MCL coexpression mm9:517

Phase1 CAGE Peaks

	Short description
Mm9::chr10:75905161..75905170,+	p@chr10:75905161..75905170 +
Mm9::chr11:40506276..40506304,+	p@chr11:40506276..40506304 +
Mm9::chr11:74645494..74645512,-	p@chr11:74645494..74645512 -
Mm9::chr13:17897362..17897374,+	p@chr13:17897362..17897374 +
Mm9::chr18:80666897..80666910,+	p@chr18:80666897..80666910 +
Mm9::chr1:180336546..180336570,-	p@chr1:180336546..180336570 -
Mm9::chr1:55084441..55084444,+	p@chr1:55084441..55084444 +
Mm9::chr3:151873231..151873284,-	p2@Dnajb4
Mm9::chr3:94819682..94819707,+	p2@ENSMUST00000128160
Mm9::chr5:135485177..135485187,+	p10@Abhd11
Mm9::chr7:19857297..19857302,+	p@chr7:19857297..19857302 +
Mm9::chr8:47637081..47637096,-	p@chr8:47637081..47637096 -
Mm9::chr8:87187820..87187854,-	p@chr8:87187820..87187854 -
Mm9::chr9:61219994..61220018,-	p1@Gm10655

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0031072	heat shock protein binding	0.0380711781619535
GO:0051082	unfolded protein binding	0.0380711781619535
GO:0006725	aromatic compound metabolic process	0.0425816901190811
GO:0006457	protein folding	0.0425816901190811

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>

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Cell Type

Ontology term	p-value	n
hematopoietic cell	1.38e-11	32
hematopoietic oligopotent progenitor cell	1.38e-11	32
hematopoietic stem cell	1.38e-11	32
angioblastic mesenchymal cell	1.38e-11	32
hematopoietic multipotent progenitor cell	1.38e-11	32
connective tissue cell	2.85e-09	46
mesenchymal cell	2.85e-09	46
hematopoietic lineage restricted progenitor cell	2.10e-08	25
lymphoid lineage restricted progenitor cell	4.11e-08	12
lymphocyte	4.30e-08	13
common lymphoid progenitor	4.30e-08	13
nucleate cell	6.81e-08	16
leukocyte	9.20e-08	17
nongranular leukocyte	9.20e-08	17
T cell	1.69e-07	11
pro-T cell	1.69e-07	11

Uber Anatomy

Ontology term	p-value	n
connective tissue	2.85e-09	46
simple columnar epithelium	1.82e-07	11

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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