MCL coexpression mm9:402

Phase1 CAGE Peaks

	Short description
Mm9::chr12:112053229..112053257,-	p@chr12:112053229..112053257 -
Mm9::chr14:55612521..55612532,-	p@chr14:55612521..55612532 -
Mm9::chr14:79534980..79534984,-	p@chr14:79534980..79534984 -
Mm9::chr15:11650313..11650319,-	p@chr15:11650313..11650319 -
Mm9::chr16:11447398..11447407,+	p5@Snx29
Mm9::chr16:58622730..58622745,+	p@chr16:58622730..58622745 +
Mm9::chr19:6915351..6915368,-	p3@Rps6ka4
Mm9::chr1:193289202..193289222,-	p@chr1:193289202..193289222 -
Mm9::chr1:74672878..74672903,+	p4@Stk36
Mm9::chr2:167703096..167703112,-	p@chr2:167703096..167703112 -
Mm9::chr4:138813018..138813038,+	p@chr4:138813018..138813038 +
Mm9::chr6:121135474..121135489,+	p@chr6:121135474..121135489 +
Mm9::chr7:139462080..139462102,-	p@chr7:139462080..139462102 -
Mm9::chr7:56389644..56389651,-	p@chr7:56389644..56389651 -
Mm9::chr8:12826193..12826215,+	p@chr8:12826193..12826215 +
Mm9::chr8:90952630..90952639,+	p@chr8:90952630..90952639 +
Mm9::chr8:90952677..90952689,+	p@chr8:90952677..90952689 +
Mm9::chr8:90952709..90952722,+	p@chr8:90952709..90952722 +
Mm9::chr8:90952775..90952800,+	p@chr8:90952775..90952800 +

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0005524	ATP binding	0.00865956442285859
GO:0032559	adenyl ribonucleotide binding	0.00865956442285859
GO:0030554	adenyl nucleotide binding	0.00865956442285859
GO:0032553	ribonucleotide binding	0.00865956442285859
GO:0032555	purine ribonucleotide binding	0.00865956442285859
GO:0017076	purine nucleotide binding	0.00865956442285859
GO:0000166	nucleotide binding	0.0107813422052218
GO:0004674	protein serine/threonine kinase activity	0.0141489964699634
GO:0032982	myosin filament	0.0156774074596713
GO:0005863	striated muscle thick filament	0.0156774074596713
GO:0005859	muscle myosin complex	0.0156774074596713
GO:0016460	myosin II complex	0.0162142769304795
GO:0004672	protein kinase activity	0.0162142769304795
GO:0006468	protein amino acid phosphorylation	0.0165141795883867
GO:0016773	phosphotransferase activity, alcohol group as acceptor	0.017971366889255
GO:0016310	phosphorylation	0.017971366889255
GO:0006941	striated muscle contraction	0.0200360524631142
GO:0009791	post-embryonic development	0.0200360524631142
GO:0006793	phosphorus metabolic process	0.0200360524631142
GO:0006796	phosphate metabolic process	0.0200360524631142
GO:0016301	kinase activity	0.0222815721268089
GO:0016772	transferase activity, transferring phosphorus-containing groups	0.0277214315621512
GO:0016459	myosin complex	0.0304552447940586
GO:0030017	sarcomere	0.0337779570497254
GO:0044449	contractile fiber part	0.0338952074532296
GO:0030016	myofibril	0.0339509920293152
GO:0043292	contractile fiber	0.0339509920293152
GO:0043687	post-translational protein modification	0.0339509920293152
GO:0003012	muscle system process	0.0339509920293152
GO:0006936	muscle contraction	0.0339509920293152
GO:0005516	calmodulin binding	0.0411566028369654
GO:0006464	protein modification process	0.0411566028369654
GO:0043412	biopolymer modification	0.0429372073283632

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>

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Uber Anatomy

Ontology term	p-value	n
lung	4.16e-20	14
respiratory tube	4.16e-20	14
respiration organ	4.16e-20	14
pair of lungs	4.16e-20	14
lung primordium	4.16e-20	14
lung bud	4.16e-20	14
epithelial bud	4.07e-16	17
thoracic cavity element	4.07e-16	17
thoracic segment organ	4.07e-16	17
thoracic cavity	4.07e-16	17
thoracic segment of trunk	4.07e-16	17
respiratory primordium	4.07e-16	17
endoderm of foregut	4.07e-16	17
epithelial fold	2.52e-13	20

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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