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|full_id=C1621_Basophils_CD14CD16_CD14_CD4_CD34_Natural_Peripheral
|full_id=C1621_Basophils_CD14CD16_CD14_CD4_CD34_Natural_Peripheral
|id=C1621
|id=C1621
|ontology_enrichment_celltype=CL:0000738!8.39e-56!140;CL:0000037!4.32e-48!172;CL:0000566!4.32e-48!172;CL:0002031!5.99e-44!124;CL:0002032!1.11e-43!165;CL:0000837!1.11e-43!165;CL:0000988!3.24e-43!182;CL:0002087!8.55e-42!119;CL:0002057!8.94e-39!42;CL:0000860!5.56e-35!45;CL:0000766!1.27e-34!76;CL:0000557!6.50e-30!71;CL:0000763!4.02e-27!112;CL:0000049!4.02e-27!112;CL:0000839!2.62e-26!70;CL:0002009!1.03e-25!65;CL:0002194!3.55e-24!63;CL:0000576!3.55e-24!63;CL:0000040!3.55e-24!63;CL:0000559!3.55e-24!63;CL:0000134!2.27e-18!358;CL:0002320!1.16e-17!365;CL:0000838!3.15e-15!52;CL:0000542!1.04e-14!53;CL:0000051!1.04e-14!53;CL:0000791!1.15e-14!18;CL:0000789!1.15e-14!18;CL:0002420!1.15e-14!18;CL:0002419!1.15e-14!18;CL:0000790!1.15e-14!18;CL:0000219!1.35e-14!390;CL:0000034!3.14e-11!444;CL:0002393!3.99e-11!9;CL:0002397!3.99e-11!9;CL:0000048!4.91e-11!430;CL:0000084!8.96e-11!25;CL:0000827!8.96e-11!25;CL:0000723!1.11e-10!436;CL:0000625!4.76e-10!11;CL:0000094!6.36e-09!8;CL:0000624!1.61e-07!6
|ontology_enrichment_disease=
|ontology_enrichment_uberon=UBERON:0002390!1.32e-31!102;UBERON:0003061!1.32e-31!102;UBERON:0002371!6.94e-28!80;UBERON:0002193!2.07e-27!112;UBERON:0001474!1.80e-24!86;UBERON:0004765!7.52e-18!101;UBERON:0001434!7.52e-18!101;UBERON:0002405!6.89e-17!115;UBERON:0002384!1.41e-16!375;UBERON:0003081!2.62e-08!216
}}
}}

Revision as of 14:13, 21 May 2012


Full id: C1621_Basophils_CD14CD16_CD14_CD4_CD34_Natural_Peripheral



Phase1 CAGE Peaks

Hg19::chr11:128141629..128141667,+p@chr11:128141629..128141667
+
Hg19::chr13:49227664..49227675,-p@chr13:49227664..49227675
-
Hg19::chr13:49227677..49227696,-p@chr13:49227677..49227696
-
Hg19::chr2:238583830..238583841,+p@chr2:238583830..238583841
+
Hg19::chr2:238596652..238596664,+p@chr2:238596652..238596664
+


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Cell Type
Ontology termp-valuen
leukocyte8.39e-56140
hematopoietic stem cell4.32e-48172
angioblastic mesenchymal cell4.32e-48172
hematopoietic lineage restricted progenitor cell5.99e-44124
hematopoietic oligopotent progenitor cell1.11e-43165
hematopoietic multipotent progenitor cell1.11e-43165
hematopoietic cell3.24e-43182
nongranular leukocyte8.55e-42119
CD14-positive, CD16-negative classical monocyte8.94e-3942
classical monocyte5.56e-3545
myeloid leukocyte1.27e-3476
granulocyte monocyte progenitor cell6.50e-3071
myeloid cell4.02e-27112
common myeloid progenitor4.02e-27112
myeloid lineage restricted progenitor cell2.62e-2670
macrophage dendritic cell progenitor1.03e-2565
monopoietic cell3.55e-2463
monocyte3.55e-2463
monoblast3.55e-2463
promonocyte3.55e-2463
mesenchymal cell2.27e-18358
connective tissue cell1.16e-17365
lymphoid lineage restricted progenitor cell3.15e-1552
lymphocyte1.04e-1453
common lymphoid progenitor1.04e-1453
mature alpha-beta T cell1.15e-1418
alpha-beta T cell1.15e-1418
immature T cell1.15e-1418
mature T cell1.15e-1418
immature alpha-beta T cell1.15e-1418
motile cell1.35e-14390
stem cell3.14e-11444
intermediate monocyte3.99e-119
CD14-positive, CD16-positive monocyte3.99e-119
multi fate stem cell4.91e-11430
T cell8.96e-1125
pro-T cell8.96e-1125
somatic stem cell1.11e-10436
CD8-positive, alpha-beta T cell4.76e-1011
granulocyte6.36e-098
CD4-positive, alpha-beta T cell1.61e-076
Uber Anatomy
Ontology termp-valuen
hematopoietic system1.32e-31102
blood island1.32e-31102
bone marrow6.94e-2880
hemolymphoid system2.07e-27112
bone element1.80e-2486
skeletal element7.52e-18101
skeletal system7.52e-18101
immune system6.89e-17115
connective tissue1.41e-16375
lateral plate mesoderm2.62e-08216


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.