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{{MCL_coexpression_mm9|gostat_on_MCL_coexpression=GO:0005739;mitochondrion;6.27523475493706e-07;104776,58875,17850,110821,66885,13171,78038,71147,66904!GO:0016421;CoA carboxylase activity;6.99466227946502e-07;110821,78038,66904!GO:0016885;ligase activity, forming carbon-carbon bonds;8.15675020897826e-07;110821,78038,66904!GO:0004658;propionyl-CoA carboxylase activity;2.66318474284288e-05;110821,66904!GO:0044444;cytoplasmic part;0.000348096818503853;104776,58875,67993,17850,110821,66885,13171,78038,66904,71147!GO:0019752;carboxylic acid metabolic process;0.000401318676234845;110821,66885,58875,66904,71147!GO:0006082;organic acid metabolic process;0.000401318676234845;110821,66885,58875,66904,71147!GO:0032787;monocarboxylic acid metabolic process;0.000401318676234845;110821,66885,66904,71147!GO:0050662;coenzyme binding;0.00187420164834863;66885,13171,58875!GO:0006631;fatty acid metabolic process;0.00437035419185468;66885,66904,71147!GO:0048037;cofactor binding;0.00458679476633284;66885,13171,58875!GO:0006767;water-soluble vitamin metabolic process;0.00647224500148516;110821,58875!GO:0043754;dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity;0.00712211691228839;13171!GO:0050093;methanol dehydrogenase activity;0.00712211691228839;76187!GO:0008442;3-hydroxyisobutyrate dehydrogenase activity;0.00712211691228839;58875!GO:0006768;biotin metabolic process;0.00712211691228839;110821!GO:0004494;methylmalonyl-CoA mutase activity;0.00712211691228839;17850!GO:0016937;short-branched-chain-acyl-CoA dehydrogenase activity;0.00712211691228839;66885!GO:0004491;methylmalonate-semialdehyde dehydrogenase (acylating) activity;0.00712211691228839;104776!GO:0006573;valine metabolic process;0.00712211691228839;58875!GO:0000210;NAD+ diphosphatase activity;0.00712211691228839;67993!GO:0006766;vitamin metabolic process;0.00891888207802721;110821,58875!GO:0006633;fatty acid biosynthetic process;0.00996741276421327;66904,71147!GO:0005737;cytoplasm;0.00996741276421327;104776,58875,67993,17850,110821,66885,13171,78038,66904,71147!GO:0046394;carboxylic acid biosynthetic process;0.00996741276421327;66904,71147!GO:0016053;organic acid biosynthetic process;0.00996741276421327;66904,71147!GO:0009343;biotin carboxylase complex;0.00996741276421327;66904!GO:0004485;methylcrotonoyl-CoA carboxylase activity;0.00996741276421327;78038!GO:0009317;acetyl-CoA carboxylase complex;0.00996741276421327;66904!GO:0004315;3-oxoacyl-[acyl-carrier-protein] synthase activity;0.00996741276421327;71147!GO:0016874;ligase activity;0.0108751984293086;110821,78038,66904!GO:0016491;oxidoreductase activity;0.0128106815241885;104776,76187,66885,58875!GO:0004075;biotin carboxylase activity;0.0128106815241885;66904!GO:0004616;phosphogluconate dehydrogenase (decarboxylating) activity;0.0128106815241885;58875!GO:0003989;acetyl-CoA carboxylase activity;0.0128106815241885;66904!GO:0019842;vitamin binding;0.0154437815892189;110821,17850!GO:0009374;biotin binding;0.0160294455529876;110821!GO:0016616;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;0.0160294455529876;76187,58875!GO:0016614;oxidoreductase activity, acting on CH-OH group of donors;0.0173664581883205;76187,58875!GO:0031406;carboxylic acid binding;0.0173664581883205;13171!GO:0031419;cobalamin binding;0.0173664581883205;17850!GO:0004312;fatty-acid synthase activity;0.0173664581883205;71147!GO:0031405;lipoic acid binding;0.0173664581883205;13171!GO:0009081;branched chain family amino acid metabolic process;0.0232159235755607;58875!GO:0004551;nucleotide diphosphatase activity;0.0232159235755607;67993!GO:0006098;pentose-phosphate shunt;0.0249314317801191;58875!GO:0006740;NADPH regeneration;0.0249314317801191;58875!GO:0044255;cellular lipid metabolic process;0.0249314317801191;66885,66904,71147!GO:0008415;acyltransferase activity;0.0286860817617896;13171,71147!GO:0016747;transferase activity, transferring groups other than amino-acyl groups;0.0287585165101509;13171,71147!GO:0043231;intracellular membrane-bound organelle;0.028983523454345;104776,58875,67993,17850,110821,66885,13171,78038,66904,71147!GO:0043227;membrane-bound organelle;0.028983523454345;104776,58875,67993,17850,110821,66885,13171,78038,66904,71147!GO:0016746;transferase activity, transferring acyl groups;0.0293142905754877;13171,71147!GO:0050897;cobalt ion binding;0.0303585470970815;17850!GO:0051186;cofactor metabolic process;0.0310630974510198;110821,58875!GO:0006629;lipid metabolic process;0.0314364698181849;66885,66904,71147!GO:0006739;NADP metabolic process;0.0365655058362674;58875!GO:0003995;acyl-CoA dehydrogenase activity;0.041039433488073;66885!GO:0008610;lipid biosynthetic process;0.045193925620091;66904,71147!}}
{{MCL_coexpression_mm9
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|gostat_on_MCL_coexpression=GO:0005739;mitochondrion;6.27523475493706e-07;104776,58875,17850,110821,66885,13171,78038,71147,66904!GO:0016421;CoA carboxylase activity;6.99466227946502e-07;110821,78038,66904!GO:0016885;ligase activity, forming carbon-carbon bonds;8.15675020897826e-07;110821,78038,66904!GO:0004658;propionyl-CoA carboxylase activity;2.66318474284288e-05;110821,66904!GO:0044444;cytoplasmic part;0.000348096818503853;104776,58875,67993,17850,110821,66885,13171,78038,66904,71147!GO:0019752;carboxylic acid metabolic process;0.000401318676234845;110821,66885,58875,66904,71147!GO:0006082;organic acid metabolic process;0.000401318676234845;110821,66885,58875,66904,71147!GO:0032787;monocarboxylic acid metabolic process;0.000401318676234845;110821,66885,66904,71147!GO:0050662;coenzyme binding;0.00187420164834863;66885,13171,58875!GO:0006631;fatty acid metabolic process;0.00437035419185468;66885,66904,71147!GO:0048037;cofactor binding;0.00458679476633284;66885,13171,58875!GO:0006767;water-soluble vitamin metabolic process;0.00647224500148516;110821,58875!GO:0043754;dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity;0.00712211691228839;13171!GO:0050093;methanol dehydrogenase activity;0.00712211691228839;76187!GO:0008442;3-hydroxyisobutyrate dehydrogenase activity;0.00712211691228839;58875!GO:0006768;biotin metabolic process;0.00712211691228839;110821!GO:0004494;methylmalonyl-CoA mutase activity;0.00712211691228839;17850!GO:0016937;short-branched-chain-acyl-CoA dehydrogenase activity;0.00712211691228839;66885!GO:0004491;methylmalonate-semialdehyde dehydrogenase (acylating) activity;0.00712211691228839;104776!GO:0006573;valine metabolic process;0.00712211691228839;58875!GO:0000210;NAD+ diphosphatase activity;0.00712211691228839;67993!GO:0006766;vitamin metabolic process;0.00891888207802721;110821,58875!GO:0006633;fatty acid biosynthetic process;0.00996741276421327;66904,71147!GO:0005737;cytoplasm;0.00996741276421327;104776,58875,67993,17850,110821,66885,13171,78038,66904,71147!GO:0046394;carboxylic acid biosynthetic process;0.00996741276421327;66904,71147!GO:0016053;organic acid biosynthetic process;0.00996741276421327;66904,71147!GO:0009343;biotin carboxylase complex;0.00996741276421327;66904!GO:0004485;methylcrotonoyl-CoA carboxylase activity;0.00996741276421327;78038!GO:0009317;acetyl-CoA carboxylase complex;0.00996741276421327;66904!GO:0004315;3-oxoacyl-[acyl-carrier-protein] synthase activity;0.00996741276421327;71147!GO:0016874;ligase activity;0.0108751984293086;110821,78038,66904!GO:0016491;oxidoreductase activity;0.0128106815241885;104776,76187,66885,58875!GO:0004075;biotin carboxylase activity;0.0128106815241885;66904!GO:0004616;phosphogluconate dehydrogenase (decarboxylating) activity;0.0128106815241885;58875!GO:0003989;acetyl-CoA carboxylase activity;0.0128106815241885;66904!GO:0019842;vitamin binding;0.0154437815892189;110821,17850!GO:0009374;biotin binding;0.0160294455529876;110821!GO:0016616;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;0.0160294455529876;76187,58875!GO:0016614;oxidoreductase activity, acting on CH-OH group of donors;0.0173664581883205;76187,58875!GO:0031406;carboxylic acid binding;0.0173664581883205;13171!GO:0031419;cobalamin binding;0.0173664581883205;17850!GO:0004312;fatty-acid synthase activity;0.0173664581883205;71147!GO:0031405;lipoic acid binding;0.0173664581883205;13171!GO:0009081;branched chain family amino acid metabolic process;0.0232159235755607;58875!GO:0004551;nucleotide diphosphatase activity;0.0232159235755607;67993!GO:0006098;pentose-phosphate shunt;0.0249314317801191;58875!GO:0006740;NADPH regeneration;0.0249314317801191;58875!GO:0044255;cellular lipid metabolic process;0.0249314317801191;66885,66904,71147!GO:0008415;acyltransferase activity;0.0286860817617896;13171,71147!GO:0016747;transferase activity, transferring groups other than amino-acyl groups;0.0287585165101509;13171,71147!GO:0043231;intracellular membrane-bound organelle;0.028983523454345;104776,58875,67993,17850,110821,66885,13171,78038,66904,71147!GO:0043227;membrane-bound organelle;0.028983523454345;104776,58875,67993,17850,110821,66885,13171,78038,66904,71147!GO:0016746;transferase activity, transferring acyl groups;0.0293142905754877;13171,71147!GO:0050897;cobalt ion binding;0.0303585470970815;17850!GO:0051186;cofactor metabolic process;0.0310630974510198;110821,58875!GO:0006629;lipid metabolic process;0.0314364698181849;66885,66904,71147!GO:0006739;NADP metabolic process;0.0365655058362674;58875!GO:0003995;acyl-CoA dehydrogenase activity;0.041039433488073;66885!GO:0008610;lipid biosynthetic process;0.045193925620091;66904,71147!
}}

Revision as of 11:10, 11 October 2012


Phase1 CAGE Peaks

 Short description
Mm9::chr10:29032970..29033027,+p2@Echdc1
Mm9::chr12:85791894..85791968,-p1@Aldh6a1
Mm9::chr13:100785517..100785602,-p1@Mccc2
Mm9::chr14:122933527..122933589,+p1@Pcca
Mm9::chr14:17075823..17075858,-p1@Oxsm
Mm9::chr17:41071625..41071700,+p1@Mut
Mm9::chr17:59152687..59152766,-p1@Nudt12
Mm9::chr1:9538130..9538182,+p1@Adhfe1
Mm9::chr2:103325295..103325315,-p2@Cat
Mm9::chr3:116216012..116216062,+p1@Dbt
Mm9::chr6:13019879..13019895,+p2@Tmem106b
Mm9::chr6:52590297..52590380,-p1@Hibadh
Mm9::chr7:138554147..138554240,+p1@Acadsb
Mm9::chr9:100935276..100935286,-p1@Pccb


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0005739mitochondrion6.27523475493706e-07
GO:0016421CoA carboxylase activity6.99466227946502e-07
GO:0016885ligase activity, forming carbon-carbon bonds8.15675020897826e-07
GO:0004658propionyl-CoA carboxylase activity2.66318474284288e-05
GO:0044444cytoplasmic part0.000348096818503853
GO:0019752carboxylic acid metabolic process0.000401318676234845
GO:0006082organic acid metabolic process0.000401318676234845
GO:0032787monocarboxylic acid metabolic process0.000401318676234845
GO:0050662coenzyme binding0.00187420164834863
GO:0006631fatty acid metabolic process0.00437035419185468
GO:0048037cofactor binding0.00458679476633284
GO:0006767water-soluble vitamin metabolic process0.00647224500148516
GO:0043754dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity0.00712211691228839
GO:0050093methanol dehydrogenase activity0.00712211691228839
GO:00084423-hydroxyisobutyrate dehydrogenase activity0.00712211691228839
GO:0006768biotin metabolic process0.00712211691228839
GO:0004494methylmalonyl-CoA mutase activity0.00712211691228839
GO:0016937short-branched-chain-acyl-CoA dehydrogenase activity0.00712211691228839
GO:0004491methylmalonate-semialdehyde dehydrogenase (acylating) activity0.00712211691228839
GO:0006573valine metabolic process0.00712211691228839
GO:0000210NAD+ diphosphatase activity0.00712211691228839
GO:0006766vitamin metabolic process0.00891888207802721
GO:0006633fatty acid biosynthetic process0.00996741276421327
GO:0005737cytoplasm0.00996741276421327
GO:0046394carboxylic acid biosynthetic process0.00996741276421327
GO:0016053organic acid biosynthetic process0.00996741276421327
GO:0009343biotin carboxylase complex0.00996741276421327
GO:0004485methylcrotonoyl-CoA carboxylase activity0.00996741276421327
GO:0009317acetyl-CoA carboxylase complex0.00996741276421327
GO:00043153-oxoacyl-[acyl-carrier-protein] synthase activity0.00996741276421327
GO:0016874ligase activity0.0108751984293086
GO:0016491oxidoreductase activity0.0128106815241885
GO:0004075biotin carboxylase activity0.0128106815241885
GO:0004616phosphogluconate dehydrogenase (decarboxylating) activity0.0128106815241885
GO:0003989acetyl-CoA carboxylase activity0.0128106815241885
GO:0019842vitamin binding0.0154437815892189
GO:0009374biotin binding0.0160294455529876
GO:0016616oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor0.0160294455529876
GO:0016614oxidoreductase activity, acting on CH-OH group of donors0.0173664581883205
GO:0031406carboxylic acid binding0.0173664581883205
GO:0031419cobalamin binding0.0173664581883205
GO:0004312fatty-acid synthase activity0.0173664581883205
GO:0031405lipoic acid binding0.0173664581883205
GO:0009081branched chain family amino acid metabolic process0.0232159235755607
GO:0004551nucleotide diphosphatase activity0.0232159235755607
GO:0006098pentose-phosphate shunt0.0249314317801191
GO:0006740NADPH regeneration0.0249314317801191
GO:0044255cellular lipid metabolic process0.0249314317801191
GO:0008415acyltransferase activity0.0286860817617896
GO:0016747transferase activity, transferring groups other than amino-acyl groups0.0287585165101509
GO:0043231intracellular membrane-bound organelle0.028983523454345
GO:0043227membrane-bound organelle0.028983523454345
GO:0016746transferase activity, transferring acyl groups0.0293142905754877
GO:0050897cobalt ion binding0.0303585470970815
GO:0051186cofactor metabolic process0.0310630974510198
GO:0006629lipid metabolic process0.0314364698181849
GO:0006739NADP metabolic process0.0365655058362674
GO:0003995acyl-CoA dehydrogenase activity0.041039433488073
GO:0008610lipid biosynthetic process0.045193925620091



Relative expression of the co-expression cluster over median <br>Analyst:


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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

Cell Type
Ontology termp-valuen

Uber Anatomy
Ontology termp-valuen

Disease
Ontology termp-valuen


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs




JASPAR motifs


Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}

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