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|full_id=C2165_mesothelioma_adenocarcinoma_epidermoid_breast_colon_argyrophil_Prostate
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|id=C2165
|id=C2165
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|ontology_enrichment_disease=
|ontology_enrichment_uberon=UBERON:0001049!8.68e-22!57;UBERON:0005068!8.68e-22!57;UBERON:0006241!8.68e-22!57;UBERON:0007135!8.68e-22!57;UBERON:0002780!6.17e-18!41;UBERON:0001890!6.17e-18!41;UBERON:0006240!6.17e-18!41;UBERON:0001869!1.65e-17!32;UBERON:0002020!1.94e-17!34;UBERON:0003528!1.94e-17!34;UBERON:0003080!3.05e-17!42;UBERON:0001893!3.11e-17!34;UBERON:0002616!6.19e-17!59;UBERON:0002791!2.12e-16!33;UBERON:0003075!1.25e-15!86;UBERON:0007284!1.25e-15!86;UBERON:0001950!1.70e-15!20;UBERON:0005743!1.77e-15!86;UBERON:0001017!2.70e-15!82;UBERON:0002619!5.28e-15!22;UBERON:0002346!6.30e-15!90;UBERON:0000955!3.56e-14!69;UBERON:0006238!3.56e-14!69;UBERON:0000956!1.53e-13!25;UBERON:0000203!1.53e-13!25;UBERON:0000073!1.56e-12!94;UBERON:0001016!1.56e-12!94;UBERON:0007023!4.33e-12!115;UBERON:0003056!9.43e-11!61;UBERON:0000025!1.03e-08!194;UBERON:0000473!5.36e-07!8
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Revision as of 14:20, 21 May 2012


Full id: C2165_mesothelioma_adenocarcinoma_epidermoid_breast_colon_argyrophil_Prostate



Phase1 CAGE Peaks

Hg19::chr11:75140914..75140942,-p2@KLHL35
Hg19::chr11:75140966..75140979,-p7@KLHL35
Hg19::chr11:75140985..75141007,-p4@KLHL35
Hg19::chr11:75141017..75141039,-p3@KLHL35


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
neural tube8.68e-2257
neural rod8.68e-2257
future spinal cord8.68e-2257
neural keel8.68e-2257
regional part of forebrain6.17e-1841
forebrain6.17e-1841
future forebrain6.17e-1841
cerebral hemisphere1.65e-1732
gray matter1.94e-1734
brain grey matter1.94e-1734
anterior neural tube3.05e-1742
telencephalon3.11e-1734
regional part of brain6.19e-1759
regional part of telencephalon2.12e-1633
neural plate1.25e-1586
presumptive neural plate1.25e-1586
neocortex1.70e-1520
central nervous system2.70e-1582
regional part of cerebral cortex5.28e-1522
neurectoderm6.30e-1590
brain3.56e-1469
future brain3.56e-1469
cerebral cortex1.53e-1325
pallium1.53e-1325
regional part of nervous system1.56e-1294
nervous system1.56e-1294
adult organism4.33e-12115
pre-chordal neural plate9.43e-1161
tube1.03e-08194
testis5.36e-078


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.