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MCL coexpression mm9:351: Difference between revisions

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{{MCL_coexpression_mm9
{{MCL_coexpression_mm9
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|gostat_on_MCL_coexpression=GO:0042632;cholesterol homeostasis;0.00142028186206366;67470,14385!GO:0055088;lipid homeostasis;0.00142028186206366;67470,14385!GO:0055092;sterol homeostasis;0.00142028186206366;67470,14385!GO:0032642;regulation of chemokine production;0.0163918260012053;14385!GO:0032682;negative regulation of chemokine production;0.0163918260012053;14385!GO:0035166;post-embryonic hemopoiesis;0.018209647453125;14385!GO:0002318;myeloid progenitor cell differentiation;0.018209647453125;14385!GO:0045730;respiratory burst;0.018209647453125;14385!GO:0006089;lactate metabolic process;0.018209647453125;14385!GO:0015760;glucose-6-phosphate transport;0.0245783101549847;14385!GO:0001780;neutrophil homeostasis;0.0297861785229007;14385!GO:0002244;hemopoietic progenitor cell differentiation;0.0338786606807993;14385!GO:0019217;regulation of fatty acid metabolic process;0.0338786606807993;19013!GO:0048569;post-embryonic organ development;0.0338786606807993;14385!GO:0046983;protein dimerization activity;0.0338786606807993;233490,19013!GO:0048878;chemical homeostasis;0.0338786606807993;67470,14385!GO:0032602;chemokine production;0.0338786606807993;14385!GO:0002262;myeloid cell homeostasis;0.0338786606807993;14385!GO:0001818;negative regulation of cytokine production;0.0338786606807993;14385!GO:0032787;monocarboxylic acid metabolic process;0.0338786606807993;14385,19013!GO:0044262;cellular carbohydrate metabolic process;0.0419816813137615;14385,19013!GO:0015914;phospholipid transport;0.0419816813137615;67470!GO:0030593;neutrophil chemotaxis;0.0419816813137615;14385!GO:0016887;ATPase activity;0.0419816813137615;27409,67470!GO:0015918;sterol transport;0.0490436475972099;67470!
|gostat_on_MCL_coexpression=GO:0042632;cholesterol homeostasis;0.00142028186206366;67470,14385!GO:0055088;lipid homeostasis;0.00142028186206366;67470,14385!GO:0055092;sterol homeostasis;0.00142028186206366;67470,14385!GO:0032642;regulation of chemokine production;0.0163918260012053;14385!GO:0032682;negative regulation of chemokine production;0.0163918260012053;14385!GO:0035166;post-embryonic hemopoiesis;0.018209647453125;14385!GO:0002318;myeloid progenitor cell differentiation;0.018209647453125;14385!GO:0045730;respiratory burst;0.018209647453125;14385!GO:0006089;lactate metabolic process;0.018209647453125;14385!GO:0015760;glucose-6-phosphate transport;0.0245783101549847;14385!GO:0001780;neutrophil homeostasis;0.0297861785229007;14385!GO:0002244;hemopoietic progenitor cell differentiation;0.0338786606807993;14385!GO:0019217;regulation of fatty acid metabolic process;0.0338786606807993;19013!GO:0048569;post-embryonic organ development;0.0338786606807993;14385!GO:0046983;protein dimerization activity;0.0338786606807993;233490,19013!GO:0048878;chemical homeostasis;0.0338786606807993;67470,14385!GO:0032602;chemokine production;0.0338786606807993;14385!GO:0002262;myeloid cell homeostasis;0.0338786606807993;14385!GO:0001818;negative regulation of cytokine production;0.0338786606807993;14385!GO:0032787;monocarboxylic acid metabolic process;0.0338786606807993;14385,19013!GO:0044262;cellular carbohydrate metabolic process;0.0419816813137615;14385,19013!GO:0015914;phospholipid transport;0.0419816813137615;67470!GO:0030593;neutrophil chemotaxis;0.0419816813137615;14385!GO:0016887;ATPase activity;0.0419816813137615;27409,67470!GO:0015918;sterol transport;0.0490436475972099;67470!
}}
}}

Revision as of 12:40, 11 October 2012


Phase1 CAGE Peaks

 Short description
Mm9::chr11:102007554..102007574,-p1@ENSMUST00000123060
Mm9::chr11:53236625..53236637,-p1@Leap2
Mm9::chr11:98448507..98448567,-p1@Ormdl3
Mm9::chr13:96661836..96661857,-p2@Iqgap2
Mm9::chr14:56178830..56178841,+p4@Dcaf11
Mm9::chr15:85565338..85565355,+p7@Ppara
Mm9::chr15:85566051..85566080,+p4@Ppara
Mm9::chr16:21826090..21826118,+p@chr16:21826090..21826118
+
Mm9::chr17:85082272..85082284,-p2@Abcg5
Mm9::chr17:85082473..85082481,+p4@Abcg8
Mm9::chr17:85082530..85082533,+p8@Abcg8
Mm9::chr1:159456258..159456284,+p2@Sec16b
Mm9::chr2:27282009..27282055,-p3@Vav2
Mm9::chr2:27282056..27282083,-p2@Vav2
Mm9::chr3:104621398..104621422,-p3@Mov10
Mm9::chr3:40753703..40753736,+p@chr3:40753703..40753736
+
Mm9::chr3:40753740..40753774,+p@chr3:40753740..40753774
+
Mm9::chr4:149594810..149594830,-p@chr4:149594810..149594830
-
Mm9::chr5:89022703..89022738,+p@chr5:89022703..89022738
+
Mm9::chr7:97591412..97591431,+p2@Crebzf
Mm9::chr8:124900800..124900829,+p@chr8:124900800..124900829
+
Mm9::chr9:44205228..44205237,+p8@Slc37a4


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0042632cholesterol homeostasis0.00142028186206366
GO:0055088lipid homeostasis0.00142028186206366
GO:0055092sterol homeostasis0.00142028186206366
GO:0032642regulation of chemokine production0.0163918260012053
GO:0032682negative regulation of chemokine production0.0163918260012053
GO:0035166post-embryonic hemopoiesis0.018209647453125
GO:0002318myeloid progenitor cell differentiation0.018209647453125
GO:0045730respiratory burst0.018209647453125
GO:0006089lactate metabolic process0.018209647453125
GO:0015760glucose-6-phosphate transport0.0245783101549847
GO:0001780neutrophil homeostasis0.0297861785229007
GO:0002244hemopoietic progenitor cell differentiation0.0338786606807993
GO:0019217regulation of fatty acid metabolic process0.0338786606807993
GO:0048569post-embryonic organ development0.0338786606807993
GO:0046983protein dimerization activity0.0338786606807993
GO:0048878chemical homeostasis0.0338786606807993
GO:0032602chemokine production0.0338786606807993
GO:0002262myeloid cell homeostasis0.0338786606807993
GO:0001818negative regulation of cytokine production0.0338786606807993
GO:0032787monocarboxylic acid metabolic process0.0338786606807993
GO:0044262cellular carbohydrate metabolic process0.0419816813137615
GO:0015914phospholipid transport0.0419816813137615
GO:0030593neutrophil chemotaxis0.0419816813137615
GO:0016887ATPase activity0.0419816813137615
GO:0015918sterol transport0.0490436475972099



Relative expression of the co-expression cluster over median <br>Analyst:





Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>


Cell Type
Ontology termp-valuen

Uber Anatomy
Ontology termp-valuen

Disease
Ontology termp-valuen


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)

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