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Coexpression cluster:C790: Difference between revisions

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|gostat_on_coexpression_clusters=GO:0015020!glucuronosyltransferase activity!0.0100082420817144!167127$GO:0008194!UDP-glycosyltransferase activity!0.0203108442246556!167127$GO:0016758!transferase activity, transferring hexosyl groups!0.0275717257349189!167127$GO:0016757!transferase activity, transferring glycosyl groups!0.0326003767808784!167127
|gostat_on_coexpression_clusters=GO:0015020!glucuronosyltransferase activity!0.0100082420817144!167127$GO:0008194!UDP-glycosyltransferase activity!0.0203108442246556!167127$GO:0016758!transferase activity, transferring hexosyl groups!0.0275717257349189!167127$GO:0016757!transferase activity, transferring glycosyl groups!0.0326003767808784!167127
|id=C790
|id=C790
|ontology_enrichment_celltype=CL:0000147!3.37e-07!14
|ontology_enrichment_celltype=
|ontology_enrichment_disease=DOID:0050687!1.39e-10!143;DOID:3095!5.11e-08!22;DOID:2994!5.11e-08!22;DOID:305!4.20e-07!106
|ontology_enrichment_disease=DOID:171!1.56e-74!10;DOID:3095!8.77e-34!22;DOID:2994!8.77e-34!22;DOID:169!1.83e-23!6;DOID:3193!4.70e-09!2;DOID:962!4.70e-09!2
|ontology_enrichment_uberon=UBERON:0000073!1.38e-17!94;UBERON:0001016!1.38e-17!94;UBERON:0002346!2.95e-17!90;UBERON:0005743!1.26e-15!86;UBERON:0000924!1.38e-15!173;UBERON:0006601!1.38e-15!173;UBERON:0003075!9.45e-15!86;UBERON:0007284!9.45e-15!86;UBERON:0001017!8.07e-14!82;UBERON:0004121!1.34e-13!169;UBERON:0001049!3.60e-13!57;UBERON:0005068!3.60e-13!57;UBERON:0006241!3.60e-13!57;UBERON:0007135!3.60e-13!57;UBERON:0003056!7.57e-12!61;UBERON:0007023!1.07e-11!115;UBERON:0002780!1.80e-11!41;UBERON:0001890!1.80e-11!41;UBERON:0006240!1.80e-11!41;UBERON:0003080!6.63e-11!42;UBERON:0002616!9.90e-11!59;UBERON:0002020!2.15e-09!34;UBERON:0003528!2.15e-09!34;UBERON:0000955!2.70e-09!69;UBERON:0006238!2.70e-09!69;UBERON:0001893!2.87e-09!34;UBERON:0002791!6.47e-09!33;UBERON:0001869!1.31e-08!32;UBERON:0001950!4.83e-08!20;UBERON:0000956!5.31e-08!25;UBERON:0000203!5.31e-08!25;UBERON:0002619!7.54e-08!22;UBERON:0000153!3.48e-07!129;UBERON:0007811!3.48e-07!129;UBERON:0000033!8.41e-07!123
|ontology_enrichment_uberon=UBERON:0000013!5.30e-28!5;UBERON:0002410!5.30e-28!5;UBERON:0001301!1.65e-16!1;UBERON:0001882!3.07e-16!1;UBERON:0005403!3.07e-16!1;UBERON:0000010!7.01e-16!8;UBERON:0003714!4.70e-09!2;UBERON:0002771!5.94e-09!2;UBERON:0002346!3.52e-08!86;UBERON:0004121!7.63e-08!171;UBERON:0000924!7.63e-08!171;UBERON:0006601!7.63e-08!171
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}}
}}

Revision as of 16:43, 19 October 2012


Full id: C790_neuroectodermal_carcinoid_neuroblastoma_neuroepithelioma_acute_peripheral_granulocyte



Phase1 CAGE Peaks

Hg19::chr11:110225996..110226016,+p2@ENST00000526703
Hg19::chr11:110226020..110226044,+p1@ENST00000526703
Hg19::chr1:60312301..60312314,+p@chr1:60312301..60312314
+
Hg19::chr1:60314016..60314043,+p@chr1:60314016..60314043
+
Hg19::chr3:131266295..131266298,-p@chr3:131266295..131266298
-
Hg19::chr3:131520725..131520729,-p@chr3:131520725..131520729
-
Hg19::chr3:5932149..5932178,+p@chr3:5932149..5932178
+
Hg19::chr3:6163135..6163137,+p@chr3:6163135..6163137
+
Hg19::chr5:36066975..36067019,-p1@UGT3A2
Hg19::chr9:15980752..15980757,+p@chr9:15980752..15980757
+


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0015020glucuronosyltransferase activity0.0100082420817144
GO:0008194UDP-glycosyltransferase activity0.0203108442246556
GO:0016758transferase activity, transferring hexosyl groups0.0275717257349189
GO:0016757transferase activity, transferring glycosyl groups0.0326003767808784



Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br>disease_data<br>


Uber Anatomy
Ontology termp-valuen
sympathetic nervous system5.30e-285
autonomic nervous system5.30e-285
epididymis1.65e-161
nucleus accumbens3.07e-161
ventral striatum3.07e-161
peripheral nervous system7.01e-168
neural tissue4.70e-092
middle temporal gyrus5.94e-092
neurectoderm3.52e-0886
ectoderm-derived structure7.63e-08171
ectoderm7.63e-08171
presumptive ectoderm7.63e-08171
Disease
Ontology termp-valuen
neuroectodermal tumor1.56e-7410
germ cell and embryonal cancer8.77e-3422
germ cell cancer8.77e-3422
neuroendocrine tumor1.83e-236
peripheral nerve sheath neoplasm4.70e-092
neurofibroma4.70e-092


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.