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|id=CL:0000898
|id=CL:0000898
|name=naive T cell
|name=naive T cell
|namespace=efo
|namespace=cell;;efo
|def="Mature T cell not yet exposed to antigen with the phenotype CCR7-positive, CD45RA-positive, and CD127-positive. This cell type is also described as being CD25-negative, CD62L-high and CD44-low." [GO_REF:0000031, GOC:add, GOC:pam, GOC:tfm, PMID:19100699]
|def="Mature T cell not yet exposed to antigen with the phenotype CCR7-positive, CD45RA-positive, and CD127-positive. This cell type is also described as being CD25-negative, CD62L-high and CD44-low." [GO_REF:0000031, GOC:add, GOC:pam, GOC:tfm, PMID:19100699]
|xref=
|xref=
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|obo_creation_date=
|subset=
|subset=
|adjacent_to=
|derives_from=
|derives_from=
|develops_from=
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|located_in=
|located_in=
|part_of=
|part_of=
|property_value=IAO:0000412 http://purl.obolibrary.org/obo/cl.owl;;IAO:0000412 http://purl.obolibrary.org/obo/efo.obo.owl
|property_value=IAO:0000412 http://purl.obolibrary.org/obo/cl.owl;;IAO:0000412 http://purl.obolibrary.org/obo/efo.owl
|is_obsolete=
|is_obsolete=
|preceded_by=
|preceded_by=
}}
}}

Revision as of 17:26, 26 June 2012

Name:naive T cell
Namespace:cell;;efo
Definition:"Mature T cell not yet exposed to antigen with the phenotype CCR7-positive, CD45RA-positive, and CD127-positive. This cell type is also described as being CD25-negative, CD62L-high and CD44-low." [GO_REF:0000031, GOC:add, GOC:pam, GOC:tfm, PMID:19100699]
Synonyms: "naive T lymphocyte" EXACT []
"naive T-cell" EXACT []
"naive T-lymphocyte" EXACT []


Ontology association <br>Each term has an is_a parent in the Cell ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to Cell ontologies.<br><br>link to ontology dataset<br>data

Parents

is_a:CL:0002419(mature T cell)



Children


is a:CL:0000895 (naive thymus-derived CD4-positive, alpha-beta T cell),CL:0002677 (naive regulatory T cell)
disjoint from:CL:0000813 (memory T cell)

Ontology Tree: Loaded from BioPortal

Ontorolgy tree(Small window open)


FF samples<br>It includes FANTOM5 samples that overlay the Cell ontology.

Human (Homo sapiens)

  • 11780-124A7 (CD4+CD25+CD45RA+ naive regulatory T cells, donor1)
  • 11782-124A9 (CD4+CD25+CD45RA- memory regulatory T cells, donor1)
  • 11786-124B4 (CD4+CD25-CD45RA- memory conventional T cells, donor1)
  • 11813-124E4 (CD4+CD25-CD44- naive conventional T cells, pool1 (C57BL_6J))
  • 11815-124E6 (CD4+CD25-CD44- naive conventional T cells, antiCD3_CD28 stimulation, 06hr, pool1 (C57BL_6J))
  • 11816-124E7 (CD4+CD25-CD44- naive conventional T cells, PMA and ionomycin stimulation, 02hr, pool1 (C57BL_6J))
  • 11817-124E8 (CD4+CD25-CD44- naive conventional T cells, pool2 (Balb_cAJcl))
  • 11819-124F1 (CD4+CD25-CD44- naive conventional T cells, antiCD3_CD28 stimulation, 06hr, pool2 (Balb_cAJcl))
  • 11820-124F2 (CD4+CD25-CD44- naive conventional T cells, PMA and ionomycin stimulation, 02hr, pool2 (Balb_cAJcl))

Mouse (Mus musculus)

  • 11780-124A7 (CD4+CD25+CD45RA+ naive regulatory T cells, donor1)
  • 11782-124A9 (CD4+CD25+CD45RA- memory regulatory T cells, donor1)
  • 11786-124B4 (CD4+CD25-CD45RA- memory conventional T cells, donor1)
  • 11813-124E4 (CD4+CD25-CD44- naive conventional T cells, pool1 (C57BL_6J))
  • 11815-124E6 (CD4+CD25-CD44- naive conventional T cells, antiCD3_CD28 stimulation, 06hr, pool1 (C57BL_6J))
  • 11816-124E7 (CD4+CD25-CD44- naive conventional T cells, PMA and ionomycin stimulation, 02hr, pool1 (C57BL_6J))
  • 11817-124E8 (CD4+CD25-CD44- naive conventional T cells, pool2 (Balb_cAJcl))
  • 11819-124F1 (CD4+CD25-CD44- naive conventional T cells, antiCD3_CD28 stimulation, 06hr, pool2 (Balb_cAJcl))
  • 11820-124F2 (CD4+CD25-CD44- naive conventional T cells, PMA and ionomycin stimulation, 02hr, pool2 (Balb_cAJcl))


Enrichment analysis: top 100 FFCP enriched with this ontology termTOP 100 FANTOM5 Cage Peaks enriched with CL:0000898 (naive T cell), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data

P-valueFFCPShort description
6.24e-88FFCP PHASE1:Hg19::chr1:113160702..113160706,-#_0e6a555c017994ed14f9f27d9b9f697fp21@ST7L
6.24e-88FFCP PHASE2:Hg19::chr1:113160702..113160706,-#_0e6a555c017994ed14f9f27d9b9f697fp21@ST7L
1.36e-86FFCP PHASE1:Mm9::chr13:30878406..30878419,+#_45c0a2126c7877feb5d999ce26f98663p@chr13:30878406..30878419, +
1.36e-86FFCP PHASE2:Mm9::chrX:54476786..54476810,+#_45c0a2126c7877feb5d999ce26f98663p@chrX:54476786..54476810, +
1.36e-86FFCP PHASE1:Mm9::chrX:54476786..54476810,+#_45c0a2126c7877feb5d999ce26f98663p@chrX:54476786..54476810, +
1.36e-86FFCP PHASE2:Mm9::chr13:30878406..30878419,+#_45c0a2126c7877feb5d999ce26f98663p@chr13:30878406..30878419, +
1.01e-74FFCP PHASE1:Mm9::chr16:52032670..52032685,+#_9884e2aa3b61967731720194b725a5b9p@chr16:52032670..52032685, +
1.01e-74FFCP PHASE2:Mm9::chr16:52032670..52032685,+#_9884e2aa3b61967731720194b725a5b9p@chr16:52032670..52032685, +
1.66e-74FFCP PHASE1:Hg19::chr8:1709009..1709019,-#_8677c07e684fdc4afc5a720fab195413p1@BC025336
1.66e-74FFCP PHASE2:Hg19::chr8:1709009..1709019,-#_8677c07e684fdc4afc5a720fab195413p1@BC025336
2.41e-74FFCP PHASE2:Mm9::chr16:93777453..93777464,+#_5bc897c4c8d830c640d716873849f2aep@chr16:93777453..93777464, +
2.41e-74FFCP PHASE1:Mm9::chr16:93777453..93777464,+#_5bc897c4c8d830c640d716873849f2aep@chr16:93777453..93777464, +
2.41e-74FFCP PHASE2:Mm9::chr14:54795946..54795960,+#_5bc897c4c8d830c640d716873849f2aep1@ENSMUST00000103701
2.41e-74FFCP PHASE1:Mm9::chr14:54795946..54795960,+#_5bc897c4c8d830c640d716873849f2aep1@ENSMUST00000103701
2.48e-72FFCP PHASE1:Mm9::chr15:80403112..80403122,+#_e0fbc23f46ccd6199e51917edd62aa44p12@Grap2
2.48e-72FFCP PHASE2:Mm9::chr14:54827490..54827502,+#_e0fbc23f46ccd6199e51917edd62aa44p@chr14:54827490..54827502, +
2.48e-72FFCP PHASE1:Mm9::chr11:11587720..11587735,+#_e0fbc23f46ccd6199e51917edd62aa44p@chr11:11587720..11587735, +
2.48e-72FFCP PHASE2:Mm9::chr11:11587720..11587735,+#_e0fbc23f46ccd6199e51917edd62aa44p@chr11:11587720..11587735, +
2.48e-72FFCP PHASE1:Mm9::chr13:30853488..30853499,+#_e0fbc23f46ccd6199e51917edd62aa44p@chr13:30853488..30853499, +
2.48e-72FFCP PHASE1:Mm9::chr14:54827490..54827502,+#_e0fbc23f46ccd6199e51917edd62aa44p@chr14:54827490..54827502, +
2.48e-72FFCP PHASE2:Mm9::chr14:122362270..122362291,-#_e0fbc23f46ccd6199e51917edd62aa44p@chr14:122362270..122362291, -
2.48e-72FFCP PHASE2:Mm9::chr11:11592840..11592849,+#_e0fbc23f46ccd6199e51917edd62aa44p@chr11:11592840..11592849, +
2.48e-72FFCP PHASE2:Mm9::chr13:30853488..30853499,+#_e0fbc23f46ccd6199e51917edd62aa44p@chr13:30853488..30853499, +
2.48e-72FFCP PHASE1:Mm9::chr11:11592840..11592849,+#_e0fbc23f46ccd6199e51917edd62aa44p@chr11:11592840..11592849, +
2.48e-72FFCP PHASE2:Mm9::chr15:80403112..80403122,+#_e0fbc23f46ccd6199e51917edd62aa44p12@Grap2
2.48e-72FFCP PHASE1:Mm9::chr14:122362270..122362291,-#_e0fbc23f46ccd6199e51917edd62aa44p@chr14:122362270..122362291, -
7.85e-67FFCP PHASE1:Hg19::chr8:1708601..1708607,+#_2d481c41ea5db668b3d3a0901775417ap@chr8:1708601..1708607, +
7.85e-67FFCP PHASE2:Hg19::chr8:1708601..1708607,+#_2d481c41ea5db668b3d3a0901775417ap@chr8:1708601..1708607, +
1.23e-66FFCP PHASE2:Hg19::chrX:153238522..153238533,-#_0693803d27b5a4e14ac753d07b7e83bep@chrX:153238522..153238533, -
1.23e-66FFCP PHASE1:Hg19::chrX:153238522..153238533,-#_0693803d27b5a4e14ac753d07b7e83bep@chrX:153238522..153238533, -
1.71e-66FFCP PHASE2:Hg19::chr11:111410267..111410269,+#_15dbfbc0ec1948d3f204290393d22a8ap@chr11:111410267..111410269, +
1.71e-66FFCP PHASE1:Hg19::chr11:111410267..111410269,+#_15dbfbc0ec1948d3f204290393d22a8ap@chr11:111410267..111410269, +
1.92e-66FFCP PHASE1:Hg19::chr3:66444556..66444563,-#_cb7bb655692e46c1f1814a28b93e1d9bp@chr3:66444556..66444563, -
1.92e-66FFCP PHASE2:Hg19::chr3:66444556..66444563,-#_cb7bb655692e46c1f1814a28b93e1d9bp@chr3:66444556..66444563, -
2.39e-66FFCP PHASE2:Hg19::chr3:73015629..73015632,+#_42563d1820aa30a9c82a335dfbbeedc6p@chr3:73015629..73015632, +
2.39e-66FFCP PHASE1:Hg19::chr3:73015629..73015632,+#_42563d1820aa30a9c82a335dfbbeedc6p@chr3:73015629..73015632, +
3.01e-66FFCP PHASE2:Hg19::chr10:6337053..6337076,+#_645827c27322427a1add7d3bf330a7dbp@chr10:6337053..6337076, +
3.01e-66FFCP PHASE1:Hg19::chr10:6337053..6337076,+#_645827c27322427a1add7d3bf330a7dbp@chr10:6337053..6337076, +
3.35e-66FFCP PHASE1:Hg19::chr10:116301431..116301440,+#_104dac11964e6565862d3770b6001925p@chr10:116301431..116301440, +
3.35e-66FFCP PHASE1:Hg19::chr12:53039683..53039695,+#_104dac11964e6565862d3770b6001925p@chr12:53039683..53039695, +
3.35e-66FFCP PHASE2:Hg19::chr10:116301431..116301440,+#_104dac11964e6565862d3770b6001925p@chr10:116301431..116301440, +
3.35e-66FFCP PHASE2:Hg19::chr12:53039683..53039695,+#_104dac11964e6565862d3770b6001925p@chr12:53039683..53039695, +
4.68e-66FFCP PHASE1:Hg19::chr6:167527627..167527634,-#_e2d64b51206373f86df1ea6da43002d8p@chr6:167527627..167527634, -
4.68e-66FFCP PHASE2:Hg19::chr6:167527627..167527634,-#_e2d64b51206373f86df1ea6da43002d8p@chr6:167527627..167527634, -
6.53e-66FFCP PHASE2:Hg19::chr12:8472866..8472868,-#_d6f8e3e64d83caea80435481f4abfb59p@chr12:8472866..8472868, -
6.53e-66FFCP PHASE1:Hg19::chr12:8472866..8472868,-#_d6f8e3e64d83caea80435481f4abfb59p@chr12:8472866..8472868, -
1.05e-65FFCP PHASE1:Mm9::chr14:53242248..53242261,+#_6bdd723be00fda3b84690ee8bae866a6p@chr14:53242248..53242261, +
1.05e-65FFCP PHASE2:Mm9::chr14:53242248..53242261,+#_6bdd723be00fda3b84690ee8bae866a6p@chr14:53242248..53242261, +
1.74e-65FFCP PHASE1:Mm9::chr5:123439274..123439290,+#_02670d72da72016cabbf5861daafbbf7p4@ENSMUST00000148466, p4@uc008zmw.1
1.74e-65FFCP PHASE2:Mm9::chr5:123439274..123439290,+#_02670d72da72016cabbf5861daafbbf7p4@ENSMUST00000148466, p4@uc008zmw.1
2.25e-65FFCP PHASE2:Mm9::chr15:80403104..80403111,+#_fca3ff5343d0480ea74e60b6096e6f40p10@Grap2
2.25e-65FFCP PHASE2:Mm9::chr1:140069290..140069308,+#_fca3ff5343d0480ea74e60b6096e6f40p@chr1:140069290..140069308, +
2.25e-65FFCP PHASE2:Mm9::chr5:123465978..123465989,-#_fca3ff5343d0480ea74e60b6096e6f40p@chr5:123465978..123465989, -
2.25e-65FFCP PHASE1:Mm9::chr5:123465978..123465989,-#_fca3ff5343d0480ea74e60b6096e6f40p@chr5:123465978..123465989, -
2.25e-65FFCP PHASE1:Mm9::chr15:80403104..80403111,+#_fca3ff5343d0480ea74e60b6096e6f40p10@Grap2
2.25e-65FFCP PHASE1:Mm9::chr1:140069290..140069308,+#_fca3ff5343d0480ea74e60b6096e6f40p@chr1:140069290..140069308, +
2.9e-65FFCP PHASE2:Mm9::chr11:46200242..46200255,+#_b6f83c645f3ed464bd5a52ff2e4cfdf9p@chr11:46200242..46200255, +
2.9e-65FFCP PHASE2:Mm9::chr14:54817583..54817593,-#_b6f83c645f3ed464bd5a52ff2e4cfdf9p@chr14:54817583..54817593, -
2.9e-65FFCP PHASE1:Mm9::chr11:46200242..46200255,+#_b6f83c645f3ed464bd5a52ff2e4cfdf9p@chr11:46200242..46200255, +
2.9e-65FFCP PHASE1:Mm9::chr14:54817583..54817593,-#_b6f83c645f3ed464bd5a52ff2e4cfdf9p@chr14:54817583..54817593, -
2.9e-65FFCP PHASE1:Mm9::chr6:41504409..41504422,-#_b6f83c645f3ed464bd5a52ff2e4cfdf9p@chr6:41504409..41504422, -
2.9e-65FFCP PHASE2:Mm9::chr6:41504409..41504422,-#_b6f83c645f3ed464bd5a52ff2e4cfdf9p@chr6:41504409..41504422, -
3.74e-65FFCP PHASE2:Mm9::chr4:32328217..32328228,-#_2ed236a925482c8ba8f6bc611fe4daf2p@chr4:32328217..32328228, -
3.74e-65FFCP PHASE1:Mm9::chr4:32328217..32328228,-#_2ed236a925482c8ba8f6bc611fe4daf2p@chr4:32328217..32328228, -
6.21e-65FFCP PHASE2:Mm9::chr11:46200110..46200124,-#_880fdaf57160532714bf01e116816c8cp@chr11:46200110..46200124, -
6.21e-65FFCP PHASE1:Mm9::chr5:123465955..123465966,-#_880fdaf57160532714bf01e116816c8cp@chr5:123465955..123465966, -
6.21e-65FFCP PHASE1:Mm9::chr13:105412781..105412798,+#_880fdaf57160532714bf01e116816c8cp@chr13:105412781..105412798, +
6.21e-65FFCP PHASE2:Mm9::chr5:123465955..123465966,-#_880fdaf57160532714bf01e116816c8cp@chr5:123465955..123465966, -
6.21e-65FFCP PHASE1:Mm9::chr11:46200110..46200124,-#_880fdaf57160532714bf01e116816c8cp@chr11:46200110..46200124, -
6.21e-65FFCP PHASE2:Mm9::chr13:105412781..105412798,+#_880fdaf57160532714bf01e116816c8cp@chr13:105412781..105412798, +
1.0e-60FFCP PHASE1:Mm9::chr2:11097490..11097500,+#_73ed6a76eecb8ff1e346e3368bca33dep@chr2:11097490..11097500, +
1.0e-60FFCP PHASE2:Mm9::chr2:11097490..11097500,+#_73ed6a76eecb8ff1e346e3368bca33dep@chr2:11097490..11097500, +
1.33e-60FFCP PHASE2:Mm9::chr7:150943007..150943022,+#_903c4cfa9568c292b2f6400bab9dc9e5p@chr7:150943007..150943022, +
1.33e-60FFCP PHASE2:Mm9::chr5:108160486..108160515,-#_903c4cfa9568c292b2f6400bab9dc9e5p@chr5:108160486..108160515, -
1.33e-60FFCP PHASE1:Mm9::chr12:70398221..70398232,-#_903c4cfa9568c292b2f6400bab9dc9e5p@chr12:70398221..70398232, -
1.33e-60FFCP PHASE2:Mm9::chr12:70398221..70398232,-#_903c4cfa9568c292b2f6400bab9dc9e5p@chr12:70398221..70398232, -
1.33e-60FFCP PHASE1:Mm9::chr7:150943007..150943022,+#_903c4cfa9568c292b2f6400bab9dc9e5p@chr7:150943007..150943022, +
1.33e-60FFCP PHASE1:Mm9::chr10:128157769..128157772,-#_903c4cfa9568c292b2f6400bab9dc9e5p@chr10:128157769..128157772, -
1.33e-60FFCP PHASE1:Mm9::chr5:108160486..108160515,-#_903c4cfa9568c292b2f6400bab9dc9e5p@chr5:108160486..108160515, -
1.33e-60FFCP PHASE2:Mm9::chr10:128157769..128157772,-#_903c4cfa9568c292b2f6400bab9dc9e5p@chr10:128157769..128157772, -
1.77e-60FFCP PHASE1:Mm9::chr14:53414758..53414769,+#_a1fcf65d83d447385839a18373ec4976p1@ENSMUST00000103582
1.77e-60FFCP PHASE2:Mm9::chr14:53414758..53414769,+#_a1fcf65d83d447385839a18373ec4976p1@ENSMUST00000103582
2.34e-60FFCP PHASE2:Mm9::chr2:73290853..73290866,+#_c12dd5dc7f0874a0c2d3f21568f13981p@chr2:73290853..73290866, +
2.34e-60FFCP PHASE1:Mm9::chr2:73290853..73290866,+#_c12dd5dc7f0874a0c2d3f21568f13981p@chr2:73290853..73290866, +
4.1e-60FFCP PHASE1:Mm9::chr1:138476217..138476228,+#_e0d96801021be733a0165d0a127ce642p@chr1:138476217..138476228, +
4.1e-60FFCP PHASE1:Mm9::chr9:14708434..14708444,-#_e0d96801021be733a0165d0a127ce642p8@Folr4
4.1e-60FFCP PHASE1:Mm9::chr2:11181142..11181148,-#_e0d96801021be733a0165d0a127ce642p@chr2:11181142..11181148, -
4.1e-60FFCP PHASE2:Mm9::chr9:14708434..14708444,-#_e0d96801021be733a0165d0a127ce642p8@Folr4
4.1e-60FFCP PHASE2:Mm9::chr2:11181142..11181148,-#_e0d96801021be733a0165d0a127ce642p@chr2:11181142..11181148, -
4.1e-60FFCP PHASE2:Mm9::chr1:138476217..138476228,+#_e0d96801021be733a0165d0a127ce642p@chr1:138476217..138476228, +
6.68e-60FFCP PHASE1:Hg19::chr13:40765017..40765053,-#_53410b305f867886d7adfec7e6441c55p@chr13:40765017..40765053, -
6.68e-60FFCP PHASE2:Hg19::chr13:40765017..40765053,-#_53410b305f867886d7adfec7e6441c55p@chr13:40765017..40765053, -
8.17e-60FFCP PHASE2:Hg19::chr1:118201616..118201641,+#_38d88d3f3906b50debc4125b89b0f296p@chr1:118201616..118201641, +
8.17e-60FFCP PHASE1:Hg19::chr1:118201616..118201641,+#_38d88d3f3906b50debc4125b89b0f296p@chr1:118201616..118201641, +
6.9e-59FFCP PHASE1:Mm9::chr11:87558695..87558707,+#_f25b2cf476009afcc04e46b8a6917950p@chr11:87558695..87558707, +
6.9e-59FFCP PHASE2:Mm9::chrX:54465221..54465232,+#_f25b2cf476009afcc04e46b8a6917950p4@Cd40lg
6.9e-59FFCP PHASE1:Mm9::chrX:54477240..54477286,+#_f25b2cf476009afcc04e46b8a6917950p@chrX:54477240..54477286, +
6.9e-59FFCP PHASE1:Mm9::chrX:54465221..54465232,+#_f25b2cf476009afcc04e46b8a6917950p4@Cd40lg
6.9e-59FFCP PHASE2:Mm9::chr11:87558695..87558707,+#_f25b2cf476009afcc04e46b8a6917950p@chr11:87558695..87558707, +
6.9e-59FFCP PHASE2:Mm9::chrX:54477240..54477286,+#_f25b2cf476009afcc04e46b8a6917950p@chrX:54477240..54477286, +

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