MCL coexpression mm9:800

Phase1 CAGE Peaks

	Short description
Mm9::chr11:95703982..95704018,+	p2@Gngt2
Mm9::chr11:95704020..95704035,+	p5@Gngt2
Mm9::chr15:75427054..75427073,+	p2@Gpihbp1
Mm9::chr15:75427075..75427092,+	p1@Gpihbp1
Mm9::chr18:61799257..61799286,+	p1@LOC545261
Mm9::chr2:3031492..3031497,+	p3@Fam171a1
Mm9::chr6:3954185..3954196,+	p4@Gng11
Mm9::chr9:122026456..122026485,+	p2@Snrk
Mm9::chr9:122026498..122026509,+	p3@Snrk

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0005834	heterotrimeric G-protein complex	0.00136621449799453
GO:0019897	extrinsic to plasma membrane	0.00158289096160373
GO:0019898	extrinsic to membrane	0.00201812338159081
GO:0008035	high-density lipoprotein binding	0.0118317262005294
GO:0044459	plasma membrane part	0.0247739886635087
GO:0031225	anchored to membrane	0.0247739886635087
GO:0046658	anchored to plasma membrane	0.0247739886635087
GO:0008034	lipoprotein binding	0.0256143454205485
GO:0005886	plasma membrane	0.0328245037506178

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>

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Uber Anatomy

Ontology term	p-value	n
trunk region element	3.41e-18	79
subdivision of trunk	5.89e-16	66
trunk	6.95e-14	90
abdomen element	9.49e-12	49
abdominal segment element	9.49e-12	49
abdominal segment of trunk	9.49e-12	49
abdomen	9.49e-12	49
multi-cellular organism	1.22e-08	333
immaterial anatomical entity	1.41e-08	79
lung	8.26e-08	14
respiratory tube	8.26e-08	14
respiration organ	8.26e-08	14
pair of lungs	8.26e-08	14
lung primordium	8.26e-08	14
lung bud	8.26e-08	14
organism subdivision	1.00e-07	150
splanchnic layer of lateral plate mesoderm	1.31e-07	33
epithelial bud	1.32e-07	17
epithelial tube	1.59e-07	47

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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