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MCL coexpression mm9:331: Difference between revisions

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{{MCL_coexpression_mm9
{{MCL_coexpression_mm9
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|coexpression_dpi_cluster_scores_median=0,0,0,0,0,1.14756711822292,0.934074900710798,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.724169566317542,0.646914200749391,0.197068726315728,0.360268799800303,0.397770886202509,0,0,0.248609075768884,0,0,0,0.554859279314428,0.366224770954178,0.400136370136393,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0570741246689917,0,0,0,0,0,0,0,0,0,0,0.0469568706916304,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.380504223622236,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.758295219768782,0.143140628990209,0,0,0,0,0,0,0.168653336497203,0,0,0,0.0773548534010084,0.278483662180697,0.294390989111819,0.387986490278782,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.199470399831828,0,0,0,0,0,0,0,0,0,0,0.291073584836546,0,0,0,0,0,0,0.0504648943632345,0.182845846232878,0.100105043383282,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0403878614760544,0.0581625411619175,0.0480053095083702,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0
|gostat_on_MCL_coexpression=GO:0004715;non-membrane spanning protein tyrosine kinase activity;8.11094323245837e-05;17179,15162,12169!GO:0007242;intracellular signaling cascade;0.00196897682908386;17179,15162,12169,326623,71130!GO:0004713;protein-tyrosine kinase activity;0.00196897682908386;17179,15162,12169!GO:0007165;signal transduction;0.00713790286926552;246709,17179,15162,233080,12169,326623,71130!GO:0007154;cell communication;0.00854678678617675;246709,17179,15162,233080,12169,326623,71130!GO:0016299;regulator of G-protein signaling activity;0.0192255013928163;246709!GO:0004672;protein kinase activity;0.032023213734179;17179,15162,12169!GO:0007250;activation of NF-kappaB-inducing kinase;0.032023213734179;326623!GO:0006468;protein amino acid phosphorylation;0.032023213734179;17179,15162,12169!GO:0016773;phosphotransferase activity, alcohol group as acceptor;0.033607780848479;17179,15162,12169!GO:0016310;phosphorylation;0.033607780848479;17179,15162,12169!GO:0045744;negative regulation of G-protein coupled receptor protein signaling pathway;0.033607780848479;246709!GO:0006793;phosphorus metabolic process;0.0452943172759087;17179,15162,12169!GO:0006796;phosphate metabolic process;0.0452943172759087;17179,15162,12169!
|gostat_on_MCL_coexpression=GO:0004715;non-membrane spanning protein tyrosine kinase activity;8.11094323245837e-05;17179,15162,12169!GO:0007242;intracellular signaling cascade;0.00196897682908386;17179,15162,12169,326623,71130!GO:0004713;protein-tyrosine kinase activity;0.00196897682908386;17179,15162,12169!GO:0007165;signal transduction;0.00713790286926552;246709,17179,15162,233080,12169,326623,71130!GO:0007154;cell communication;0.00854678678617675;246709,17179,15162,233080,12169,326623,71130!GO:0016299;regulator of G-protein signaling activity;0.0192255013928163;246709!GO:0004672;protein kinase activity;0.032023213734179;17179,15162,12169!GO:0007250;activation of NF-kappaB-inducing kinase;0.032023213734179;326623!GO:0006468;protein amino acid phosphorylation;0.032023213734179;17179,15162,12169!GO:0016773;phosphotransferase activity, alcohol group as acceptor;0.033607780848479;17179,15162,12169!GO:0016310;phosphorylation;0.033607780848479;17179,15162,12169!GO:0045744;negative regulation of G-protein coupled receptor protein signaling pathway;0.033607780848479;246709!GO:0006793;phosphorus metabolic process;0.0452943172759087;17179,15162,12169!GO:0006796;phosphate metabolic process;0.0452943172759087;17179,15162,12169!
}}
}}

Revision as of 12:40, 11 October 2012


Phase1 CAGE Peaks

 Short description
Mm9::chr10:80720893..80720912,+p4@Matk
Mm9::chr11:3431562..3431575,-p@chr11:3431562..3431575
-
Mm9::chr11:95885854..95885872,+p1@Gip
Mm9::chr17:35218137..35218148,-p@chr17:35218137..35218148
-
Mm9::chr17:37030973..37030980,-p@chr17:37030973..37030980
-
Mm9::chr19:40905054..40905084,+p@chr19:40905054..40905084
+
Mm9::chr1:146024315..146024326,-p2@Rgs13
Mm9::chr1:146024389..146024411,-p1@Rgs13
Mm9::chr1:153099939..153099982,-p@chr1:153099939..153099982
-
Mm9::chr2:152933392..152933409,+p@chr2:152933392..152933409
+
Mm9::chr2:152933438..152933445,+p@chr2:152933438..152933445
+
Mm9::chr3:144759807..144759821,+p@chr3:144759807..144759821
+
Mm9::chr4:63406089..63406095,-p1@Tnfsf15
Mm9::chr6:145093993..145094003,+p6@Lrmp
Mm9::chr6:72471665..72471668,-p6@Sh2d6
Mm9::chr6:72471687..72471701,-p1@Sh2d6
Mm9::chr6:72471704..72471733,-p2@Sh2d6
Mm9::chr7:150279910..150279946,-p@chr7:150279910..150279946
-
Mm9::chr7:31641206..31641219,-p1@Ffar3
Mm9::chr7:53358071..53358073,+p@chr7:53358071..53358073
+
Mm9::chr8:120027901..120027907,+p@chr8:120027901..120027907
+
Mm9::chr9:51137003..51137028,-p1@1810046K07Rik
Mm9::chr9:54381927..54381934,+p1@Sh2d7
Mm9::chrX:160688308..160688314,-p3@Bmx


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0004715non-membrane spanning protein tyrosine kinase activity8.11094323245837e-05
GO:0007242intracellular signaling cascade0.00196897682908386
GO:0004713protein-tyrosine kinase activity0.00196897682908386
GO:0007165signal transduction0.00713790286926552
GO:0007154cell communication0.00854678678617675
GO:0016299regulator of G-protein signaling activity0.0192255013928163
GO:0004672protein kinase activity0.032023213734179
GO:0007250activation of NF-kappaB-inducing kinase0.032023213734179
GO:0006468protein amino acid phosphorylation0.032023213734179
GO:0016773phosphotransferase activity, alcohol group as acceptor0.033607780848479
GO:0016310phosphorylation0.033607780848479
GO:0045744negative regulation of G-protein coupled receptor protein signaling pathway0.033607780848479
GO:0006793phosphorus metabolic process0.0452943172759087
GO:0006796phosphate metabolic process0.0452943172759087



Relative expression of the co-expression cluster over median <br>Analyst:





Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>


Cell Type
Ontology termp-valuen

Uber Anatomy
Ontology termp-valuen

Disease
Ontology termp-valuen


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)

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