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|full_id=C2533_CD14_Neutrophils_Whole_Eosinophils_blood_Peripheral_CD14CD16
|full_id=C2533_CD14_Neutrophils_Whole_Eosinophils_blood_Peripheral_CD14CD16
|id=C2533
|id=C2533
|ontology_enrichment_celltype=CL:0000766!8.49e-65!76;CL:0002009!2.41e-60!65;CL:0002194!2.06e-58!63;CL:0000576!2.06e-58!63;CL:0000040!2.06e-58!63;CL:0000559!2.06e-58!63;CL:0000763!2.74e-57!112;CL:0000049!2.74e-57!112;CL:0000738!3.35e-55!140;CL:0000557!3.63e-55!71;CL:0000037!3.71e-53!172;CL:0000566!3.71e-53!172;CL:0002057!2.66e-52!42;CL:0000839!3.45e-52!70;CL:0002032!2.07e-49!165;CL:0000837!2.07e-49!165;CL:0000988!2.00e-48!182;CL:0000860!1.09e-47!45;CL:0002087!1.68e-45!119;CL:0002031!6.65e-42!124;CL:0002393!1.99e-12!9;CL:0002397!1.99e-12!9;CL:0000134!8.47e-12!358;CL:0000094!1.47e-11!8;CL:0002320!4.71e-11!365;CL:0000219!1.67e-08!390;CL:0000081!8.31e-08!11;CL:0000990!2.25e-07!8;CL:0000451!3.36e-07!10;CL:0000840!5.19e-07!5;CL:0001029!5.19e-07!5
|ontology_enrichment_disease=
|ontology_enrichment_uberon=UBERON:0002390!7.81e-62!102;UBERON:0003061!7.81e-62!102;UBERON:0002193!4.13e-57!112;UBERON:0002371!2.77e-48!80;UBERON:0001474!2.13e-43!86;UBERON:0002405!1.23e-36!115;UBERON:0004765!8.98e-34!101;UBERON:0001434!8.98e-34!101;UBERON:0003081!1.59e-20!216;UBERON:0002204!1.38e-14!167;UBERON:0000178!9.73e-13!15;UBERON:0000179!9.73e-13!15;UBERON:0000463!9.73e-13!15;UBERON:0007023!1.23e-11!115;UBERON:0002384!1.65e-10!375
}}
}}

Revision as of 14:25, 21 May 2012


Full id: C2533_CD14_Neutrophils_Whole_Eosinophils_blood_Peripheral_CD14CD16



Phase1 CAGE Peaks

Hg19::chr1:158801209..158801216,+p2@MNDA
Hg19::chr1:158801218..158801220,+p9@MNDA
Hg19::chr1:158801238..158801255,+p4@MNDA
Hg19::chr8:48319394..48319421,+p@chr8:48319394..48319421
+


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Cell Type
Ontology termp-valuen
myeloid leukocyte8.49e-6576
macrophage dendritic cell progenitor2.41e-6065
monopoietic cell2.06e-5863
monocyte2.06e-5863
monoblast2.06e-5863
promonocyte2.06e-5863
myeloid cell2.74e-57112
common myeloid progenitor2.74e-57112
leukocyte3.35e-55140
granulocyte monocyte progenitor cell3.63e-5571
hematopoietic stem cell3.71e-53172
angioblastic mesenchymal cell3.71e-53172
CD14-positive, CD16-negative classical monocyte2.66e-5242
myeloid lineage restricted progenitor cell3.45e-5270
hematopoietic oligopotent progenitor cell2.07e-49165
hematopoietic multipotent progenitor cell2.07e-49165
hematopoietic cell2.00e-48182
classical monocyte1.09e-4745
nongranular leukocyte1.68e-45119
hematopoietic lineage restricted progenitor cell6.65e-42124
intermediate monocyte1.99e-129
CD14-positive, CD16-positive monocyte1.99e-129
mesenchymal cell8.47e-12358
granulocyte1.47e-118
connective tissue cell4.71e-11365
motile cell1.67e-08390
blood cell8.31e-0811
conventional dendritic cell2.25e-078
dendritic cell3.36e-0710
immature conventional dendritic cell5.19e-075
common dendritic progenitor5.19e-075
Uber Anatomy
Ontology termp-valuen
hematopoietic system7.81e-62102
blood island7.81e-62102
hemolymphoid system4.13e-57112
bone marrow2.77e-4880
bone element2.13e-4386
immune system1.23e-36115
skeletal element8.98e-34101
skeletal system8.98e-34101
lateral plate mesoderm1.59e-20216
musculoskeletal system1.38e-14167
blood9.73e-1315
haemolymphatic fluid9.73e-1315
organism substance9.73e-1315
adult organism1.23e-11115
connective tissue1.65e-10375


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.