0043056	forward locomotion	1.291307e-2
GO:0007618	mating	1.307200e-2
GO:0030011	maintenance of cell polarity	1.316616e-2
GO:0021885	forebrain cell migration	1.323756e-2
GO:0045872	positive regulation of rhodopsin gene expression	1.334625e-2
GO:0007624	ultradian rhythm	1.334625e-2
GO:0009159	deoxyribonucleoside monophosphate catabolic process	1.334625e-2
GO:0045830	positive regulation of isotype switching	1.342825e-2
GO:0021904	dorsal/ventral neural tube patterning	1.342825e-2
GO:0006278	RNA-dependent DNA replication	1.342825e-2
GO:0046340	diacylglycerol catabolic process	1.343133e-2
GO:0071918	urea transmembrane transport	1.343133e-2
GO:0030046	parallel actin filament bundle assembly	1.343133e-2
GO:0010963	regulation of L-arginine import	1.343133e-2
GO:0015722	canalicular bile acid transport	1.343133e-2
GO:0021589	cerebellum structural organization	1.343133e-2
GO:0006547	histidine metabolic process	1.352573e-2
GO:0002711	positive regulation of T cell mediated immunity	1.361828e-2
GO:2000981	negative regulation of inner ear receptor cell differentiation	1.381955e-2
GO:0060415	muscle tissue morphogenesis	1.385383e-2
GO:0042454	ribonucleoside catabolic process	1.401910e-2
GO:0014866	skeletal myofibril assembly	1.404504e-2
GO:0060537	muscle tissue development	1.413073e-2
GO:0050730	regulation of peptidyl-tyrosine phosphorylation	1.438151e-2
GO:0031100	organ regeneration	1.445275e-2
GO:0050995	negative regulation of lipid catabolic process	1.465087e-2
GO:0051771	negative regulation of nitric-oxide synthase biosynthetic process	1.474739e-2
GO:0070256	negative regulation of mucus secretion	1.474739e-2
GO:0015889	cobalamin transport	1.474739e-2
GO:0042323	negative regulation of circadian sleep/wake cycle, non-REM sleep	1.474739e-2
GO:0042668	auditory receptor cell fate determination	1.507817e-2
GO:0002429	immune response-activating cell surface receptor signaling pathway	1.524289e-2
GO:0060996	dendritic spine development	1.525047e-2
GO:0003016	respiratory system process	1.525047e-2
GO:0000186	activation of MAPKK activity	1.527192e-2
GO:0006470	protein dephosphorylation	1.570859e-2
GO:0009895	negative regulation of catabolic process	1.579921e-2
GO:0000096	sulfur amino acid metabolic process	1.607183e-2
GO:0010842	retina layer formation	1.608440e-2
GO:0045860	positive regulation of protein kinase activity	1.621911e-2
GO:0003007	heart morphogenesis	1.629863e-2
GO:0042100	B cell proliferation	1.633026e-2
GO:0016197	endosome transport	1.640753e-2
GO:0006030	chitin metabolic process	1.641112e-2
GO:0051895	negative regulation of focal adhesion assembly	1.641112e-2
GO:0030833	regulation of actin filament polymerization	1.641326e-2
GO:0010042	response to manganese ion	1.653158e-2
GO:0006621	protein retention in ER lumen	1.673264e-2
GO:0048664	neuron fate determination	1.673264e-2
GO:0030318	melanocyte differentiation	1.675790e-2
GO:0010987	negative regulation of high-density lipoprotein particle clearance	1.678454e-2
GO:0010897	negative regulation of triglyceride catabolic process	1.678454e-2
GO:0010761	fibroblast migration	1.703134e-2
GO:0008333	endosome to lysosome transport	1.720158e-2
GO:0033490	cholesterol biosynthetic process via lathosterol	1.729383e-2
GO:0030174	regulation of DNA-dependent DNA replication initiation	1.729383e-2
GO:0010994	free ubiquitin chain polymerization	1.729383e-2
GO:0002476	antigen processing and presentation of endogenous peptide antigen via MHC class Ib	1.729383e-2
GO:0002244	hemopoietic progenitor cell differentiation	1.769508e-2
GO:0046464	acylglycerol catabolic process	1.771482e-2
GO:0070252	actin-mediated cell contraction	1.771482e-2
GO:0051048	negative regulation of secretion	1.780571e-2
GO:0016048	detection of temperature stimulus	1.782007e-2
GO:0014826	vein smooth muscle contraction	1.782007e-2
GO:0051138	positive regulation of NK T cell differentiation	1.782705e-2
GO:0046034	ATP metabolic process	1.819588e-2
GO:0033313	meiotic cell cycle checkpoint	1.830164e-2
GO:0042138	meiotic DNA double-strand break formation	1.830164e-2
GO:0032853	positive regulation of Ran GTPase activity	1.830164e-2
GO:0010189	vitamin E biosynthetic process	1.830164e-2
GO:0014823	response to activity	1.838973e-2
GO:0035304	regulation of protein dephosphorylation	1.860199e-2
GO:0014706	striated muscle tissue development	1.861462e-2
GO:0017004	cytochrome complex assembly	1.863999e-2
GO:0030832	regulation of actin filament length	1.864809e-2
GO:0002707	negative regulation of lymphocyte mediated immunity	1.874990e-2
GO:0051282	regulation of sequestering of calcium ion	1.877883e-2
GO:0071425	hemopoietic stem cell proliferation	1.878318e-2
GO:0090209	negative regulation of triglyceride metabolic process	1.888232e-2
GO:0051414	response to cortisol stimulus	1.899921e-2
GO:0012501	programmed cell death	1.909899e-2
GO:0003002	regionalization	1.911941e-2
GO:0007094	mitotic cell cycle spindle assembly checkpoint	1.930658e-2
GO:0008050	female courtship behavior	1.930658e-2
GO:0002649	regulation of tolerance induction to self antigen	1.930658e-2
GO:0022410	circadian sleep/wake cycle process	1.969144e-2
GO:0019377	glycolipid catabolic process	1.975054e-2
GO:0002906	negative regulation of mature B cell apoptosis	1.975054e-2
GO:0009070	serine family amino acid biosynthetic process	1.975054e-2
GO:0050931	pigment cell differentiation	1.981169e-2
GO:0034067	protein localization in Golgi apparatus	1.998055e-2
GO:0043376	regulation of CD8-positive, alpha-beta T cell differentiation	2.006954e-2
GO:0042946	glucoside transport	2.006954e-2
GO:0006498	N-terminal protein lipidation	2.006954e-2
GO:0050854	regulation of antigen receptor-mediated signaling pathway	2.041785e-2
GO:0009435	NAD biosynthetic process	2.042743e-2
GO:0017183	peptidyl-diphthamide biosynthetic process from peptidyl-histidine	2.061756e-2
GO:0002175	protein localization to paranode region of axon	2.061756e-2
GO:0001657	ureteric bud development	2.075383e-2
GO:0071549	cellular response to dexamethasone stimulus	2.085861e-2
GO:0008340	determination of adult lifespan	2.085861e-2
GO:0071174	mitotic cell cycle spindle checkpoint	2.087215e-2
GO:0015871	choline transport	2.087215e-2
GO:0048738	cardiac muscle tissue development	2.103737e-2
GO:0033275	actin-myosin filament sliding	2.104082e-2
GO:0033674	positive regulation of kinase activity	2.105743e-2
GO:0045911	positive regulation of DNA recombination	2.110007e-2
GO:0007259	JAK-STAT cascade	2.148989e-2
GO:0070988	demethylation	2.148989e-2
GO:0051659	maintenance of mitochondrion location	2.164719e-2
GO:0070050	neuron homeostasis	2.177256e-2
GO:0050435	beta-amyloid metabolic process	2.177256e-2
GO:0051103	DNA ligation involved in DNA repair	2.177256e-2
GO:0033198	response to ATP	2.180277e-2
GO:0061384	heart trabecular morphogenesis	2.187542e-2
GO:0032943	mononuclear cell proliferation	2.201922e-2
GO:0030324	lung development	2.206165e-2
GO:0030195	negative regulation of blood coagulation	2.247087e-2
GO:0051563	smooth endoplasmic reticulum calcium ion homeostasis	2.251817e-2
GO:0007031	peroxisome organization	2.252275e-2
GO:0035121	tail morphogenesis	2.264916e-2
GO:0015760	glucose-6-phosphate transport	2.271910e-2
GO:0000165	MAPKKK cascade	2.279540e-2
GO:0006915	apoptosis	2.282933e-2
GO:0070372	regulation of ERK1 and ERK2 cascade	2.286387e-2
GO:0048387	negative regulation of retinoic acid receptor signaling pathway	2.286449e-2
GO:0044337	canonical Wnt receptor signaling pathway involved in positive regulation of apoptosis	2.307538e-2
GO:0031247	actin rod assembly	2.307538e-2
GO:0018065	protein-cofactor linkage	2.307538e-2
GO:2000974	negative regulation of pro-B cell differentiation	2.317616e-2
GO:0070373	negative regulation of ERK1 and ERK2 cascade	2.326023e-2
GO:0009952	anterior/posterior pattern specification	2.336794e-2
GO:0060433	bronchus development	2.354075e-2
GO:0001906	cell killing	2.356925e-2
GO:0033036	macromolecule localization	2.386622e-2
GO:0021932	hindbrain radial glia guided cell migration	2.397505e-2
GO:0002922	positive regulation of humoral immune response	2.401546e-2
GO:0007044	cell-substrate junction assembly	2.411019e-2
GO:0043090	amino acid import	2.417240e-2
GO:0006509	membrane protein ectodomain proteolysis	2.424512e-2
GO:0000733	DNA strand renaturation	2.424594e-2
GO:0018410	C-terminal protein amino acid modification	2.424594e-2
GO:0051645	Golgi localization	2.463917e-2
GO:0072050	S-shaped body morphogenesis	2.481847e-2
GO:0072049	comma-shaped body morphogenesis	2.481847e-2
GO:0021912	regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification	2.494622e-2
GO:0007216	metabotropic glutamate receptor signaling pathway	2.494622e-2
GO:0007175	negative regulation of epidermal growth factor-activated receptor activity	2.512285e-2
GO:0001910	regulation of leukocyte mediated cytotoxicity	2.512427e-2
GO:0006516	glycoprotein catabolic process	2.569035e-2
GO:0045742	positive regulation of epidermal growth factor receptor signaling pathway	2.596571e-2
GO:0030323	respiratory tube development	2.604267e-2
GO:0071286	cellular response to magnesium ion	2.605669e-2
GO:0030593	neutrophil chemotaxis	2.621979e-2
GO:0021813	cell-cell adhesion involved in neuronal-glial interactions involved in cerebral cortex radial glia guided migration	2.631138e-2