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MCL coexpression mm9:1936: Difference between revisions

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{{MCL_coexpression_mm9|gostat_on_MCL_coexpression=GO:0016494;C-X-C chemokine receptor activity;0.00547855147099107;59289!GO:0019958;C-X-C chemokine binding;0.00547855147099107;59289!GO:0016493;C-C chemokine receptor activity;0.00547855147099107;59289!GO:0019957;C-C chemokine binding;0.00547855147099107;59289!GO:0001637;G-protein chemoattractant receptor activity;0.00547855147099107;59289!GO:0004950;chemokine receptor activity;0.00547855147099107;59289!GO:0019956;chemokine binding;0.00547855147099107;59289!GO:0019955;cytokine binding;0.0128472031994741;59289!GO:0001653;peptide receptor activity;0.0156467430011505;59289!GO:0008528;peptide receptor activity, G-protein coupled;0.0156467430011505;59289!GO:0042277;peptide binding;0.0181290248676432;59289!}}
{{MCL_coexpression_mm9
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|gostat_on_MCL_coexpression=GO:0016494;C-X-C chemokine receptor activity;0.00547855147099107;59289!GO:0019958;C-X-C chemokine binding;0.00547855147099107;59289!GO:0016493;C-C chemokine receptor activity;0.00547855147099107;59289!GO:0019957;C-C chemokine binding;0.00547855147099107;59289!GO:0001637;G-protein chemoattractant receptor activity;0.00547855147099107;59289!GO:0004950;chemokine receptor activity;0.00547855147099107;59289!GO:0019956;chemokine binding;0.00547855147099107;59289!GO:0019955;cytokine binding;0.0128472031994741;59289!GO:0001653;peptide receptor activity;0.0156467430011505;59289!GO:0008528;peptide receptor activity, G-protein coupled;0.0156467430011505;59289!GO:0042277;peptide binding;0.0181290248676432;59289!
}}

Revision as of 11:30, 11 October 2012


Phase1 CAGE Peaks

 Short description
Mm9::chr11:101036754..101036758,-p1@Ccr10
Mm9::chr12:114498239..114498250,-p@chr12:114498239..114498250
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Mm9::chr12:114498257..114498273,-p@chr12:114498257..114498273
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Mm9::chr12:114864234..114864248,-p1@ENSMUST00000103446


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0016494C-X-C chemokine receptor activity0.00547855147099107
GO:0019958C-X-C chemokine binding0.00547855147099107
GO:0016493C-C chemokine receptor activity0.00547855147099107
GO:0019957C-C chemokine binding0.00547855147099107
GO:0001637G-protein chemoattractant receptor activity0.00547855147099107
GO:0004950chemokine receptor activity0.00547855147099107
GO:0019956chemokine binding0.00547855147099107
GO:0019955cytokine binding0.0128472031994741
GO:0001653peptide receptor activity0.0156467430011505
GO:0008528peptide receptor activity, G-protein coupled0.0156467430011505
GO:0042277peptide binding0.0181290248676432



Relative expression of the co-expression cluster over median <br>Analyst:


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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

Cell Type
Ontology termp-valuen

Uber Anatomy
Ontology termp-valuen

Disease
Ontology termp-valuen


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs




JASPAR motifs


Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}

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