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|gostat_on_MCL_coexpression=GO:0048715;negative regulation of oligodendrocyte differentiation;0.0158608441727178;235402!GO:0048713;regulation of oligodendrocyte differentiation;0.0158608441727178;235402!GO:0014014;negative regulation of gliogenesis;0.0158608441727178;235402!GO:0045686;negative regulation of glial cell differentiation;0.0158608441727178;235402!GO:0005154;epidermal growth factor receptor binding;0.0158608441727178;235402!GO:0045685;regulation of glial cell differentiation;0.0158608441727178;235402!GO:0014013;regulation of gliogenesis;0.0158608441727178;235402!GO:0048709;oligodendrocyte differentiation;0.0158608441727178;235402!GO:0043491;protein kinase B signaling cascade;0.0158608441727178;235402!GO:0021954;central nervous system neuron development;0.0272368829429225;235402!GO:0021953;central nervous system neuron differentiation;0.0282934074455258;235402!GO:0010001;glial cell differentiation;0.040860385301581;235402!GO:0042063;gliogenesis;0.040860385301581;235402!
|gostat_on_MCL_coexpression=GO:0048715;negative regulation of oligodendrocyte differentiation;0.0158608441727178;235402!GO:0048713;regulation of oligodendrocyte differentiation;0.0158608441727178;235402!GO:0014014;negative regulation of gliogenesis;0.0158608441727178;235402!GO:0045686;negative regulation of glial cell differentiation;0.0158608441727178;235402!GO:0005154;epidermal growth factor receptor binding;0.0158608441727178;235402!GO:0045685;regulation of glial cell differentiation;0.0158608441727178;235402!GO:0014013;regulation of gliogenesis;0.0158608441727178;235402!GO:0048709;oligodendrocyte differentiation;0.0158608441727178;235402!GO:0043491;protein kinase B signaling cascade;0.0158608441727178;235402!GO:0021954;central nervous system neuron development;0.0272368829429225;235402!GO:0021953;central nervous system neuron differentiation;0.0282934074455258;235402!GO:0010001;glial cell differentiation;0.040860385301581;235402!GO:0042063;gliogenesis;0.040860385301581;235402!
|ontology_enrichment_celltype=
|ontology_enrichment_disease=
|ontology_enrichment_uberon=UBERON:0000955!8.33e-17!47;UBERON:0006238!8.33e-17!47;UBERON:0000073!4.45e-16!54;UBERON:0002616!5.89e-16!46;UBERON:0001049!3.58e-14!52;UBERON:0005068!3.58e-14!52;UBERON:0006241!3.58e-14!52;UBERON:0007135!3.58e-14!52;UBERON:0002021!9.36e-14!10;UBERON:0000411!9.36e-14!10;UBERON:0001950!9.36e-14!10;UBERON:0003080!1.32e-13!40;UBERON:0002780!9.94e-13!39;UBERON:0001890!9.94e-13!39;UBERON:0006240!9.94e-13!39;UBERON:0001017!4.77e-11!73;UBERON:0001016!1.76e-10!75;UBERON:0003528!5.87e-10!29;UBERON:0002791!5.87e-10!29;UBERON:0001893!5.87e-10!29;UBERON:0002619!6.91e-10!17;UBERON:0002346!8.80e-10!64;UBERON:0003075!8.80e-10!64;UBERON:0007284!8.80e-10!64;UBERON:0003056!1.12e-09!49;UBERON:0000956!7.57e-09!21;UBERON:0001869!7.57e-09!21;UBERON:0000203!7.57e-09!21;UBERON:0010371!3.94e-08!73;UBERON:0002020!1.04e-07!34;UBERON:0000025!1.93e-07!114;UBERON:0004121!9.04e-07!95;UBERON:0000924!9.04e-07!95;UBERON:0006601!9.04e-07!95
}}
}}

Revision as of 21:22, 11 October 2012


Phase1 CAGE Peaks

 Short description
Mm9::chr10:4978013..4978035,+p14@Syne1
Mm9::chr10:4978043..4978055,+p17@Syne1
Mm9::chr10:4978078..4978090,+p22@Syne1
Mm9::chr10:4978881..4978904,+p16@Syne1
Mm9::chr10:5007643..5007657,+p@chr10:5007643..5007657
+
Mm9::chr19:29038341..29038367,+p3@Ppapdc2
Mm9::chr9:56482905..56482942,-p2@Lingo1
Mm9::chrX:164857590..164857595,-p@chrX:164857590..164857595
-


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0048715negative regulation of oligodendrocyte differentiation0.0158608441727178
GO:0048713regulation of oligodendrocyte differentiation0.0158608441727178
GO:0014014negative regulation of gliogenesis0.0158608441727178
GO:0045686negative regulation of glial cell differentiation0.0158608441727178
GO:0005154epidermal growth factor receptor binding0.0158608441727178
GO:0045685regulation of glial cell differentiation0.0158608441727178
GO:0014013regulation of gliogenesis0.0158608441727178
GO:0048709oligodendrocyte differentiation0.0158608441727178
GO:0043491protein kinase B signaling cascade0.0158608441727178
GO:0021954central nervous system neuron development0.0272368829429225
GO:0021953central nervous system neuron differentiation0.0282934074455258
GO:0010001glial cell differentiation0.040860385301581
GO:0042063gliogenesis0.040860385301581



Relative expression of the co-expression cluster over median <br>Analyst:




Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>

Uber Anatomy
Ontology termp-valuen
brain8.33e-1747
future brain8.33e-1747
regional part of nervous system4.45e-1654
regional part of brain5.89e-1646
neural tube3.58e-1452
neural rod3.58e-1452
future spinal cord3.58e-1452
neural keel3.58e-1452
occipital lobe9.36e-1410
visual cortex9.36e-1410
neocortex9.36e-1410
anterior neural tube1.32e-1340
regional part of forebrain9.94e-1339
forebrain9.94e-1339
future forebrain9.94e-1339
central nervous system4.77e-1173
nervous system1.76e-1075
brain grey matter5.87e-1029
regional part of telencephalon5.87e-1029
telencephalon5.87e-1029
regional part of cerebral cortex6.91e-1017
neurectoderm8.80e-1064
neural plate8.80e-1064
presumptive neural plate8.80e-1064
pre-chordal neural plate1.12e-0949
cerebral cortex7.57e-0921
cerebral hemisphere7.57e-0921
pallium7.57e-0921
ecto-epithelium3.94e-0873
gray matter1.04e-0734
tube1.93e-07114
ectoderm-derived structure9.04e-0795
ectoderm9.04e-0795
presumptive ectoderm9.04e-0795


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs




JASPAR motifs


Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}

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