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MCL coexpression mm9:600: Difference between revisions

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{{MCL_coexpression_mm9|gostat_on_MCL_coexpression=GO:0045736;negative regulation of cyclin-dependent protein kinase activity;6.23135703143626e-06;12575,12578!GO:0004861;cyclin-dependent protein kinase inhibitor activity;1.45398330733513e-05;12575,12578!GO:0000079;regulation of cyclin-dependent protein kinase activity;1.90402575960552e-05;12575,12578!GO:0004860;protein kinase inhibitor activity;3.9984540951716e-05;12575,12578!GO:0030888;regulation of B cell proliferation;3.9984540951716e-05;12575,12578!GO:0019210;kinase inhibitor activity;3.9984540951716e-05;12575,12578!GO:0042100;B cell proliferation;5.20763409055744e-05;12575,12578!GO:0006469;negative regulation of protein kinase activity;6.63733938348437e-05;12575,12578!GO:0033673;negative regulation of kinase activity;6.63733938348437e-05;12575,12578!GO:0050864;regulation of B cell activation;6.63733938348437e-05;12575,12578!GO:0051348;negative regulation of transferase activity;6.63733938348437e-05;12575,12578!GO:0007050;cell cycle arrest;8.56811591822485e-05;12575,12578!GO:0043086;negative regulation of catalytic activity;8.63602173202896e-05;12575,12578!GO:0050670;regulation of lymphocyte proliferation;9.5408999881324e-05;12575,12578!GO:0032944;regulation of mononuclear cell proliferation;9.5408999881324e-05;12575,12578!GO:0019887;protein kinase regulator activity;0.000126769169608281;12575,12578!GO:0032943;mononuclear cell proliferation;0.000147639432823766;12575,12578!GO:0019207;kinase regulator activity;0.000147639432823766;12575,12578!GO:0046651;lymphocyte proliferation;0.000147639432823766;12575,12578!GO:0051249;regulation of lymphocyte activation;0.000172542499620451;12575,12578!GO:0042113;B cell activation;0.000172542499620451;12575,12578!GO:0050865;regulation of cell activation;0.000172542499620451;12575,12578!GO:0045786;negative regulation of progression through cell cycle;0.000298715677694475;12575,12578!GO:0008285;negative regulation of cell proliferation;0.000298715677694475;12575,12578!GO:0045859;regulation of protein kinase activity;0.00033238058405681;12575,12578!GO:0043549;regulation of kinase activity;0.000345360980088448;12575,12578!GO:0051338;regulation of transferase activity;0.000347917434255191;12575,12578!GO:0000074;regulation of progression through cell cycle;0.000584300995929853;12575,12578!GO:0046649;lymphocyte activation;0.00059236837780091;12575,12578!GO:0043071;positive regulation of non-apoptotic programmed cell death;0.00059236837780091;12575!GO:0016244;non-apoptotic programmed cell death;0.00059236837780091;12575!GO:0043070;regulation of non-apoptotic programmed cell death;0.00059236837780091;12575!GO:0045321;leukocyte activation;0.000644975998621454;12575,12578!GO:0004857;enzyme inhibitor activity;0.000644975998621454;12575,12578!GO:0001775;cell activation;0.000721353759210549;12575,12578!GO:0050790;regulation of catalytic activity;0.000997645726835604;12575,12578!GO:0033087;negative regulation of immature T cell proliferation;0.000997645726835604;12578!GO:0033088;negative regulation of immature T cell proliferation in the thymus;0.000997645726835604;12578!GO:0051239;regulation of multicellular organismal process;0.0010253245289803;12575,12578!GO:0065009;regulation of a molecular function;0.001243545187586;12575,12578!GO:0042127;regulation of cell proliferation;0.00126871442388828;12575,12578!GO:0030332;cyclin binding;0.00135391068072313;12575!GO:0051726;regulation of cell cycle;0.00147511678563941;12575,12578!GO:0033080;immature T cell proliferation in the thymus;0.001613125978755;12578!GO:0033079;immature T cell proliferation;0.001613125978755;12578!GO:0033083;regulation of immature T cell proliferation;0.001613125978755;12578!GO:0033084;regulation of immature T cell proliferation in the thymus;0.001613125978755;12578!GO:0008283;cell proliferation;0.00230410917234263;12575,12578!GO:0048103;somatic stem cell division;0.00232079898255502;12578!GO:0000307;cyclin-dependent protein kinase holoenzyme complex;0.00265337413755587;12575!GO:0030889;negative regulation of B cell proliferation;0.00297288676570365;12578!GO:0022402;cell cycle process;0.00303730721766891;12575,12578!GO:0017145;stem cell division;0.00321820197480138;12578!GO:0006915;apoptosis;0.00347919357513534;12575,12578!GO:0012501;programmed cell death;0.00353046029921064;12575,12578!GO:0050869;negative regulation of B cell activation;0.00363859322660616;12578!GO:0008219;cell death;0.00363859322660616;12575,12578!GO:0016265;death;0.00363859322660616;12575,12578!GO:0007569;cell aging;0.00410573729206283;12578!GO:0030890;positive regulation of B cell proliferation;0.00410573729206283;12575!GO:0007049;cell cycle;0.00412965310414495;12575,12578!GO:0002376;immune system process;0.00431174729559889;12575,12578!GO:0048523;negative regulation of cellular process;0.00550853610086116;12575,12578!GO:0050672;negative regulation of lymphocyte proliferation;0.00553819046196241;12578!GO:0032945;negative regulation of mononuclear cell proliferation;0.00553819046196241;12578!GO:0016301;kinase activity;0.00562450782962479;12575,12578!GO:0048519;negative regulation of biological process;0.00598149821554142;12575,12578!GO:0009411;response to UV;0.00676547334841651;12575!GO:0033077;T cell differentiation in the thymus;0.00676547334841651;12578!GO:0051250;negative regulation of lymphocyte activation;0.00676547334841651;12578!GO:0016772;transferase activity, transferring phosphorus-containing groups;0.00684045775682157;12575,12578!GO:0050871;positive regulation of B cell activation;0.00684045775682157;12575!GO:0007568;aging;0.00726533549337855;12578!GO:0048468;cell development;0.00859156771462019;12575,12578!GO:0032946;positive regulation of mononuclear cell proliferation;0.00897044840445193;12575!GO:0050671;positive regulation of lymphocyte proliferation;0.00897044840445193;12575!GO:0042129;regulation of T cell proliferation;0.0103279077926027;12578!GO:0016072;rRNA metabolic process;0.0126990586550902;12578!GO:0006364;rRNA processing;0.0126990586550902;12578!GO:0042098;T cell proliferation;0.013012826050804;12578!GO:0051251;positive regulation of lymphocyte activation;0.014078079385034;12575!GO:0030217;T cell differentiation;0.014078079385034;12578!GO:0050863;regulation of T cell activation;0.0143636908787096;12578!GO:0009416;response to light stimulus;0.0164409904305137;12575!GO:0048869;cellular developmental process;0.0169711008751167;12575,12578!GO:0030154;cell differentiation;0.0169711008751167;12575,12578!GO:0016740;transferase activity;0.0177298342497547;12575,12578!GO:0030098;lymphocyte differentiation;0.0197578127502482;12578!GO:0009314;response to radiation;0.0197578127502482;12575!GO:0008544;epidermis development;0.0201668869473389;12578!GO:0007398;ectoderm development;0.0209812073796822;12578!GO:0005730;nucleolus;0.0219823875503924;12578!GO:0042110;T cell activation;0.0239743421323824;12578!GO:0042254;ribosome biogenesis and assembly;0.0249212517907133;12578!GO:0002521;leukocyte differentiation;0.0252534270819102;12578!GO:0043066;negative regulation of apoptosis;0.0293016798776038;12575!GO:0043069;negative regulation of programmed cell death;0.0293872403622387;12575!GO:0043068;positive regulation of programmed cell death;0.031771972700846;12575!GO:0009628;response to abiotic stimulus;0.0320202372355373;12575!GO:0008284;positive regulation of cell proliferation;0.0332022488739404;12575!GO:0022613;ribonucleoprotein complex biogenesis and assembly;0.0352890386214833;12578!GO:0030097;hemopoiesis;0.038435743270726;12578!GO:0032502;developmental process;0.0396246347091916;12575,12578!GO:0006974;response to DNA damage stimulus;0.0415787003990648;12575!GO:0048534;hemopoietic or lymphoid organ development;0.0415787003990648;12578!GO:0051301;cell division;0.0415787003990648;12578!GO:0002520;immune system development;0.0435798320167287;12578!GO:0009719;response to endogenous stimulus;0.0435798320167287;12575!GO:0050794;regulation of cellular process;0.046956514775283;12575,12578!GO:0009888;tissue development;0.048051995656815;12578!}}
{{MCL_coexpression_mm9
|coexpression_dpi_cluster_scores_mean=-0.0340769738076358,-0.0178866900176871,-0.0119883852945622,-0.039945288714244,-0.0495091052751821,-0.0157684268538527,-0.0139048761596431,-0.0495091052751821,-0.0447420036843848,-0.0495091052751821,-0.0495091052751821,-0.0495091052751821,-0.0437898274100862,-0.0410800023283993,-0.0286981205093568,-0.0115529075269781,-0.0303143568482738,-0.0354874619650084,-0.0495091052751821,-0.0495091052751821,0.046750852760748,0.136204184066776,0.129011666263079,0.0393314409033491,0.0458821306271693,-0.00052234681619775,0.00502447132149767,-0.000867067995692333,-0.043212812915399,-0.0495091052751821,0.0179936533954424,0.154138703258272,0.137474720732862,0.0766991522581089,-0.0403255284691286,-0.0495091052751821,-0.0293372125069707,-0.0368558532555369,-0.0495091052751821,-0.0495091052751821,-0.0495091052751821,-0.0118264630899133,-0.0495091052751821,1.18371326746404,1.17904675674118,1.15764274852389,0.900425763929893,0.300031812032066,0.47515571709645,0.547014298404373,0.472259224195005,0.448544344022596,-0.0438956050906864,-0.0297690832340494,-0.0495091052751821,0.398320274757804,0.290467385019869,0.661306506711253,-0.0238757361683636,-0.0341420283440996,-0.0495091052751821,0.904434020123647,0.714662805023258,0.651418198129469,0.713029715414017,0.623821613015433,0.749162457519151,0.733005594277654,-0.0308218638947536,-0.0362752789346345,-0.0240945932688989,0.056525130580051,0.0419360107631841,-0.0369634078043488,-0.0264424991837259,-0.0495091052751821,0.0451374938496502,0.0134691479696978,0.0145287441731235,-0.0275859950463687,-0.00698317401210465,-0.0495091052751821,0.0555168148453519,0.00931728802288883,0.0222833377239713,0.0402395912998132,0.052485881468798,-0.0256700394261767,0.172522244928043,0.187579906544866,0.0596301681246152,-0.0270414465517676,-0.0307339493436001,-0.0495091052751821,-0.031390347663827,-0.0495091052751821,0.082846032418262,0.28411958194847,0.210319753193283,0.207393220970978,-0.0153735514529405,0.190947764976522,0.0421558988578215,-0.0495091052751821,0.252011084762254,0.258055467051194,0.220519723110664,-0.00153904317654044,0.0863300230861932,0.114112280283364,0.0278439734804751,0.0611197624643467,0.0739820042752433,0.0224620862011353,0.0917781683744033,0.0633913114331435,0.132267727623859,0.16530540660271,0.0332243005141884,0.0822994921807187,0.0319203200316744,0.0714589894226959,-0.0114290619219682,-0.0328271788043804,0.0339728009664256,0.0139967749943844,-0.0495091052751821,-0.0325013069641117,-0.0451798571485879,0.00824749368603785,0.00527219504724983,0.016271531517666,-0.0343204187304576,0.00348617015665966,0.00500086620099963,0.01272504523492,0.0751266630683921,0.0843159291019371,0.0259777573614933,0.0368995399025925,0.0329148522555913,-0.0305248363797024,0.0284587176429397,-0.00432049252404514,0.0528578760169341,0.0487533499751703,0.0110129974260979,0.0583971286791512,-0.00188928044546324,-0.00375827671648874,-0.00546141020025437,0.0323937199790058,0.0696262679052613,0.0322083359514367,0.0883951512120725,0.0348007034894431,-0.0495091052751821,-0.0495091052751821,-0.0495091052751821,0.0799247874914408,0.051082546403328,0.0653445303986364,0.0846170733881766,0.069235148269351,0.0585928145013965,0.070826788303315,0.0958156111450472,0.0495900745295462,0.0281699140607339,0.144220857188948,0.0732609885502551,0.0474744734422382,0.0450940470484765,0.0638865307501141,-0.0136032439794954,0.0401806861408047,-0.0495091052751821,-0.0495091052751821,-0.000331244667853951,-0.0192777287989508,0.0200801696213074,0.0201793359714939,0.00480217021192716,0.00824015899332403,0.0106470088445529,0.0112645902783566,0.0375675357898815,0.0291984471634642,0.0261816541693772,0.0805514192175313,0.025416644672964,0.00559568649402129,0.0305388570232263,-0.00924642312529926,0.00512144213224044,0.00168800268962947,0.0100615568673975,0.0485909619142199,0.0139332568522579,0.0278188038384359,0.0101104956805422,0.00992196158668325,-0.0170865318033445,-0.0292374860657539,-0.0430145956150955,-0.0161689431181557,-0.0213225055374211,-0.0171220100161055,0.0130476497341789,-0.0147578138151567,0.0337953670105597,-0.0119228137549849,-0.000483062340307913,0.0284841494508956,0.00735684430472442,-0.0250578342793728,-0.00689296841510286,-0.0108161265089691,0.0527083575920759,-0.0253189820945327,-0.0248937192473591,-0.0177742224403191,-0.0355812493537866,-0.017385012963816,0.00193244414763402,0.0505658911092316,0.0706963687132415,0.0898491816394677,0.0499256681202704,0.0660459698431434,0.119911152512162,0.0948187523762678,0.136049172682995,0.095409731065905,0.0225546646217825,0.0549469506702038,0.0298231596810095,0.0388441153813597,0.217733679854293,0.124265158189497,0.410904310801136,0.341319654197517,0.315965864586781,0.456510760489604,0.508840756818262,0.464420297949805,0.490921780649813,0.527774012800027,0.443410643025593,-0.00951336686607083,0.104203392090207,0.0454773908500761,0.0675053882070424,0.123980548022307,0.0171588926097092,0.0393371065391433,0.0229685224669982,0.0835106993564539,0.043523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|gostat_on_MCL_coexpression=GO:0045736;negative regulation of cyclin-dependent protein kinase activity;6.23135703143626e-06;12575,12578!GO:0004861;cyclin-dependent protein kinase inhibitor activity;1.45398330733513e-05;12575,12578!GO:0000079;regulation of cyclin-dependent protein kinase activity;1.90402575960552e-05;12575,12578!GO:0004860;protein kinase inhibitor activity;3.9984540951716e-05;12575,12578!GO:0030888;regulation of B cell proliferation;3.9984540951716e-05;12575,12578!GO:0019210;kinase inhibitor activity;3.9984540951716e-05;12575,12578!GO:0042100;B cell proliferation;5.20763409055744e-05;12575,12578!GO:0006469;negative regulation of protein kinase activity;6.63733938348437e-05;12575,12578!GO:0033673;negative regulation of kinase activity;6.63733938348437e-05;12575,12578!GO:0050864;regulation of B cell activation;6.63733938348437e-05;12575,12578!GO:0051348;negative regulation of transferase activity;6.63733938348437e-05;12575,12578!GO:0007050;cell cycle arrest;8.56811591822485e-05;12575,12578!GO:0043086;negative regulation of catalytic activity;8.63602173202896e-05;12575,12578!GO:0050670;regulation of lymphocyte proliferation;9.5408999881324e-05;12575,12578!GO:0032944;regulation of mononuclear cell proliferation;9.5408999881324e-05;12575,12578!GO:0019887;protein kinase regulator activity;0.000126769169608281;12575,12578!GO:0032943;mononuclear cell proliferation;0.000147639432823766;12575,12578!GO:0019207;kinase regulator activity;0.000147639432823766;12575,12578!GO:0046651;lymphocyte proliferation;0.000147639432823766;12575,12578!GO:0051249;regulation of lymphocyte activation;0.000172542499620451;12575,12578!GO:0042113;B cell activation;0.000172542499620451;12575,12578!GO:0050865;regulation of cell activation;0.000172542499620451;12575,12578!GO:0045786;negative regulation of progression through cell cycle;0.000298715677694475;12575,12578!GO:0008285;negative regulation of cell proliferation;0.000298715677694475;12575,12578!GO:0045859;regulation of protein kinase activity;0.00033238058405681;12575,12578!GO:0043549;regulation of kinase activity;0.000345360980088448;12575,12578!GO:0051338;regulation of transferase activity;0.000347917434255191;12575,12578!GO:0000074;regulation of progression through cell cycle;0.000584300995929853;12575,12578!GO:0046649;lymphocyte activation;0.00059236837780091;12575,12578!GO:0043071;positive regulation of non-apoptotic programmed cell death;0.00059236837780091;12575!GO:0016244;non-apoptotic programmed cell death;0.00059236837780091;12575!GO:0043070;regulation of non-apoptotic programmed cell death;0.00059236837780091;12575!GO:0045321;leukocyte activation;0.000644975998621454;12575,12578!GO:0004857;enzyme inhibitor activity;0.000644975998621454;12575,12578!GO:0001775;cell activation;0.000721353759210549;12575,12578!GO:0050790;regulation of catalytic activity;0.000997645726835604;12575,12578!GO:0033087;negative regulation of immature T cell proliferation;0.000997645726835604;12578!GO:0033088;negative regulation of immature T cell proliferation in the thymus;0.000997645726835604;12578!GO:0051239;regulation of multicellular organismal process;0.0010253245289803;12575,12578!GO:0065009;regulation of a molecular function;0.001243545187586;12575,12578!GO:0042127;regulation of cell proliferation;0.00126871442388828;12575,12578!GO:0030332;cyclin binding;0.00135391068072313;12575!GO:0051726;regulation of cell cycle;0.00147511678563941;12575,12578!GO:0033080;immature T cell proliferation in the thymus;0.001613125978755;12578!GO:0033079;immature T cell proliferation;0.001613125978755;12578!GO:0033083;regulation of immature T cell proliferation;0.001613125978755;12578!GO:0033084;regulation of immature T cell proliferation in the thymus;0.001613125978755;12578!GO:0008283;cell proliferation;0.00230410917234263;12575,12578!GO:0048103;somatic stem cell division;0.00232079898255502;12578!GO:0000307;cyclin-dependent protein kinase holoenzyme complex;0.00265337413755587;12575!GO:0030889;negative regulation of B cell proliferation;0.00297288676570365;12578!GO:0022402;cell cycle process;0.00303730721766891;12575,12578!GO:0017145;stem cell division;0.00321820197480138;12578!GO:0006915;apoptosis;0.00347919357513534;12575,12578!GO:0012501;programmed cell death;0.00353046029921064;12575,12578!GO:0050869;negative regulation of B cell activation;0.00363859322660616;12578!GO:0008219;cell death;0.00363859322660616;12575,12578!GO:0016265;death;0.00363859322660616;12575,12578!GO:0007569;cell aging;0.00410573729206283;12578!GO:0030890;positive regulation of B cell proliferation;0.00410573729206283;12575!GO:0007049;cell cycle;0.00412965310414495;12575,12578!GO:0002376;immune system process;0.00431174729559889;12575,12578!GO:0048523;negative regulation of cellular process;0.00550853610086116;12575,12578!GO:0050672;negative regulation of lymphocyte proliferation;0.00553819046196241;12578!GO:0032945;negative regulation of mononuclear cell proliferation;0.00553819046196241;12578!GO:0016301;kinase activity;0.00562450782962479;12575,12578!GO:0048519;negative regulation of biological process;0.00598149821554142;12575,12578!GO:0009411;response to UV;0.00676547334841651;12575!GO:0033077;T cell differentiation in the thymus;0.00676547334841651;12578!GO:0051250;negative regulation of lymphocyte activation;0.00676547334841651;12578!GO:0016772;transferase activity, transferring phosphorus-containing groups;0.00684045775682157;12575,12578!GO:0050871;positive regulation of B cell activation;0.00684045775682157;12575!GO:0007568;aging;0.00726533549337855;12578!GO:0048468;cell development;0.00859156771462019;12575,12578!GO:0032946;positive regulation of mononuclear cell proliferation;0.00897044840445193;12575!GO:0050671;positive regulation of lymphocyte proliferation;0.00897044840445193;12575!GO:0042129;regulation of T cell proliferation;0.0103279077926027;12578!GO:0016072;rRNA metabolic process;0.0126990586550902;12578!GO:0006364;rRNA processing;0.0126990586550902;12578!GO:0042098;T cell proliferation;0.013012826050804;12578!GO:0051251;positive regulation of lymphocyte activation;0.014078079385034;12575!GO:0030217;T cell differentiation;0.014078079385034;12578!GO:0050863;regulation of T cell activation;0.0143636908787096;12578!GO:0009416;response to light stimulus;0.0164409904305137;12575!GO:0048869;cellular developmental process;0.0169711008751167;12575,12578!GO:0030154;cell differentiation;0.0169711008751167;12575,12578!GO:0016740;transferase activity;0.0177298342497547;12575,12578!GO:0030098;lymphocyte differentiation;0.0197578127502482;12578!GO:0009314;response to radiation;0.0197578127502482;12575!GO:0008544;epidermis development;0.0201668869473389;12578!GO:0007398;ectoderm development;0.0209812073796822;12578!GO:0005730;nucleolus;0.0219823875503924;12578!GO:0042110;T cell activation;0.0239743421323824;12578!GO:0042254;ribosome biogenesis and assembly;0.0249212517907133;12578!GO:0002521;leukocyte differentiation;0.0252534270819102;12578!GO:0043066;negative regulation of apoptosis;0.0293016798776038;12575!GO:0043069;negative regulation of programmed cell death;0.0293872403622387;12575!GO:0043068;positive regulation of programmed cell death;0.031771972700846;12575!GO:0009628;response to abiotic stimulus;0.0320202372355373;12575!GO:0008284;positive regulation of cell proliferation;0.0332022488739404;12575!GO:0022613;ribonucleoprotein complex biogenesis and assembly;0.0352890386214833;12578!GO:0030097;hemopoiesis;0.038435743270726;12578!GO:0032502;developmental process;0.0396246347091916;12575,12578!GO:0006974;response to DNA damage stimulus;0.0415787003990648;12575!GO:0048534;hemopoietic or lymphoid organ development;0.0415787003990648;12578!GO:0051301;cell division;0.0415787003990648;12578!GO:0002520;immune system development;0.0435798320167287;12578!GO:0009719;response to endogenous stimulus;0.0435798320167287;12575!GO:0050794;regulation of cellular process;0.046956514775283;12575,12578!GO:0009888;tissue development;0.048051995656815;12578!
}}

Revision as of 11:11, 11 October 2012


Phase1 CAGE Peaks

 Short description
Mm9::chr11:118165162..118165220,-p@chr11:118165162..118165220
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Mm9::chr11:5763981..5764006,+p@chr11:5763981..5764006
+
Mm9::chr11:5770554..5770565,+p@chr11:5770554..5770565
+
Mm9::chr11:5771774..5771785,+p@chr11:5771774..5771785
+
Mm9::chr17:29227914..29227965,+p2@Cdkn1a
Mm9::chr1:137662795..137662802,+p3@Phlda3
Mm9::chr1:137662818..137662834,+p2@Phlda3
Mm9::chr4:88920480..88920487,-p@chr4:88920480..88920487
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Mm9::chr4:88928017..88928055,-p2@Cdkn2a
Mm9::chr4:88928056..88928065,-p4@Cdkn2a
Mm9::chr7:74764902..74764914,-p@chr7:74764902..74764914
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Mm9::chr9:58095257..58095272,-p@chr9:58095257..58095272
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Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0045736negative regulation of cyclin-dependent protein kinase activity6.23135703143626e-06
GO:0004861cyclin-dependent protein kinase inhibitor activity1.45398330733513e-05
GO:0000079regulation of cyclin-dependent protein kinase activity1.90402575960552e-05
GO:0004860protein kinase inhibitor activity3.9984540951716e-05
GO:0030888regulation of B cell proliferation3.9984540951716e-05
GO:0019210kinase inhibitor activity3.9984540951716e-05
GO:0042100B cell proliferation5.20763409055744e-05
GO:0006469negative regulation of protein kinase activity6.63733938348437e-05
GO:0033673negative regulation of kinase activity6.63733938348437e-05
GO:0050864regulation of B cell activation6.63733938348437e-05
GO:0051348negative regulation of transferase activity6.63733938348437e-05
GO:0007050cell cycle arrest8.56811591822485e-05
GO:0043086negative regulation of catalytic activity8.63602173202896e-05
GO:0050670regulation of lymphocyte proliferation9.5408999881324e-05
GO:0032944regulation of mononuclear cell proliferation9.5408999881324e-05
GO:0019887protein kinase regulator activity0.000126769169608281
GO:0032943mononuclear cell proliferation0.000147639432823766
GO:0019207kinase regulator activity0.000147639432823766
GO:0046651lymphocyte proliferation0.000147639432823766
GO:0051249regulation of lymphocyte activation0.000172542499620451
GO:0042113B cell activation0.000172542499620451
GO:0050865regulation of cell activation0.000172542499620451
GO:0045786negative regulation of progression through cell cycle0.000298715677694475
GO:0008285negative regulation of cell proliferation0.000298715677694475
GO:0045859regulation of protein kinase activity0.00033238058405681
GO:0043549regulation of kinase activity0.000345360980088448
GO:0051338regulation of transferase activity0.000347917434255191
GO:0000074regulation of progression through cell cycle0.000584300995929853
GO:0046649lymphocyte activation0.00059236837780091
GO:0043071positive regulation of non-apoptotic programmed cell death0.00059236837780091
GO:0016244non-apoptotic programmed cell death0.00059236837780091
GO:0043070regulation of non-apoptotic programmed cell death0.00059236837780091
GO:0045321leukocyte activation0.000644975998621454
GO:0004857enzyme inhibitor activity0.000644975998621454
GO:0001775cell activation0.000721353759210549
GO:0050790regulation of catalytic activity0.000997645726835604
GO:0033087negative regulation of immature T cell proliferation0.000997645726835604
GO:0033088negative regulation of immature T cell proliferation in the thymus0.000997645726835604
GO:0051239regulation of multicellular organismal process0.0010253245289803
GO:0065009regulation of a molecular function0.001243545187586
GO:0042127regulation of cell proliferation0.00126871442388828
GO:0030332cyclin binding0.00135391068072313
GO:0051726regulation of cell cycle0.00147511678563941
GO:0033080immature T cell proliferation in the thymus0.001613125978755
GO:0033079immature T cell proliferation0.001613125978755
GO:0033083regulation of immature T cell proliferation0.001613125978755
GO:0033084regulation of immature T cell proliferation in the thymus0.001613125978755
GO:0008283cell proliferation0.00230410917234263
GO:0048103somatic stem cell division0.00232079898255502
GO:0000307cyclin-dependent protein kinase holoenzyme complex0.00265337413755587
GO:0030889negative regulation of B cell proliferation0.00297288676570365
GO:0022402cell cycle process0.00303730721766891
GO:0017145stem cell division0.00321820197480138
GO:0006915apoptosis0.00347919357513534
GO:0012501programmed cell death0.00353046029921064
GO:0050869negative regulation of B cell activation0.00363859322660616
GO:0008219cell death0.00363859322660616
GO:0016265death0.00363859322660616
GO:0007569cell aging0.00410573729206283
GO:0030890positive regulation of B cell proliferation0.00410573729206283
GO:0007049cell cycle0.00412965310414495
GO:0002376immune system process0.00431174729559889
GO:0048523negative regulation of cellular process0.00550853610086116
GO:0050672negative regulation of lymphocyte proliferation0.00553819046196241
GO:0032945negative regulation of mononuclear cell proliferation0.00553819046196241
GO:0016301kinase activity0.00562450782962479
GO:0048519negative regulation of biological process0.00598149821554142
GO:0009411response to UV0.00676547334841651
GO:0033077T cell differentiation in the thymus0.00676547334841651
GO:0051250negative regulation of lymphocyte activation0.00676547334841651
GO:0016772transferase activity, transferring phosphorus-containing groups0.00684045775682157
GO:0050871positive regulation of B cell activation0.00684045775682157
GO:0007568aging0.00726533549337855
GO:0048468cell development0.00859156771462019
GO:0032946positive regulation of mononuclear cell proliferation0.00897044840445193
GO:0050671positive regulation of lymphocyte proliferation0.00897044840445193
GO:0042129regulation of T cell proliferation0.0103279077926027
GO:0016072rRNA metabolic process0.0126990586550902
GO:0006364rRNA processing0.0126990586550902
GO:0042098T cell proliferation0.013012826050804
GO:0051251positive regulation of lymphocyte activation0.014078079385034
GO:0030217T cell differentiation0.014078079385034
GO:0050863regulation of T cell activation0.0143636908787096
GO:0009416response to light stimulus0.0164409904305137
GO:0048869cellular developmental process0.0169711008751167
GO:0030154cell differentiation0.0169711008751167
GO:0016740transferase activity0.0177298342497547
GO:0030098lymphocyte differentiation0.0197578127502482
GO:0009314response to radiation0.0197578127502482
GO:0008544epidermis development0.0201668869473389
GO:0007398ectoderm development0.0209812073796822
GO:0005730nucleolus0.0219823875503924
GO:0042110T cell activation0.0239743421323824
GO:0042254ribosome biogenesis and assembly0.0249212517907133
GO:0002521leukocyte differentiation0.0252534270819102
GO:0043066negative regulation of apoptosis0.0293016798776038
GO:0043069negative regulation of programmed cell death0.0293872403622387
GO:0043068positive regulation of programmed cell death0.031771972700846
GO:0009628response to abiotic stimulus0.0320202372355373
GO:0008284positive regulation of cell proliferation0.0332022488739404
GO:0022613ribonucleoprotein complex biogenesis and assembly0.0352890386214833
GO:0030097hemopoiesis0.038435743270726
GO:0032502developmental process0.0396246347091916
GO:0006974response to DNA damage stimulus0.0415787003990648
GO:0048534hemopoietic or lymphoid organ development0.0415787003990648
GO:0051301cell division0.0415787003990648
GO:0002520immune system development0.0435798320167287
GO:0009719response to endogenous stimulus0.0435798320167287
GO:0050794regulation of cellular process0.046956514775283
GO:0009888tissue development0.048051995656815



Relative expression of the co-expression cluster over median <br>Analyst:


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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

Cell Type
Ontology termp-valuen

Uber Anatomy
Ontology termp-valuen

Disease
Ontology termp-valuen


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs




JASPAR motifs


Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}

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