MCL coexpression mm9:1759

Phase1 CAGE Peaks

	Short description
Mm9::chr1:87791106..87791230,+	p1@Itm2c
Mm9::chr1:87799671..87799691,+	p@chr1:87799671..87799691 +
Mm9::chr1:87802991..87803007,+	p2@Itm2c
Mm9::chr1:87803583..87803596,+	p@chr1:87803583..87803596 +
Mm9::chr2:164328120..164328136,+	p@chr2:164328120..164328136 +

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

---

GO ID	GO name	FDR corrected p-value
GO:0016255	attachment of GPI anchor to protein	0.00986085235671182
GO:0042765	GPI-anchor transamidase complex	0.00986085235671182
GO:0003923	GPI-anchor transamidase activity	0.00986085235671182
GO:0030176	integral to endoplasmic reticulum membrane	0.0283344171572239
GO:0006506	GPI anchor biosynthetic process	0.0283344171572239
GO:0046489	phosphoinositide biosynthetic process	0.0283344171572239
GO:0006505	GPI anchor metabolic process	0.0283344171572239
GO:0031227	intrinsic to endoplasmic reticulum membrane	0.0283344171572239
GO:0046474	glycerophospholipid biosynthetic process	0.0317259818016279
GO:0051402	neuron apoptosis	0.0317259818016279
GO:0006497	protein amino acid lipidation	0.0317259818016279
GO:0030384	phosphoinositide metabolic process	0.0317259818016279
GO:0042158	lipoprotein biosynthetic process	0.0317259818016279
GO:0031301	integral to organelle membrane	0.0317259818016279
GO:0031300	intrinsic to organelle membrane	0.0317259818016279
GO:0042157	lipoprotein metabolic process	0.0317259818016279
GO:0006650	glycerophospholipid metabolic process	0.0317259818016279
GO:0008654	phospholipid biosynthetic process	0.0317259818016279
GO:0005789	endoplasmic reticulum membrane	0.0342124656357511
GO:0046467	membrane lipid biosynthetic process	0.0342124656357511
GO:0042175	nuclear envelope-endoplasmic reticulum network	0.0342124656357511
GO:0044432	endoplasmic reticulum part	0.035782004183405
GO:0006644	phospholipid metabolic process	0.049579035030091

Relative expression of the co-expression cluster over median <br>Analyst:

---

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

---

Cell Type

Ontology term	p-value	n

Uber Anatomy

Ontology term	p-value	n

Disease

Ontology term	p-value	n

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

---

Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
{{{tfbs_overrepresentation_jaspar}}}