Coexpression cluster:C515: Difference between revisions
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|gostat_on_coexpression_clusters=GO:0031705!bombesin receptor binding!0.000917422190823815!1906$GO:0031583!G-protein signaling, phospholipase D activating pathway!0.000917422190823815!1906$GO:0043179!rhythmic excitation!0.000917422190823815!1906$GO:0031708!endothelin B receptor binding!0.000917422190823815!1906$GO:0031707!endothelin A receptor binding!0.000917422190823815!1906$GO:0060024!rhythmic synaptic transmission!0.000917422190823815!1906$GO:0030815!negative regulation of cAMP metabolic process!0.00137613328623572!1906$GO:0030818!negative regulation of cAMP biosynthetic process!0.00137613328623572!1906$GO:0030809!negative regulation of nucleotide biosynthetic process!0.00137613328623572!1906$GO:0030803!negative regulation of cyclic nucleotide biosynthetic process!0.00137613328623572!1906$GO:0042474!middle ear morphogenesis!0.00137613328623572!1906$GO:0030800!negative regulation of cyclic nucleotide metabolic process!0.00137613328623572!1906$GO:0030147!natriuresis!0.00157272375569797!1906$GO:0030817!regulation of cAMP biosynthetic process!0.00157272375569797!1906$GO:0003091!renal water homeostasis!0.00157272375569797!1906$GO:0030146!diuresis!0.00157272375569797!1906$GO:0030802!regulation of cyclic nucleotide biosynthetic process!0.00157272375569797!1906$GO:0030808!regulation of nucleotide biosynthetic process!0.00157272375569797!1906$GO:0051482!elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)!0.00157272375569797!1906$GO:0045980!negative regulation of nucleotide metabolic process!0.00157272375569797!1906$GO:0030814!regulation of cAMP metabolic process!0.00157272375569797!1906$GO:0030799!regulation of cyclic nucleotide metabolic process!0.00167529269628697!1906$GO:0030104!water homeostasis!0.00167529269628697!1906$GO:0018987!osmoregulation!0.00183484438164763!1906$GO:0003014!renal system process!0.00183484438164763!1906$GO:0019229!regulation of vasoconstriction!0.00183484438164763!1906$GO:0051899!membrane depolarization!0.00183484438164763!1906$GO:0006140!regulation of nucleotide metabolic process!0.00196590469462246!1906$GO:0001569!patterning of blood vessels!0.00201832881981239!1906$GO:0046888!negative regulation of hormone secretion!0.00201832881981239!1906$GO:0009405!pathogenesis!0.0023083526091696!1906$GO:0014032!neural crest cell development!0.00233525648573335!1906$GO:0014033!neural crest cell differentiation!0.00233525648573335!1906$GO:0042310!vasoconstriction!0.00251635800911675!1906$GO:0050804!regulation of synaptic transmission!0.00251635800911675!1906$GO:0051048!negative regulation of secretion!0.00259936287400081!1906$GO:0051969!regulation of transmission of nerve impulse!0.00260741043707821!1906$GO:0007589!fluid secretion!0.00260741043707821!1906$GO:0046883!regulation of hormone secretion!0.00261465324384787!1906$GO:0006171!cAMP biosynthetic process!0.00261465324384787!1906$GO:0046058!cAMP metabolic process!0.00295365193143277!1906$GO:0048762!mesenchymal cell differentiation!0.00307229756927045!1906$GO:0014031!mesenchymal cell development!0.00307229756927045!1906$GO:0031644!regulation of neurological process!0.00312757565053574!1906$GO:0009880!embryonic pattern specification!0.00314544751139594!1906$GO:0048754!branching morphogenesis of a tube!0.00314544751139594!1906$GO:0009953!dorsal/ventral pattern formation!0.00314544751139594!1906$GO:0007585!respiratory gaseous exchange!0.00314544751139594!1906$GO:0015758!glucose transport!0.00314544751139594!1906$GO:0042471!ear morphogenesis!0.00314544751139594!1906$GO:0042391!regulation of membrane potential!0.00314544751139594!1906$GO:0001763!morphogenesis of a branching structure!0.00314544751139594!1906$GO:0008645!hexose transport!0.00314544751139594!1906$GO:0044403!symbiosis, encompassing mutualism through parasitism!0.00314544751139594!1906$GO:0044419!interspecies interaction between organisms!0.00314544751139594!1906$GO:0015749!monosaccharide transport!0.00314544751139594!1906$GO:0006885!regulation of pH!0.00318683497865115!1906$GO:0046879!hormone secretion!0.00322679529186308!1906$GO:0051216!cartilage development!0.00335869819013465!1906$GO:0007205!protein kinase C activation!0.0034862043251305!1906$GO:0009190!cyclic nucleotide biosynthetic process!0.00355677526288618!1906$GO:0007588!excretion!0.00355677526288618!1906$GO:0035150!regulation of tube size!0.00355677526288618!1906$GO:0050880!regulation of blood vessel size!0.00355677526288618!1906$GO:0043583!ear development!0.00355677526288618!1906$GO:0003018!vascular process in circulatory system!0.00358628674594764!1906$GO:0001666!response to hypoxia!0.00394354613369043!1906$GO:0009187!cyclic nucleotide metabolic process!0.00398879213401659!1906$GO:0001701!in utero embryonic development!0.00398879213401659!1906$GO:0009890!negative regulation of biosynthetic process!0.00401044557702982!1906$GO:0008217!regulation of blood pressure!0.00426407497143464!1906$GO:0051046!regulation of secretion!0.00451065910488376!1906$GO:0051480!cytosolic calcium ion homeostasis!0.00506996473876319!1906$GO:0003001!generation of a signal involved in cell-cell signaling!0.00506996473876319!1906$GO:0007204!elevation of cytosolic calcium ion concentration!0.00506996473876319!1906$GO:0032147!activation of protein kinase activity!0.00506996473876319!1906$GO:0035239!tube morphogenesis!0.00600494524902861!1906$GO:0007423!sensory organ development!0.00605498645943718!1906$GO:0003002!regionalization!0.00605498645943718!1906$GO:0007200!G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)!0.00605498645943718!1906$GO:0048598!embryonic morphogenesis!0.00622536486630446!1906$GO:0007507!heart development!0.00622536486630446!1906$GO:0009792!embryonic development ending in birth or egg hatching!0.00622536486630446!1906$GO:0043009!chordate embryonic development!0.00622536486630446!1906$GO:0001664!G-protein-coupled receptor binding!0.0067349582008713!1906$GO:0008643!carbohydrate transport!0.00710468812893792!1906$GO:0006874!cellular calcium ion homeostasis!0.00723629638155414!1906$GO:0055074!calcium ion homeostasis!0.00723629638155414!1906$GO:0035295!tube development!0.00723629638155414!1906$GO:0006875!cellular metal ion homeostasis!0.00739856605503077!1906$GO:0055065!metal ion homeostasis!0.00739856605503077!1906$GO:0007389!pattern specification process!0.00739856605503077!1906$GO:0050878!regulation of body fluid levels!0.00739856605503077!1906$GO:0048015!phosphoinositide-mediated signaling!0.00747457658629087!1906$GO:0001525!angiogenesis!0.00747457658629087!1906$GO:0045860!positive regulation of protein kinase activity!0.00808478305663487!1906$GO:0033674!positive regulation of kinase activity!0.00817167807084306!1906$GO:0051347!positive regulation of transferase activity!0.00817339770006672!1906$GO:0048514!blood vessel morphogenesis!0.00817339770006672!1906$GO:0048646!anatomical structure formation!0.00842193571176262!1906$GO:0008015!blood circulation!0.00863456179598885!1906$GO:0003013!circulatory system process!0.00863456179598885!1906$GO:0001568!blood vessel development!0.00876449937641393!1906$GO:0001944!vasculature development!0.00878608175058193!1906$GO:0030005!cellular di-, tri-valent inorganic cation homeostasis!0.00943634253418782!1906$GO:0055066!di-, tri-valent inorganic cation homeostasis!0.00950310910872217!1906$GO:0030003!cellular cation homeostasis!0.0102888469998933!1906$GO:0055080!cation homeostasis!0.010346483596513!1906$GO:0001501!skeletal development!0.0105545635531474!1906$GO:0005179!hormone activity!0.0107611143464199!1906$GO:0009889!regulation of biosynthetic process!0.0107611143464199!1906$GO:0008284!positive regulation of cell proliferation!0.0111502081653971!1906$GO:0005625!soluble fraction!0.0111502081653971!1906$GO:0009790!embryonic development!0.0111502081653971!1906$GO:0045859!regulation of protein kinase activity!0.0111502081653971!1906$GO:0055082!cellular chemical homeostasis!0.0111502081653971!1906$GO:0006873!cellular ion homeostasis!0.0111502081653971!1906$GO:0043549!regulation of kinase activity!0.0112889578057303!1906$GO:0051338!regulation of transferase activity!0.0114253755193352!1906$GO:0009165!nucleotide biosynthetic process!0.0116459544223585!1906$GO:0043085!positive regulation of catalytic activity!0.0116459544223585!1906$GO:0050801!ion homeostasis!0.0119936169336967!1906$GO:0019932!second-messenger-mediated signaling!0.0119936169336967!1906$GO:0051239!regulation of multicellular organismal process!0.0122964167834611!1906$GO:0007268!synaptic transmission!0.0127705168962675!1906$GO:0048878!chemical homeostasis!0.0131934048394663!1906$GO:0009888!tissue development!0.0132195481039967!1906$GO:0045934!negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process!0.0137183286971624!1906$GO:0019226!transmission of nerve impulse!0.0140813638591562!1906$GO:0051704!multi-organism process!0.0141000733635845!1906$GO:0009117!nucleotide metabolic process!0.0142865745746609!1906$GO:0009887!organ morphogenesis!0.0150957651399192!1906$GO:0055086!nucleobase, nucleoside and nucleotide metabolic process!0.015189200482662!1906$GO:0019725!cellular homeostasis!0.0153311441666558!1906$GO:0007243!protein kinase cascade!0.0153311441666558!1906$GO:0031324!negative regulation of cellular metabolic process!0.0154207877075238!1906$GO:0046903!secretion!0.0154287644354604!1906$GO:0009892!negative regulation of metabolic process!0.0173911337043123!1906$GO:0042127!regulation of cell proliferation!0.0185728492444476!1906$GO:0042592!homeostatic process!0.0188726850683756!1906$GO:0005615!extracellular space!0.0206127198619138!1906$GO:0050790!regulation of catalytic activity!0.0234524123428905!1906$GO:0007267!cell-cell signaling!0.0246356728165276!1906$GO:0065009!regulation of a molecular function!0.0256495954184492!1906$GO:0008283!cell proliferation!0.0282819116757411!1906$GO:0000267!cell fraction!0.034007458196839!1906$GO:0044421!extracellular region part!0.034075681373456!1906$GO:0065008!regulation of biological quality!0.0352437893978223!1906$GO:0048522!positive regulation of cellular process!0.0352437893978223!1906$GO:0005102!receptor binding!0.0380546724753719!1906$GO:0009653!anatomical structure morphogenesis!0.0381671933957299!1906$GO:0048518!positive regulation of biological process!0.0384593039469036!1906$GO:0048523!negative regulation of cellular process!0.040783586482986!1906$GO:0048513!organ development!0.040783586482986!1906$GO:0048519!negative regulation of biological process!0.0419765043698226!1906$GO:0006950!response to stress!0.0431188429687193!1906$GO:0048468!cell development!0.0435454150701852!1906$GO:0050877!neurological system process!0.0442104592464084!1906 | |gostat_on_coexpression_clusters=GO:0031705!bombesin receptor binding!0.000917422190823815!1906$GO:0031583!G-protein signaling, phospholipase D activating pathway!0.000917422190823815!1906$GO:0043179!rhythmic excitation!0.000917422190823815!1906$GO:0031708!endothelin B receptor binding!0.000917422190823815!1906$GO:0031707!endothelin A receptor binding!0.000917422190823815!1906$GO:0060024!rhythmic synaptic transmission!0.000917422190823815!1906$GO:0030815!negative regulation of cAMP metabolic process!0.00137613328623572!1906$GO:0030818!negative regulation of cAMP biosynthetic process!0.00137613328623572!1906$GO:0030809!negative regulation of nucleotide biosynthetic process!0.00137613328623572!1906$GO:0030803!negative regulation of cyclic nucleotide biosynthetic process!0.00137613328623572!1906$GO:0042474!middle ear morphogenesis!0.00137613328623572!1906$GO:0030800!negative regulation of cyclic nucleotide metabolic process!0.00137613328623572!1906$GO:0030147!natriuresis!0.00157272375569797!1906$GO:0030817!regulation of cAMP biosynthetic process!0.00157272375569797!1906$GO:0003091!renal water homeostasis!0.00157272375569797!1906$GO:0030146!diuresis!0.00157272375569797!1906$GO:0030802!regulation of cyclic nucleotide biosynthetic process!0.00157272375569797!1906$GO:0030808!regulation of nucleotide biosynthetic process!0.00157272375569797!1906$GO:0051482!elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)!0.00157272375569797!1906$GO:0045980!negative regulation of nucleotide metabolic process!0.00157272375569797!1906$GO:0030814!regulation of cAMP metabolic process!0.00157272375569797!1906$GO:0030799!regulation of cyclic nucleotide metabolic process!0.00167529269628697!1906$GO:0030104!water homeostasis!0.00167529269628697!1906$GO:0018987!osmoregulation!0.00183484438164763!1906$GO:0003014!renal system process!0.00183484438164763!1906$GO:0019229!regulation of vasoconstriction!0.00183484438164763!1906$GO:0051899!membrane depolarization!0.00183484438164763!1906$GO:0006140!regulation of nucleotide metabolic process!0.00196590469462246!1906$GO:0001569!patterning of blood vessels!0.00201832881981239!1906$GO:0046888!negative regulation of hormone secretion!0.00201832881981239!1906$GO:0009405!pathogenesis!0.0023083526091696!1906$GO:0014032!neural crest cell development!0.00233525648573335!1906$GO:0014033!neural crest cell differentiation!0.00233525648573335!1906$GO:0042310!vasoconstriction!0.00251635800911675!1906$GO:0050804!regulation of synaptic transmission!0.00251635800911675!1906$GO:0051048!negative regulation of secretion!0.00259936287400081!1906$GO:0051969!regulation of transmission of nerve impulse!0.00260741043707821!1906$GO:0007589!fluid secretion!0.00260741043707821!1906$GO:0046883!regulation of hormone secretion!0.00261465324384787!1906$GO:0006171!cAMP biosynthetic process!0.00261465324384787!1906$GO:0046058!cAMP metabolic process!0.00295365193143277!1906$GO:0048762!mesenchymal cell differentiation!0.00307229756927045!1906$GO:0014031!mesenchymal cell development!0.00307229756927045!1906$GO:0031644!regulation of neurological process!0.00312757565053574!1906$GO:0009880!embryonic pattern specification!0.00314544751139594!1906$GO:0048754!branching morphogenesis of a tube!0.00314544751139594!1906$GO:0009953!dorsal/ventral pattern formation!0.00314544751139594!1906$GO:0007585!respiratory gaseous exchange!0.00314544751139594!1906$GO:0015758!glucose transport!0.00314544751139594!1906$GO:0042471!ear morphogenesis!0.00314544751139594!1906$GO:0042391!regulation of membrane potential!0.00314544751139594!1906$GO:0001763!morphogenesis of a branching structure!0.00314544751139594!1906$GO:0008645!hexose transport!0.00314544751139594!1906$GO:0044403!symbiosis, encompassing mutualism through parasitism!0.00314544751139594!1906$GO:0044419!interspecies interaction between organisms!0.00314544751139594!1906$GO:0015749!monosaccharide transport!0.00314544751139594!1906$GO:0006885!regulation of pH!0.00318683497865115!1906$GO:0046879!hormone secretion!0.00322679529186308!1906$GO:0051216!cartilage development!0.00335869819013465!1906$GO:0007205!protein kinase C activation!0.0034862043251305!1906$GO:0009190!cyclic nucleotide biosynthetic process!0.00355677526288618!1906$GO:0007588!excretion!0.00355677526288618!1906$GO:0035150!regulation of tube size!0.00355677526288618!1906$GO:0050880!regulation of blood vessel size!0.00355677526288618!1906$GO:0043583!ear development!0.00355677526288618!1906$GO:0003018!vascular process in circulatory system!0.00358628674594764!1906$GO:0001666!response to hypoxia!0.00394354613369043!1906$GO:0009187!cyclic nucleotide metabolic process!0.00398879213401659!1906$GO:0001701!in utero embryonic development!0.00398879213401659!1906$GO:0009890!negative regulation of biosynthetic process!0.00401044557702982!1906$GO:0008217!regulation of blood pressure!0.00426407497143464!1906$GO:0051046!regulation of secretion!0.00451065910488376!1906$GO:0051480!cytosolic calcium ion homeostasis!0.00506996473876319!1906$GO:0003001!generation of a signal involved in cell-cell signaling!0.00506996473876319!1906$GO:0007204!elevation of cytosolic calcium ion concentration!0.00506996473876319!1906$GO:0032147!activation of protein kinase activity!0.00506996473876319!1906$GO:0035239!tube morphogenesis!0.00600494524902861!1906$GO:0007423!sensory organ development!0.00605498645943718!1906$GO:0003002!regionalization!0.00605498645943718!1906$GO:0007200!G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)!0.00605498645943718!1906$GO:0048598!embryonic morphogenesis!0.00622536486630446!1906$GO:0007507!heart development!0.00622536486630446!1906$GO:0009792!embryonic development ending in birth or egg hatching!0.00622536486630446!1906$GO:0043009!chordate embryonic development!0.00622536486630446!1906$GO:0001664!G-protein-coupled receptor binding!0.0067349582008713!1906$GO:0008643!carbohydrate transport!0.00710468812893792!1906$GO:0006874!cellular calcium ion homeostasis!0.00723629638155414!1906$GO:0055074!calcium ion homeostasis!0.00723629638155414!1906$GO:0035295!tube development!0.00723629638155414!1906$GO:0006875!cellular metal ion homeostasis!0.00739856605503077!1906$GO:0055065!metal ion homeostasis!0.00739856605503077!1906$GO:0007389!pattern specification process!0.00739856605503077!1906$GO:0050878!regulation of body fluid levels!0.00739856605503077!1906$GO:0048015!phosphoinositide-mediated signaling!0.00747457658629087!1906$GO:0001525!angiogenesis!0.00747457658629087!1906$GO:0045860!positive regulation of protein kinase activity!0.00808478305663487!1906$GO:0033674!positive regulation of kinase activity!0.00817167807084306!1906$GO:0051347!positive regulation of transferase activity!0.00817339770006672!1906$GO:0048514!blood vessel morphogenesis!0.00817339770006672!1906$GO:0048646!anatomical structure formation!0.00842193571176262!1906$GO:0008015!blood circulation!0.00863456179598885!1906$GO:0003013!circulatory system process!0.00863456179598885!1906$GO:0001568!blood vessel development!0.00876449937641393!1906$GO:0001944!vasculature development!0.00878608175058193!1906$GO:0030005!cellular di-, tri-valent inorganic cation homeostasis!0.00943634253418782!1906$GO:0055066!di-, tri-valent inorganic cation homeostasis!0.00950310910872217!1906$GO:0030003!cellular cation homeostasis!0.0102888469998933!1906$GO:0055080!cation homeostasis!0.010346483596513!1906$GO:0001501!skeletal development!0.0105545635531474!1906$GO:0005179!hormone activity!0.0107611143464199!1906$GO:0009889!regulation of biosynthetic process!0.0107611143464199!1906$GO:0008284!positive regulation of cell proliferation!0.0111502081653971!1906$GO:0005625!soluble fraction!0.0111502081653971!1906$GO:0009790!embryonic development!0.0111502081653971!1906$GO:0045859!regulation of protein kinase activity!0.0111502081653971!1906$GO:0055082!cellular chemical homeostasis!0.0111502081653971!1906$GO:0006873!cellular ion homeostasis!0.0111502081653971!1906$GO:0043549!regulation of kinase activity!0.0112889578057303!1906$GO:0051338!regulation of transferase activity!0.0114253755193352!1906$GO:0009165!nucleotide biosynthetic process!0.0116459544223585!1906$GO:0043085!positive regulation of catalytic activity!0.0116459544223585!1906$GO:0050801!ion homeostasis!0.0119936169336967!1906$GO:0019932!second-messenger-mediated signaling!0.0119936169336967!1906$GO:0051239!regulation of multicellular organismal process!0.0122964167834611!1906$GO:0007268!synaptic transmission!0.0127705168962675!1906$GO:0048878!chemical homeostasis!0.0131934048394663!1906$GO:0009888!tissue development!0.0132195481039967!1906$GO:0045934!negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process!0.0137183286971624!1906$GO:0019226!transmission of nerve impulse!0.0140813638591562!1906$GO:0051704!multi-organism process!0.0141000733635845!1906$GO:0009117!nucleotide metabolic process!0.0142865745746609!1906$GO:0009887!organ morphogenesis!0.0150957651399192!1906$GO:0055086!nucleobase, nucleoside and nucleotide metabolic process!0.015189200482662!1906$GO:0019725!cellular homeostasis!0.0153311441666558!1906$GO:0007243!protein kinase cascade!0.0153311441666558!1906$GO:0031324!negative regulation of cellular metabolic process!0.0154207877075238!1906$GO:0046903!secretion!0.0154287644354604!1906$GO:0009892!negative regulation of metabolic process!0.0173911337043123!1906$GO:0042127!regulation of cell proliferation!0.0185728492444476!1906$GO:0042592!homeostatic process!0.0188726850683756!1906$GO:0005615!extracellular space!0.0206127198619138!1906$GO:0050790!regulation of catalytic activity!0.0234524123428905!1906$GO:0007267!cell-cell signaling!0.0246356728165276!1906$GO:0065009!regulation of a molecular function!0.0256495954184492!1906$GO:0008283!cell proliferation!0.0282819116757411!1906$GO:0000267!cell fraction!0.034007458196839!1906$GO:0044421!extracellular region part!0.034075681373456!1906$GO:0065008!regulation of biological quality!0.0352437893978223!1906$GO:0048522!positive regulation of cellular process!0.0352437893978223!1906$GO:0005102!receptor binding!0.0380546724753719!1906$GO:0009653!anatomical structure morphogenesis!0.0381671933957299!1906$GO:0048518!positive regulation of biological process!0.0384593039469036!1906$GO:0048523!negative regulation of cellular process!0.040783586482986!1906$GO:0048513!organ development!0.040783586482986!1906$GO:0048519!negative regulation of biological process!0.0419765043698226!1906$GO:0006950!response to stress!0.0431188429687193!1906$GO:0048468!cell development!0.0435454150701852!1906$GO:0050877!neurological system process!0.0442104592464084!1906 | ||
|id=C515 | |id=C515 | ||
|ontology_enrichment_celltype=CL:0000066!1.58e-27!254;CL:0002076!4.01e-14!43;CL:0000220!6.54e-12!246;CL:0002321!1.89e-11!248;CL:0000076!5.45e-09!62;CL:0002368!1.12e-08!13;CL:0000223!2.59e-08!59 | |||
|ontology_enrichment_disease=DOID:120!3.70e-07!27 | |||
|ontology_enrichment_uberon=UBERON:0003104!2.88e-09!238;UBERON:0009142!2.88e-09!238;UBERON:0004119!3.04e-09!169;UBERON:0000925!3.04e-09!169;UBERON:0006595!3.04e-09!169;UBERON:0001008!4.03e-09!45;UBERON:0006554!5.00e-09!44;UBERON:0003103!9.06e-09!69;UBERON:0000481!1.07e-08!347;UBERON:0003100!4.48e-08!41;UBERON:0000475!8.82e-08!365;UBERON:0000468!1.47e-07!659;UBERON:0000065!2.76e-07!53;UBERON:0000467!2.94e-07!625;UBERON:0003064!3.07e-07!37;UBERON:0000480!4.07e-07!626;UBERON:0001004!4.59e-07!72;UBERON:0005631!7.39e-07!14;UBERON:0000158!7.39e-07!14 | |||
}} | }} |
Revision as of 14:54, 21 May 2012
Full id: C515_Small_Urothelial_Sebocyte_Prostate_Bronchial_Mallassezderived_Esophageal
Phase1 CAGE Peaks
Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data
No results for this coexpression
Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data
GO ID | GO name | FDR corrected p-value |
---|---|---|
GO:0031705 | bombesin receptor binding | 0.000917422190823815 |
GO:0031583 | G-protein signaling, phospholipase D activating pathway | 0.000917422190823815 |
GO:0043179 | rhythmic excitation | 0.000917422190823815 |
GO:0031708 | endothelin B receptor binding | 0.000917422190823815 |
GO:0031707 | endothelin A receptor binding | 0.000917422190823815 |
GO:0060024 | rhythmic synaptic transmission | 0.000917422190823815 |
GO:0030815 | negative regulation of cAMP metabolic process | 0.00137613328623572 |
GO:0030818 | negative regulation of cAMP biosynthetic process | 0.00137613328623572 |
GO:0030809 | negative regulation of nucleotide biosynthetic process | 0.00137613328623572 |
GO:0030803 | negative regulation of cyclic nucleotide biosynthetic process | 0.00137613328623572 |
GO:0042474 | middle ear morphogenesis | 0.00137613328623572 |
GO:0030800 | negative regulation of cyclic nucleotide metabolic process | 0.00137613328623572 |
GO:0030147 | natriuresis | 0.00157272375569797 |
GO:0030817 | regulation of cAMP biosynthetic process | 0.00157272375569797 |
GO:0003091 | renal water homeostasis | 0.00157272375569797 |
GO:0030146 | diuresis | 0.00157272375569797 |
GO:0030802 | regulation of cyclic nucleotide biosynthetic process | 0.00157272375569797 |
GO:0030808 | regulation of nucleotide biosynthetic process | 0.00157272375569797 |
GO:0051482 | elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) | 0.00157272375569797 |
GO:0045980 | negative regulation of nucleotide metabolic process | 0.00157272375569797 |
GO:0030814 | regulation of cAMP metabolic process | 0.00157272375569797 |
GO:0030799 | regulation of cyclic nucleotide metabolic process | 0.00167529269628697 |
GO:0030104 | water homeostasis | 0.00167529269628697 |
GO:0018987 | osmoregulation | 0.00183484438164763 |
GO:0003014 | renal system process | 0.00183484438164763 |
GO:0019229 | regulation of vasoconstriction | 0.00183484438164763 |
GO:0051899 | membrane depolarization | 0.00183484438164763 |
GO:0006140 | regulation of nucleotide metabolic process | 0.00196590469462246 |
GO:0001569 | patterning of blood vessels | 0.00201832881981239 |
GO:0046888 | negative regulation of hormone secretion | 0.00201832881981239 |
GO:0009405 | pathogenesis | 0.0023083526091696 |
GO:0014032 | neural crest cell development | 0.00233525648573335 |
GO:0014033 | neural crest cell differentiation | 0.00233525648573335 |
GO:0042310 | vasoconstriction | 0.00251635800911675 |
GO:0050804 | regulation of synaptic transmission | 0.00251635800911675 |
GO:0051048 | negative regulation of secretion | 0.00259936287400081 |
GO:0051969 | regulation of transmission of nerve impulse | 0.00260741043707821 |
GO:0007589 | fluid secretion | 0.00260741043707821 |
GO:0046883 | regulation of hormone secretion | 0.00261465324384787 |
GO:0006171 | cAMP biosynthetic process | 0.00261465324384787 |
GO:0046058 | cAMP metabolic process | 0.00295365193143277 |
GO:0048762 | mesenchymal cell differentiation | 0.00307229756927045 |
GO:0014031 | mesenchymal cell development | 0.00307229756927045 |
GO:0031644 | regulation of neurological process | 0.00312757565053574 |
GO:0009880 | embryonic pattern specification | 0.00314544751139594 |
GO:0048754 | branching morphogenesis of a tube | 0.00314544751139594 |
GO:0009953 | dorsal/ventral pattern formation | 0.00314544751139594 |
GO:0007585 | respiratory gaseous exchange | 0.00314544751139594 |
GO:0015758 | glucose transport | 0.00314544751139594 |
GO:0042471 | ear morphogenesis | 0.00314544751139594 |
GO:0042391 | regulation of membrane potential | 0.00314544751139594 |
GO:0001763 | morphogenesis of a branching structure | 0.00314544751139594 |
GO:0008645 | hexose transport | 0.00314544751139594 |
GO:0044403 | symbiosis, encompassing mutualism through parasitism | 0.00314544751139594 |
GO:0044419 | interspecies interaction between organisms | 0.00314544751139594 |
GO:0015749 | monosaccharide transport | 0.00314544751139594 |
GO:0006885 | regulation of pH | 0.00318683497865115 |
GO:0046879 | hormone secretion | 0.00322679529186308 |
GO:0051216 | cartilage development | 0.00335869819013465 |
GO:0007205 | protein kinase C activation | 0.0034862043251305 |
GO:0009190 | cyclic nucleotide biosynthetic process | 0.00355677526288618 |
GO:0007588 | excretion | 0.00355677526288618 |
GO:0035150 | regulation of tube size | 0.00355677526288618 |
GO:0050880 | regulation of blood vessel size | 0.00355677526288618 |
GO:0043583 | ear development | 0.00355677526288618 |
GO:0003018 | vascular process in circulatory system | 0.00358628674594764 |
GO:0001666 | response to hypoxia | 0.00394354613369043 |
GO:0009187 | cyclic nucleotide metabolic process | 0.00398879213401659 |
GO:0001701 | in utero embryonic development | 0.00398879213401659 |
GO:0009890 | negative regulation of biosynthetic process | 0.00401044557702982 |
GO:0008217 | regulation of blood pressure | 0.00426407497143464 |
GO:0051046 | regulation of secretion | 0.00451065910488376 |
GO:0051480 | cytosolic calcium ion homeostasis | 0.00506996473876319 |
GO:0003001 | generation of a signal involved in cell-cell signaling | 0.00506996473876319 |
GO:0007204 | elevation of cytosolic calcium ion concentration | 0.00506996473876319 |
GO:0032147 | activation of protein kinase activity | 0.00506996473876319 |
GO:0035239 | tube morphogenesis | 0.00600494524902861 |
GO:0007423 | sensory organ development | 0.00605498645943718 |
GO:0003002 | regionalization | 0.00605498645943718 |
GO:0007200 | G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) | 0.00605498645943718 |
GO:0048598 | embryonic morphogenesis | 0.00622536486630446 |
GO:0007507 | heart development | 0.00622536486630446 |
GO:0009792 | embryonic development ending in birth or egg hatching | 0.00622536486630446 |
GO:0043009 | chordate embryonic development | 0.00622536486630446 |
GO:0001664 | G-protein-coupled receptor binding | 0.0067349582008713 |
GO:0008643 | carbohydrate transport | 0.00710468812893792 |
GO:0006874 | cellular calcium ion homeostasis | 0.00723629638155414 |
GO:0055074 | calcium ion homeostasis | 0.00723629638155414 |
GO:0035295 | tube development | 0.00723629638155414 |
GO:0006875 | cellular metal ion homeostasis | 0.00739856605503077 |
GO:0055065 | metal ion homeostasis | 0.00739856605503077 |
GO:0007389 | pattern specification process | 0.00739856605503077 |
GO:0050878 | regulation of body fluid levels | 0.00739856605503077 |
GO:0048015 | phosphoinositide-mediated signaling | 0.00747457658629087 |
GO:0001525 | angiogenesis | 0.00747457658629087 |
GO:0045860 | positive regulation of protein kinase activity | 0.00808478305663487 |
GO:0033674 | positive regulation of kinase activity | 0.00817167807084306 |
GO:0051347 | positive regulation of transferase activity | 0.00817339770006672 |
GO:0048514 | blood vessel morphogenesis | 0.00817339770006672 |
GO:0048646 | anatomical structure formation | 0.00842193571176262 |
GO:0008015 | blood circulation | 0.00863456179598885 |
GO:0003013 | circulatory system process | 0.00863456179598885 |
GO:0001568 | blood vessel development | 0.00876449937641393 |
GO:0001944 | vasculature development | 0.00878608175058193 |
GO:0030005 | cellular di-, tri-valent inorganic cation homeostasis | 0.00943634253418782 |
GO:0055066 | di-, tri-valent inorganic cation homeostasis | 0.00950310910872217 |
GO:0030003 | cellular cation homeostasis | 0.0102888469998933 |
GO:0055080 | cation homeostasis | 0.010346483596513 |
GO:0001501 | skeletal development | 0.0105545635531474 |
GO:0005179 | hormone activity | 0.0107611143464199 |
GO:0009889 | regulation of biosynthetic process | 0.0107611143464199 |
GO:0008284 | positive regulation of cell proliferation | 0.0111502081653971 |
GO:0005625 | soluble fraction | 0.0111502081653971 |
GO:0009790 | embryonic development | 0.0111502081653971 |
GO:0045859 | regulation of protein kinase activity | 0.0111502081653971 |
GO:0055082 | cellular chemical homeostasis | 0.0111502081653971 |
GO:0006873 | cellular ion homeostasis | 0.0111502081653971 |
GO:0043549 | regulation of kinase activity | 0.0112889578057303 |
GO:0051338 | regulation of transferase activity | 0.0114253755193352 |
GO:0009165 | nucleotide biosynthetic process | 0.0116459544223585 |
GO:0043085 | positive regulation of catalytic activity | 0.0116459544223585 |
GO:0050801 | ion homeostasis | 0.0119936169336967 |
GO:0019932 | second-messenger-mediated signaling | 0.0119936169336967 |
GO:0051239 | regulation of multicellular organismal process | 0.0122964167834611 |
GO:0007268 | synaptic transmission | 0.0127705168962675 |
GO:0048878 | chemical homeostasis | 0.0131934048394663 |
GO:0009888 | tissue development | 0.0132195481039967 |
GO:0045934 | negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process | 0.0137183286971624 |
GO:0019226 | transmission of nerve impulse | 0.0140813638591562 |
GO:0051704 | multi-organism process | 0.0141000733635845 |
GO:0009117 | nucleotide metabolic process | 0.0142865745746609 |
GO:0009887 | organ morphogenesis | 0.0150957651399192 |
GO:0055086 | nucleobase, nucleoside and nucleotide metabolic process | 0.015189200482662 |
GO:0019725 | cellular homeostasis | 0.0153311441666558 |
GO:0007243 | protein kinase cascade | 0.0153311441666558 |
GO:0031324 | negative regulation of cellular metabolic process | 0.0154207877075238 |
GO:0046903 | secretion | 0.0154287644354604 |
GO:0009892 | negative regulation of metabolic process | 0.0173911337043123 |
GO:0042127 | regulation of cell proliferation | 0.0185728492444476 |
GO:0042592 | homeostatic process | 0.0188726850683756 |
GO:0005615 | extracellular space | 0.0206127198619138 |
GO:0050790 | regulation of catalytic activity | 0.0234524123428905 |
GO:0007267 | cell-cell signaling | 0.0246356728165276 |
GO:0065009 | regulation of a molecular function | 0.0256495954184492 |
GO:0008283 | cell proliferation | 0.0282819116757411 |
GO:0000267 | cell fraction | 0.034007458196839 |
GO:0044421 | extracellular region part | 0.034075681373456 |
GO:0065008 | regulation of biological quality | 0.0352437893978223 |
GO:0048522 | positive regulation of cellular process | 0.0352437893978223 |
GO:0005102 | receptor binding | 0.0380546724753719 |
GO:0009653 | anatomical structure morphogenesis | 0.0381671933957299 |
GO:0048518 | positive regulation of biological process | 0.0384593039469036 |
GO:0048523 | negative regulation of cellular process | 0.040783586482986 |
GO:0048513 | organ development | 0.040783586482986 |
GO:0048519 | negative regulation of biological process | 0.0419765043698226 |
GO:0006950 | response to stress | 0.0431188429687193 |
GO:0048468 | cell development | 0.0435454150701852 |
GO:0050877 | neurological system process | 0.0442104592464084 |
Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>
Ontology term | p-value | n |
---|---|---|
epithelial cell | 1.58e-27 | 254 |
endo-epithelial cell | 4.01e-14 | 43 |
embryonic cell | 1.89e-11 | 248 |
squamous epithelial cell | 5.45e-09 | 62 |
respiratory epithelial cell | 1.12e-08 | 13 |
endodermal cell | 2.59e-08 | 59 |
Ontology term | p-value | n |
---|---|---|
mesenchyme | 2.88e-09 | 238 |
entire embryonic mesenchyme | 2.88e-09 | 238 |
endoderm-derived structure | 3.04e-09 | 169 |
endoderm | 3.04e-09 | 169 |
presumptive endoderm | 3.04e-09 | 169 |
renal system | 4.03e-09 | 45 |
urinary system structure | 5.00e-09 | 44 |
compound organ | 9.06e-09 | 69 |
multi-tissue structure | 1.07e-08 | 347 |
female organism | 4.48e-08 | 41 |
organism subdivision | 8.82e-08 | 365 |
multi-cellular organism | 1.47e-07 | 659 |
respiratory tract | 2.76e-07 | 53 |
anatomical system | 2.94e-07 | 625 |
intermediate mesoderm | 3.07e-07 | 37 |
anatomical group | 4.07e-07 | 626 |
respiratory system | 4.59e-07 | 72 |
extraembryonic membrane | 7.39e-07 | 14 |
membranous layer | 7.39e-07 | 14 |
Ontology term | p-value | n |
---|---|---|
female reproductive organ cancer | 3.70e-07 | 27 |
Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data
Novel motifs
JASPAR motifs
Motifs | -log10(p-value) |
---|---|
{{{tfbs_overrepresentation_jaspar}}} |
ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data
No analysis results for this cluster
Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data
This analysis result is provided for C0 - C305 clusters.