Coexpression cluster:C101

Full id: C101_small_cerebellum_maxillary_colon_parietal_epididymis_merkel

Phase1 CAGE Peaks

Hg19::chr11:1671395..1671423,-	p@chr11:1671395..1671423 -
Hg19::chr11:2291849..2291858,-	p4@ASCL2
Hg19::chr11:2292201..2292212,-	p3@ASCL2
Hg19::chr11:2292226..2292270,-	p1@ASCL2
Hg19::chr11:32635079..32635088,-	p@chr11:32635079..32635088 -
Hg19::chr11:32635094..32635099,-	p@chr11:32635094..32635099 -
Hg19::chr11:32635116..32635125,-	p@chr11:32635116..32635125 -
Hg19::chr11:32635130..32635137,-	p@chr11:32635130..32635137 -
Hg19::chr11:32635146..32635151,-	p@chr11:32635146..32635151 -
Hg19::chr11:33826559..33826594,+	p@chr11:33826559..33826594 +
Hg19::chr11:61976154..61976157,+	p2@SCGB2A1
Hg19::chr11:62009653..62009664,+	p4@SCGB1D2
Hg19::chr11:62009732..62009752,+	p3@SCGB1D2
Hg19::chr11:62009756..62009783,+	p1@SCGB1D2
Hg19::chr11:90181744..90181756,+	p@chr11:90181744..90181756 +
Hg19::chr11:95746788..95746792,+	p@chr11:95746788..95746792 +
Hg19::chr12:2693428..2693469,+	p@chr12:2693428..2693469 +
Hg19::chr12:31272124..31272129,-	p3@uc001rjy.2
Hg19::chr13:24232177..24232184,-	p@chr13:24232177..24232184 -
Hg19::chr13:24289097..24289102,-	p@chr13:24289097..24289102 -
Hg19::chr13:39261206..39261220,+	p1@FREM2
Hg19::chr13:39332751..39332761,+	p@chr13:39332751..39332761 +
Hg19::chr15:23810119..23810126,+	p3@MKRN3
Hg19::chr15:23827035..23827038,+	p@chr15:23827035..23827038 +
Hg19::chr15:32270259..32270270,+	p@chr15:32270259..32270270 +
Hg19::chr15:67649588..67649598,+	p8@IQCH
Hg19::chr16:50420325..50420329,+	p@chr16:50420325..50420329 +
Hg19::chr16:50583403..50583421,+	p@chr16:50583403..50583421 +
Hg19::chr16:50586808..50586853,+	p@chr16:50586808..50586853 +
Hg19::chr16:50594555..50594558,+	p@chr16:50594555..50594558 +
Hg19::chr16:50609021..50609023,+	p@chr16:50609021..50609023 +
Hg19::chr16:50655573..50655586,-	p@chr16:50655573..50655586 -
Hg19::chr16:50659419..50659431,+	p@chr16:50659419..50659431 +
Hg19::chr16:50664175..50664188,+	p@chr16:50664175..50664188 +
Hg19::chr16:50664743..50664753,+	p@chr16:50664743..50664753 +
Hg19::chr16:50666194..50666212,+	p@chr16:50666194..50666212 +
Hg19::chr16:50666256..50666270,+	p@chr16:50666256..50666270 +
Hg19::chr16:50667519..50667529,+	p@chr16:50667519..50667529 +
Hg19::chr16:50667622..50667641,+	p@chr16:50667622..50667641 +
Hg19::chr16:50667686..50667701,-	p@chr16:50667686..50667701 -
Hg19::chr16:50680042..50680056,+	p@chr16:50680042..50680056 +
Hg19::chr17:37764898..37764905,-	p@chr17:37764898..37764905 -
Hg19::chr17:47946107..47946118,+	p@chr17:47946107..47946118 +
Hg19::chr18:10456027..10456060,-	p@chr18:10456027..10456060 -
Hg19::chr18:10456176..10456181,-	p@chr18:10456176..10456181 -
Hg19::chr18:10456186..10456191,-	p@chr18:10456186..10456191 -
Hg19::chr18:10456221..10456228,-	p@chr18:10456221..10456228 -
Hg19::chr18:10525925..10525936,+	p7@NAPG
Hg19::chr18:3459683..3459693,+	p@chr18:3459683..3459693 +
Hg19::chr18:35250402..35250410,+	p@chr18:35250402..35250410 +
Hg19::chr18:36955178..36955187,-	p@chr18:36955178..36955187 -
Hg19::chr18:52989415..52989429,-	p63@TCF4
Hg19::chr18:53165290..53165321,-	p@chr18:53165290..53165321 -
Hg19::chr18:72611750..72611755,+	p@chr18:72611750..72611755 +
Hg19::chr18:72611763..72611770,+	p@chr18:72611763..72611770 +
Hg19::chr19:13974949..13974960,+	p@chr19:13974949..13974960 +
Hg19::chr19:18060992..18060999,+	p@chr19:18060992..18060999 +
Hg19::chr19:18061245..18061251,+	p@chr19:18061245..18061251 +
Hg19::chr19:18061742..18061752,-	p@chr19:18061742..18061752 -
Hg19::chr19:30433219..30433233,+	p3@URI1
Hg19::chr19:30495196..30495205,+	p@chr19:30495196..30495205 +
Hg19::chr19:30495593..30495598,+	p@chr19:30495593..30495598 +
Hg19::chr19:42637515..42637525,+	p@chr19:42637515..42637525 +
Hg19::chr19:50832943..50832951,+	p9@NR1H2
Hg19::chr19:54385244..54385256,-	p@chr19:54385244..54385256 -
Hg19::chr1:156828879..156828914,-	p1@INSRR
Hg19::chr1:156830458..156830475,-	p@chr1:156830458..156830475 -
Hg19::chr1:183486836..183486856,+	p@chr1:183486836..183486856 +
Hg19::chr1:183486863..183486872,+	p@chr1:183486863..183486872 +
Hg19::chr1:183486877..183486880,+	p@chr1:183486877..183486880 +
Hg19::chr1:216798763..216798766,-	p@chr1:216798763..216798766 -
Hg19::chr1:216799658..216799665,-	p@chr1:216799658..216799665 -
Hg19::chr1:230889639..230889650,+	p@chr1:230889639..230889650 +
Hg19::chr1:81910488..81910495,+	p@chr1:81910488..81910495 +
Hg19::chr20:2397889..2397925,+	p@chr20:2397889..2397925 +
Hg19::chr20:33539679..33539680,-	p7@GSS
Hg19::chr20:33539681..33539688,-	p5@GSS
Hg19::chr20:44664535..44664572,-	p@chr20:44664535..44664572 -
Hg19::chr20:57562489..57562529,+	p10@TH1L
Hg19::chr20:5903677..5903685,+	p@chr20:5903677..5903685 +
Hg19::chr20:5903794..5903803,-	p@chr20:5903794..5903803 -
Hg19::chr2:130067563..130067579,-	p@chr2:130067563..130067579 -
Hg19::chr2:130067584..130067595,-	p@chr2:130067584..130067595 -
Hg19::chr2:130067633..130067649,-	p@chr2:130067633..130067649 -
Hg19::chr2:130067654..130067664,-	p@chr2:130067654..130067664 -
Hg19::chr2:130076372..130076376,-	p@chr2:130076372..130076376 -
Hg19::chr2:165698803..165698810,-	p22@COBLL1
Hg19::chr2:166522142..166522151,+	p@chr2:166522142..166522151 +
Hg19::chr2:172967017..172967029,-	p8@DLX2
Hg19::chr2:172967225..172967232,-	p7@DLX2
Hg19::chr2:172967242..172967265,-	p2@DLX2
Hg19::chr2:172967266..172967271,-	p6@DLX2
Hg19::chr2:172967276..172967296,-	p3@DLX2
Hg19::chr2:172967323..172967336,-	p4@DLX2
Hg19::chr2:172967353..172967365,-	p5@DLX2
Hg19::chr2:175198519..175198542,-	p@chr2:175198519..175198542 -
Hg19::chr2:183381027..183381046,-	p@chr2:183381027..183381046 -
Hg19::chr2:183381629..183381645,-	p@chr2:183381629..183381645 -
Hg19::chr2:200298219..200298241,-	p@chr2:200298219..200298241 -
Hg19::chr2:37126075..37126076,-	p@chr2:37126075..37126076 -
Hg19::chr2:51259507..51259525,-	p22@NRXN1
Hg19::chr2:51259528..51259554,-	p10@NRXN1
Hg19::chr3:65583115..65583144,-	p@chr3:65583115..65583144 -
Hg19::chr3:80727046..80727051,-	p@chr3:80727046..80727051 -
Hg19::chr4:107157608..107157617,-	p@chr4:107157608..107157617 -
Hg19::chr4:107158685..107158699,-	p@chr4:107158685..107158699 -
Hg19::chr5:2334898..2334930,-	p@chr5:2334898..2334930 -
Hg19::chr5:33986219..33986229,-	p@chr5:33986219..33986229 -
Hg19::chr5:33988502..33988531,-	p@chr5:33988502..33988531 -
Hg19::chr6:101902072..101902081,-	p@chr6:101902072..101902081 -
Hg19::chr6:102074293..102074306,+	p@chr6:102074293..102074306 +
Hg19::chr6:102074319..102074330,+	p@chr6:102074319..102074330 +
Hg19::chr6:102074343..102074363,+	p@chr6:102074343..102074363 +
Hg19::chr6:102074381..102074390,+	p@chr6:102074381..102074390 +
Hg19::chr6:102074407..102074425,+	p@chr6:102074407..102074425 +
Hg19::chr6:102074434..102074437,+	p@chr6:102074434..102074437 +
Hg19::chr6:120555693..120555708,+	p@chr6:120555693..120555708 +
Hg19::chr6:131967608..131967633,+	p@chr6:131967608..131967633 +
Hg19::chr6:43858663..43858693,+	p4@LOC100132354
Hg19::chr6:43858741..43858765,+	p2@LOC100132354
Hg19::chr6:43858766..43858801,+	p1@LOC100132354
Hg19::chr7:130418367..130418376,+	p@chr7:130418367..130418376 +
Hg19::chr7:130418395..130418402,+	p@chr7:130418395..130418402 +
Hg19::chr7:157794309..157794344,-	p@chr7:157794309..157794344 -
Hg19::chr7:17978865..17978889,-	p@chr7:17978865..17978889 -
Hg19::chr7:17979403..17979425,+	p@chr7:17979403..17979425 +
Hg19::chr7:17980054..17980065,-	p3@SNX13
Hg19::chr7:18125931..18125935,+	p@chr7:18125931..18125935 +
Hg19::chr7:18126240..18126298,+	p15@HDAC9
Hg19::chr7:18126442..18126465,+	p9@HDAC9
Hg19::chr7:18126557..18126641,+	p6@HDAC9
Hg19::chr7:18127565..18127576,+	p1@ENST00000455069
Hg19::chr7:18206831..18206833,+	p@chr7:18206831..18206833 +
Hg19::chr7:18247180..18247182,+	p@chr7:18247180..18247182 +
Hg19::chr7:18390519..18390547,+	p@chr7:18390519..18390547 +
Hg19::chr7:18535224..18535233,+	p41@HDAC9
Hg19::chr7:18535300..18535311,+	p20@HDAC9
Hg19::chr7:18535321..18535343,+	p7@HDAC9
Hg19::chr7:18575650..18575653,-	p@chr7:18575650..18575653 -
Hg19::chr7:18587136..18587138,+	p@chr7:18587136..18587138 +
Hg19::chr7:18624926..18624945,+	p@chr7:18624926..18624945 +
Hg19::chr7:18625020..18625033,+	p@chr7:18625020..18625033 +
Hg19::chr7:18668902..18668905,+	p@chr7:18668902..18668905 +
Hg19::chr7:18672094..18672104,+	p@chr7:18672094..18672104 +
Hg19::chr7:18687532..18687536,+	p@chr7:18687532..18687536 +
Hg19::chr7:27224021..27224026,+	p17@HOXA11-AS1
Hg19::chr7:27282174..27282223,-	p1@ENST00000519050
Hg19::chr7:27282385..27282394,+	p3@EVX1
Hg19::chr7:27903656..27903678,-	p11@JAZF1
Hg19::chr7:29233305..29233342,+	p@chr7:29233305..29233342 +
Hg19::chr7:29334902..29334911,+	p@chr7:29334902..29334911 +
Hg19::chr7:73140837..73140841,-	p@chr7:73140837..73140841 -
Hg19::chr7:75909929..75909966,+	p@chr7:75909929..75909966 +
Hg19::chr7:75910322..75910332,+	p@chr7:75910322..75910332 +
Hg19::chr8:108266644..108266647,-	p@chr8:108266644..108266647 -
Hg19::chr8:108323457..108323466,-	p@chr8:108323457..108323466 -
Hg19::chr8:108323495..108323502,-	p@chr8:108323495..108323502 -
Hg19::chr8:108323562..108323573,-	p@chr8:108323562..108323573 -
Hg19::chr8:108323707..108323711,-	p@chr8:108323707..108323711 -
Hg19::chr8:108324027..108324036,-	p@chr8:108324027..108324036 -
Hg19::chr8:108446884..108446900,-	p@chr8:108446884..108446900 -
Hg19::chr8:108509590..108509613,-	p6@ANGPT1
Hg19::chr8:108509895..108509902,-	p16@ANGPT1
Hg19::chr8:108510224..108510248,-	p3@ANGPT1
Hg19::chr8:123583818..123583821,-	p@chr8:123583818..123583821 -
Hg19::chr8:20040601..20040630,-	p2@SLC18A1
Hg19::chr8:20040638..20040652,-	p1@SLC18A1
Hg19::chr8:20472433..20472439,-	p1@ENST00000516135
Hg19::chr8:38399534..38399540,-	p@chr8:38399534..38399540 -
Hg19::chr8:38411258..38411272,-	p@chr8:38411258..38411272 -
Hg19::chr8:49730848..49730871,+	p@chr8:49730848..49730871 +
Hg19::chr8:6698718..6698744,+	p@chr8:6698718..6698744 +
Hg19::chr8:6817717..6817731,-	p1@DEFA9P
Hg19::chr8:6887048..6887055,-	p1@DEFA11P
Hg19::chr8:6897005..6897008,-	p1@DEFA7P
Hg19::chr8:6914153..6914160,-	p2@DEFA5
Hg19::chr9:73778694..73778720,-	p@chr9:73778694..73778720 -
Hg19::chr9:73829940..73829948,-	p@chr9:73829940..73829948 -
Hg19::chr9:73881874..73881877,-	p@chr9:73881874..73881877 -
Hg19::chr9:73893947..73893951,-	p@chr9:73893947..73893951 -
Hg19::chr9:73894992..73894993,-	p@chr9:73894992..73894993 -
Hg19::chr9:73947041..73947056,-	p@chr9:73947041..73947056 -
Hg19::chr9:73947245..73947253,-	p@chr9:73947245..73947253 -
Hg19::chr9:74062623..74062652,-	p@chr9:74062623..74062652 -
Hg19::chr9:74062701..74062711,-	p@chr9:74062701..74062711 -
Hg19::chr9:74167593..74167609,-	p@chr9:74167593..74167609 -
Hg19::chr9:74167667..74167687,-	p@chr9:74167667..74167687 -
Hg19::chr9:74167724..74167739,-	p@chr9:74167724..74167739 -
Hg19::chr9:74167989..74167992,-	p@chr9:74167989..74167992 -
Hg19::chr9:74384373..74384388,-	p@chr9:74384373..74384388 -

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0016481	negative regulation of transcription	0.00569544948163178
GO:0045934	negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process	0.00569544948163178
GO:0031324	negative regulation of cellular metabolic process	0.00755964970404332
GO:0009892	negative regulation of metabolic process	0.00952977996252333
GO:0016564	transcription repressor activity	0.0151647357180119
GO:0007275	multicellular organismal development	0.0151647357180119
GO:0048523	negative regulation of cellular process	0.0157689292058636
GO:0006355	regulation of transcription, DNA-dependent	0.0157689292058636
GO:0004363	glutathione synthase activity	0.0157689292058636
GO:0048519	negative regulation of biological process	0.0157689292058636
GO:0006351	transcription, DNA-dependent	0.0157689292058636
GO:0032774	RNA biosynthetic process	0.0157689292058636
GO:0045449	regulation of transcription	0.021642745754459
GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process	0.0223548243104183
GO:0006350	transcription	0.0241386646810479
GO:0010468	regulation of gene expression	0.0241386646810479
GO:0042742	defense response to bacterium	0.0254107438310059
GO:0031323	regulation of cellular metabolic process	0.0254107438310059
GO:0003700	transcription factor activity	0.0261464457060413
GO:0009617	response to bacterium	0.0261464457060413
GO:0003714	transcription corepressor activity	0.0261464457060413
GO:0006357	regulation of transcription from RNA polymerase II promoter	0.0261464457060413
GO:0008134	transcription factor binding	0.0261464457060413
GO:0019222	regulation of metabolic process	0.0261464457060413
GO:0016070	RNA metabolic process	0.0261464457060413
GO:0005497	androgen binding	0.0263168210860954
GO:0048731	system development	0.0263168210860954
GO:0044451	nucleoplasm part	0.0263168210860954
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	0.0271229937447896
GO:0032502	developmental process	0.0281826313299467
GO:0008504	monoamine transmembrane transporter activity	0.0281826313299467
GO:0005515	protein binding	0.0295470862423253
GO:0015844	monoamine transport	0.0310627333598091
GO:0065007	biological regulation	0.0310627333598091
GO:0005654	nucleoplasm	0.0310627333598091
GO:0050794	regulation of cellular process	0.0350130822848958
GO:0045843	negative regulation of striated muscle development	0.0367532869569296
GO:0006750	glutathione biosynthetic process	0.0367532869569296
GO:0006952	defense response	0.0386664540593856
GO:0042221	response to chemical stimulus	0.0386664540593856
GO:0017053	transcriptional repressor complex	0.0425549775703636
GO:0032501	multicellular organismal process	0.0425615836320144
GO:0048856	anatomical structure development	0.0427035378600283
GO:0006366	transcription from RNA polymerase II promoter	0.0427035378600283
GO:0045892	negative regulation of transcription, DNA-dependent	0.0427035378600283
GO:0051707	response to other organism	0.0427035378600283
GO:0050789	regulation of biological process	0.0427035378600283
GO:0005667	transcription factor complex	0.0427035378600283
GO:0050832	defense response to fungus	0.0427035378600283
GO:0016202	regulation of striated muscle development	0.0451811701326321
GO:0045893	positive regulation of transcription, DNA-dependent	0.0451811701326321
GO:0031981	nuclear lumen	0.0451811701326321
GO:0050821	protein stabilization	0.0451811701326321
GO:0016566	specific transcriptional repressor activity	0.0451811701326321
GO:0007417	central nervous system development	0.0472137525682012
GO:0007399	nervous system development	0.0472205833852633

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br>disease_data<br>

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Uber Anatomy

Ontology term	p-value	n
adult organism	1.68e-31	115
central nervous system	2.40e-27	82
regional part of nervous system	5.84e-27	94
nervous system	5.84e-27	94
neural tube	2.17e-24	57
neural rod	2.17e-24	57
future spinal cord	2.17e-24	57
neural keel	2.17e-24	57
brain	5.72e-22	69
future brain	5.72e-22	69
anterior neural tube	1.49e-20	42
regional part of forebrain	3.80e-20	41
forebrain	3.80e-20	41
future forebrain	3.80e-20	41
regional part of brain	6.74e-20	59
ectoderm	1.75e-17	173
presumptive ectoderm	1.75e-17	173
ectoderm-derived structure	1.08e-16	169
gray matter	1.67e-16	34
brain grey matter	1.67e-16	34
telencephalon	1.97e-16	34
regional part of telencephalon	6.47e-16	33
cerebral hemisphere	1.50e-15	32
neurectoderm	2.13e-14	90
regional part of cerebral cortex	1.01e-13	22
neural plate	1.24e-13	86
presumptive neural plate	1.24e-13	86
anterior region of body	1.33e-13	129
craniocervical region	1.33e-13	129
cerebral cortex	2.21e-13	25
pallium	2.21e-13	25
head	4.99e-13	123
neocortex	8.50e-13	20
pre-chordal neural plate	8.89e-10	61
organ	4.67e-07	511

Disease

Ontology term	p-value	n
cell type cancer	3.24e-07	143

Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
{{{tfbs_overrepresentation_jaspar}}}

ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data

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No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data

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