MCL coexpression mm9:1968

Phase1 CAGE Peaks

	Short description
Mm9::chr11:49059026..49059041,+	p9@Mgat1
Mm9::chr12:85379313..85379329,+	p2@Acot4
Mm9::chr18:61878972..61878986,-	p@chr18:61878972..61878986 -
Mm9::chr7:134985979..134986002,-	p@chr7:134985979..134986002 -

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0004144	diacylglycerol O-acyltransferase activity	0.00562138780611094
GO:0006104	succinyl-CoA metabolic process	0.00562138780611094
GO:0046459	short-chain fatty acid metabolic process	0.00562138780611094
GO:0006651	diacylglycerol biosynthetic process	0.00562138780611094
GO:0003846	2-acylglycerol O-acyltransferase activity	0.00562138780611094
GO:0046460	neutral lipid biosynthetic process	0.00562138780611094
GO:0046463	acylglycerol biosynthetic process	0.00562138780611094
GO:0044255	cellular lipid metabolic process	0.00562138780611094
GO:0046339	diacylglycerol metabolic process	0.00562138780611094
GO:0046504	glycerol ether biosynthetic process	0.00562138780611094
GO:0045017	glycerolipid biosynthetic process	0.00562138780611094
GO:0043648	dicarboxylic acid metabolic process	0.00562138780611094
GO:0006629	lipid metabolic process	0.00562138780611094
GO:0016290	palmitoyl-CoA hydrolase activity	0.00603086878670909
GO:0006637	acyl-CoA metabolic process	0.00603086878670909
GO:0016291	acyl-CoA thioesterase activity	0.00603086878670909
GO:0016411	acylglycerol O-acyltransferase activity	0.00603086878670909
GO:0006100	tricarboxylic acid cycle intermediate metabolic process	0.00657174040685285
GO:0016289	CoA hydrolase activity	0.00664073462887965
GO:0006071	glycerol metabolic process	0.00749096282138268
GO:0019751	polyol metabolic process	0.0075095313391231
GO:0006639	acylglycerol metabolic process	0.00819905965580648
GO:0046486	glycerolipid metabolic process	0.00819905965580648
GO:0006638	neutral lipid metabolic process	0.00819905965580648
GO:0006662	glycerol ether metabolic process	0.00819905965580648
GO:0008374	O-acyltransferase activity	0.00909559239437412
GO:0045454	cell redox homeostasis	0.0122581718694476
GO:0042579	microbody	0.0230862485008273
GO:0005777	peroxisome	0.0230862485008273
GO:0016790	thiolester hydrolase activity	0.0230862485008273
GO:0006732	coenzyme metabolic process	0.0392737580302111
GO:0006631	fatty acid metabolic process	0.0392737580302111
GO:0008415	acyltransferase activity	0.0394928238126641
GO:0016747	transferase activity, transferring groups other than amino-acyl groups	0.0394928238126641
GO:0016746	transferase activity, transferring acyl groups	0.039927238538215
GO:0051186	cofactor metabolic process	0.0407707605133528
GO:0019725	cellular homeostasis	0.0439637461505754
GO:0032787	monocarboxylic acid metabolic process	0.0439637461505754
GO:0008610	lipid biosynthetic process	0.0474319260194453
GO:0044262	cellular carbohydrate metabolic process	0.0481029168663236
GO:0006066	alcohol metabolic process	0.0481029168663236
GO:0044444	cytoplasmic part	0.0481029168663236

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

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Cell Type

Ontology term	p-value	n

Uber Anatomy

Ontology term	p-value	n

Disease

Ontology term	p-value	n

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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