MCL coexpression mm9:592

Phase1 CAGE Peaks

	Short description
Mm9::chr10:23621952..23621962,+	p@chr10:23621952..23621962 +
Mm9::chr10:35205159..35205169,-	p@chr10:35205159..35205169 -
Mm9::chr16:48431394..48431436,+	p1@Morc1
Mm9::chr17:13102737..13102743,-	p3@Pnldc1
Mm9::chr18:36925872..36925891,-	p1@Dnd1
Mm9::chr2:25702816..25702827,-	p2@Sohlh1
Mm9::chr2:25702844..25702859,-	p1@Sohlh1
Mm9::chr7:6615049..6615056,-	p1@Zim2
Mm9::chr9:122656379..122656382,+	p3@Gm9524
Mm9::chrX:131499234..131499265,-	p1@Nxf2
Mm9::chrX:131499281..131499306,-	p2@Nxf2
Mm9::chrX:53466080..53466092,-	p1@Gm773

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0007276	gamete generation	0.00176087567671179
GO:0019953	sexual reproduction	0.00176087567671179
GO:0000003	reproduction	0.00346714036832184
GO:0016973	poly(A)+ mRNA export from nucleus	0.0164899966144239
GO:0007283	spermatogenesis	0.0164899966144239
GO:0048232	male gamete generation	0.0164899966144239
GO:0006406	mRNA export from nucleus	0.0382687687244097
GO:0006405	RNA export from nucleus	0.0397410998723541
GO:0001541	ovarian follicle development	0.0397410998723541
GO:0048477	oogenesis	0.0397410998723541
GO:0051168	nuclear export	0.0397410998723541
GO:0048869	cellular developmental process	0.0397410998723541
GO:0030154	cell differentiation	0.0397410998723541
GO:0007281	germ cell development	0.0397410998723541
GO:0022601	menstrual cycle phase	0.0397410998723541
GO:0003723	RNA binding	0.0397410998723541
GO:0022602	menstrual cycle process	0.0397410998723541
GO:0003729	mRNA binding	0.0397410998723541
GO:0008585	female gonad development	0.0397410998723541
GO:0007292	female gamete generation	0.0397410998723541
GO:0046545	development of primary female sexual characteristics	0.0397410998723541
GO:0046660	female sex differentiation	0.0397410998723541
GO:0042698	menstrual cycle	0.0412187783858621
GO:0051028	mRNA transport	0.0412187783858621
GO:0007275	multicellular organismal development	0.0412187783858621
GO:0050658	RNA transport	0.0412187783858621
GO:0051236	establishment of RNA localization	0.0412187783858621
GO:0050657	nucleic acid transport	0.0412187783858621
GO:0008406	gonad development	0.0412187783858621
GO:0006403	RNA localization	0.0412187783858621
GO:0048608	reproductive structure development	0.0414443362371201
GO:0015931	nucleobase, nucleoside, nucleotide and nucleic acid transport	0.0416551345554524
GO:0045137	development of primary sexual characteristics	0.0425821034744584
GO:0048609	reproductive process in a multicellular organism	0.049047802191363
GO:0032504	multicellular organism reproduction	0.049047802191363
GO:0007548	sex differentiation	0.049047802191363

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>

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Uber Anatomy

Ontology term	p-value	n
external genitalia	1.62e-52	17
indifferent external genitalia	1.62e-52	17
indifferent gonad	1.62e-52	17
gonad	1.52e-49	18
gonad primordium	1.52e-49	18
testis	7.48e-45	14
male reproductive organ	8.33e-42	15
male organism	3.86e-39	16
male reproductive system	3.86e-39	16
reproductive organ	6.77e-37	24
reproductive structure	5.65e-34	26
reproductive system	5.65e-34	26
body cavity	1.56e-23	37
body cavity or lining	1.56e-23	37
body cavity precursor	6.97e-23	38
anatomical cavity	2.89e-22	39
anatomical space	7.73e-15	57
immaterial anatomical entity	2.50e-10	79
female gonad	5.62e-09	3
mesoderm	1.55e-07	120
mesoderm-derived structure	1.55e-07	120
presumptive mesoderm	1.55e-07	120

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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